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Thiamine hydrochloride - 99%, high purity , CAS No.67-03-8

12 Citations

≥99%

CAS#: 67-03-8
Molecular Weight: 337.27
Beilstein Registry Number: 3851771
EC Number: 200-641-8
MDL number: MFCD00012780
PubChem CID: 6202

Item Number

T283819

Grouped product items
SKU	Size	Availability	Price
T283819-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$27.90
T283819-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$68.90
T283819-250g	250g	3	$127.90
T283819-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$240.90

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Anti-infection (0) HBV (0) Vitamin-B complex (0)

Basic Description

Synonyms	Lixa-beta \| Thiamine chloride, hydrochloride \| Thiamine for system suitability \| THIAMINE HYDROCHLORIDE (EP MONOGRAPH) \| Thiamine, chloride, hydrochloride \| thymine hydrochloride \| UNII-M572600E5P \| NCGC00017013-01 \| Bevitine \| Thiamin dichloride \| Thiami
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Thiamine Hydrochloride is a cofactor required for oxidation of carbohydrates and for the synthesis of ribose.Thiamine is an essential coenzyme in carbohydrate metabolism. Deficiency of thiamine causes beriberi, a neurological and cardiovascular disease. T
Storage Temp	Store at 2-8°C,Protected from light,Argon charged
Shipped In	Wet ice
Product Description	Thiamine or vitamin B1 is a water-soluble vitamin of the B complex, its phosphate derivatives are involved in many cellular processes.Thiamine is a water-soluble vitamin-B complex. Structurally, it possesses a five-membered thiazolium ring and a six-membered amino-pyrimidine ring connected by a methyl group. Thiamine is naturally available in fruits, vegetables, poultry, eggs. A cofactor required for oxidation of carbohydrates and for the synthesis of ribose. application： Thiamine hydrochloride has been used as a vitamin supplement to the holidic medium and in bacterial growth medium.

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol;chloride;hydrochloride
INCHI	InChI=1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
InChi Key	DPJRMOMPQZCRJU-UHFFFAOYSA-M
Canonical SMILES	CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
Isomeric SMILES	CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-]
WGK Germany	1
RTECS	XI7350000
Alternate CAS	59-43-8
PubChem CID	6202
Molecular Weight	337.27
Beilstein	3851771
Reaxy-Rn	3851771

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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11 results found

Lot Number	Certificate Type	Date	Item
C2517524	Certificate of Analysis	Mar 21, 2025	T283819
C2517525	Certificate of Analysis	Mar 21, 2025	T283819
C2517528	Certificate of Analysis	Mar 21, 2025	T283819
K2413420	Certificate of Analysis	Nov 19, 2024	T283819
K2413424	Certificate of Analysis	Nov 19, 2024	T283819
J2410635	Certificate of Analysis	Oct 17, 2024	T283819
D2324128	Certificate of Analysis	Nov 18, 2021	T283819
E2308143	Certificate of Analysis	Nov 18, 2021	T283819
F2417096	Certificate of Analysis	Nov 18, 2021	T283819
J2214251	Certificate of Analysis	Nov 18, 2021	T283819
K2302079	Certificate of Analysis	Nov 18, 2021	T283819

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Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
WGK Germany	1
RTECS	XI7350000
Reaxy-Rn	3851771
Merck Index	9295

Alternative Products

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Citations of This Product

How to Cite Aladdin Scientific Products?

1. Taoyue Yuan, Shunke Ding, Fei Xue, Zhenqi Du, Xinyu Yang, Qingzhi Han, Mengtao Ma, Xiaoyan Chen. (2024) Reactivity and reaction pathways of peroxymonosulfate and peroxydisulfate with neonicotinoid insecticides. WATER RESEARCH, 248 (120852). [PMID:37976950] [10.1016/j.watres.2023.120852]
2. Yuelong Xu, Jingyue Wang, Shasha Wang, Zuozhao Zhai, Bin Ren, Zhi Tian, Lihui Zhang, Zhenfa Liu. (2023) Lattice defective and N, S co-doped carbon nanotubes for trifunctional electrocatalyst application. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 48 (34340). [PMID:] [10.1016/j.ijhydene.2023.05.189]
3. Yu Fan, Xin Wang, He Huang, Yumeng Yang, Jinlin Guo, Shajie Luo, Meilian Zhao, Yang Li. (2023) A visual ratiometric fluorescence sensor for glutathione response based on MnO2 nanowires as an oxidant, quencher and recognition unit. Analytical Methods, 15 (4): (419-429). [PMID:36606523] [10.1039/D2AY01812H]
4. Zhang Jing-Xian, Lv Chun-Lin, Tang Chang, Jiang Lu-Yao, Wang Ai-Jun, Feng Jiu-Ju. (2022) Ultrasensitive sandwich-typed electrochemical immunoassay for detection of squamous cell carcinoma antigen based on highly branched PtCo nanocrystals and dendritic mesoporous SiO2@AuPt nanoparticles. MICROCHIMICA ACTA, 189 (11): (1-11). [PMID:36219254] [10.1007/s00604-022-05520-1]
5. Yanshen Nie, Li Yu, Lianlian Mao, Wenxuan Zou, Xiufeng Zhang, Jie Zhao. (2022) Vitamin B1 THIAMIN REQUIRING1 synthase mediates the maintenance of chloroplast function by regulating sugar and fatty acid metabolism in rice. Journal of Integrative Plant Biology, 64 (8): (1575-1595). [PMID:35603832] [10.1111/jipb.13283]
6. Yi Ma, Mawda Elmhadi, Chao Wang, Hao Zhang, Hongrong Wang. (2021) Dietary supplementation of thiamine down-regulates the expression of mitophagy and endoplasmic reticulum stress-related genes in the rumen epithelium of goats during high-concentrate diet feeding. Italian Journal of Animal Science, 20 (1): (2220-2231). [PMID:] [10.1080/1828051X.2021.1985944]
7. Naymul Karim, Mohammad Rezaul Islam Shishir, Tao Bao, Wei Chen. (2021) Effect of cold plasma pretreated hot-air drying on the physicochemical characteristics, nutritional values and antioxidant activity of shiitake mushroom. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (15): (6271-6280). [PMID:33949697] [10.1002/jsfa.11296]
8. Linyu Wang, Yi Xie, Yuxi Yang, Huihui Liang, Li Wang, Yonghai Song. (2020) Electroactive Covalent Organic Frameworks/Carbon Nanotubes Composites for Electrochemical Sensing. ACS Applied Nano Materials, 3 (2): (1412–1419). [PMID:] [10.1021/acsanm.9b02257]
9. Pengjuan Ni, Dafeng Jiang, Chuanxia Chen, Yuanyuan Jiang, Yizhong Lu, Zhenlu Zhao. (2018) Highly sensitive fluorescent detection of glutathione and histidine based on the Cu(II)-thiamine system. ANALYST, 143 (18): (4442-4447). [PMID:30151530] [10.1039/C8AN01201F]
10. Xiaona Li, Dandan Han, Yan Wang, Shichao Du, Yumin Liu, Jiaqi Zhang, Bo Yu, Baohong Hou, Junbo Gong. (2016) Measurement of Solubility of Thiamine Hydrochloride Hemihydrate in Three Binary Solvents and Mixing Properties of Solutions. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 61 (10): (3665–3678). [PMID:] [10.1021/acs.jced.6b00613]
11. Ying Li, Changyin Lv, Qiang Sun, Ying Zhao, Yunjing Li. (2014) Chromatographic characteristics of water-soluble vitamins with irradiation processing and its application. Analytical Methods, 7 (1): (155-160). [PMID:] [10.1039/C4AY01312C]
12. Jinghui Zhu, Shaopu Liu, Zhongfang Liu, Yuanfang Li, Man Qiao, Xiaoli Hu. (2014) Enhanced spectrofluorimetric determination of hypochlorite based on the catalytic oxidation of thiamine to thiochrome in the presence of trace ferrocyanide. RSC Advances, 4 (12): (5990-5994). [PMID:] [10.1039/C3RA46170J]

References

1. Taoyue Yuan, Shunke Ding, Fei Xue, Zhenqi Du, Xinyu Yang, Qingzhi Han, Mengtao Ma, Xiaoyan Chen. (2024) Reactivity and reaction pathways of peroxymonosulfate and peroxydisulfate with neonicotinoid insecticides. WATER RESEARCH, 248 (120852). [PMID:37976950] [10.1016/j.watres.2023.120852]
2. Yuelong Xu, Jingyue Wang, Shasha Wang, Zuozhao Zhai, Bin Ren, Zhi Tian, Lihui Zhang, Zhenfa Liu. (2023) Lattice defective and N, S co-doped carbon nanotubes for trifunctional electrocatalyst application. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 48 (34340). [PMID:] [10.1016/j.ijhydene.2023.05.189]
3. Yu Fan, Xin Wang, He Huang, Yumeng Yang, Jinlin Guo, Shajie Luo, Meilian Zhao, Yang Li. (2023) A visual ratiometric fluorescence sensor for glutathione response based on MnO2 nanowires as an oxidant, quencher and recognition unit. Analytical Methods, 15 (4): (419-429). [PMID:36606523] [10.1039/D2AY01812H]
4. Zhang Jing-Xian, Lv Chun-Lin, Tang Chang, Jiang Lu-Yao, Wang Ai-Jun, Feng Jiu-Ju. (2022) Ultrasensitive sandwich-typed electrochemical immunoassay for detection of squamous cell carcinoma antigen based on highly branched PtCo nanocrystals and dendritic mesoporous SiO2@AuPt nanoparticles. MICROCHIMICA ACTA, 189 (11): (1-11). [PMID:36219254] [10.1007/s00604-022-05520-1]
5. Yanshen Nie, Li Yu, Lianlian Mao, Wenxuan Zou, Xiufeng Zhang, Jie Zhao. (2022) Vitamin B1 THIAMIN REQUIRING1 synthase mediates the maintenance of chloroplast function by regulating sugar and fatty acid metabolism in rice. Journal of Integrative Plant Biology, 64 (8): (1575-1595). [PMID:35603832] [10.1111/jipb.13283]
6. Yi Ma, Mawda Elmhadi, Chao Wang, Hao Zhang, Hongrong Wang. (2021) Dietary supplementation of thiamine down-regulates the expression of mitophagy and endoplasmic reticulum stress-related genes in the rumen epithelium of goats during high-concentrate diet feeding. Italian Journal of Animal Science, 20 (1): (2220-2231). [PMID:] [10.1080/1828051X.2021.1985944]
7. Naymul Karim, Mohammad Rezaul Islam Shishir, Tao Bao, Wei Chen. (2021) Effect of cold plasma pretreated hot-air drying on the physicochemical characteristics, nutritional values and antioxidant activity of shiitake mushroom. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (15): (6271-6280). [PMID:33949697] [10.1002/jsfa.11296]
8. Linyu Wang, Yi Xie, Yuxi Yang, Huihui Liang, Li Wang, Yonghai Song. (2020) Electroactive Covalent Organic Frameworks/Carbon Nanotubes Composites for Electrochemical Sensing. ACS Applied Nano Materials, 3 (2): (1412–1419). [PMID:] [10.1021/acsanm.9b02257]
9. Pengjuan Ni, Dafeng Jiang, Chuanxia Chen, Yuanyuan Jiang, Yizhong Lu, Zhenlu Zhao. (2018) Highly sensitive fluorescent detection of glutathione and histidine based on the Cu(II)-thiamine system. ANALYST, 143 (18): (4442-4447). [PMID:30151530] [10.1039/C8AN01201F]
10. Xiaona Li, Dandan Han, Yan Wang, Shichao Du, Yumin Liu, Jiaqi Zhang, Bo Yu, Baohong Hou, Junbo Gong. (2016) Measurement of Solubility of Thiamine Hydrochloride Hemihydrate in Three Binary Solvents and Mixing Properties of Solutions. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 61 (10): (3665–3678). [PMID:] [10.1021/acs.jced.6b00613]
11. Ying Li, Changyin Lv, Qiang Sun, Ying Zhao, Yunjing Li. (2014) Chromatographic characteristics of water-soluble vitamins with irradiation processing and its application. Analytical Methods, 7 (1): (155-160). [PMID:] [10.1039/C4AY01312C]
12. Jinghui Zhu, Shaopu Liu, Zhongfang Liu, Yuanfang Li, Man Qiao, Xiaoli Hu. (2014) Enhanced spectrofluorimetric determination of hypochlorite based on the catalytic oxidation of thiamine to thiochrome in the presence of trace ferrocyanide. RSC Advances, 4 (12): (5990-5994). [PMID:] [10.1039/C3RA46170J]

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