Determine the necessary mass, volume, or concentration for preparing a solution.
Basic Description
| Synonyms | THIAMINE HYDROCHLORIDE | 67-03-8 | Thiamine HCL | Aneurine hydrochloride | Vitamin B1 hydrochloride | Clotiamina | Eskaphen | Thiamine chloride hydrochloride | Betalin S | Thiamine dichloride | vitamin B1 | Begiolan | Bethiazine | Bevitine | Bithiamin | Thiadoxine | Tiamidon | Tiaminal | Vi |
|---|---|
| Specifications & Purity | 10mM in Water |
| Biochemical and Physiological Mechanisms | Vitamin cofactor. Enables cellular oxidation of carbohydrates and synthesis of ribose. Shows neuroprotective and hepatoprotective effects in vivo. Orally active. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Thiamine or vitamin B1 is a water-soluble vitamin of the B complex, its phosphate derivatives are involved in many cellular processes.Thiamine is a water-soluble vitamin-B complex. Structurally, it possesses a five-membered thiazolium ring and a six-membered amino-pyrimidine ring connected by a methyl group. Thiamine is naturally available in fruits, vegetables, poultry, eggs. |
AI Insight
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol;chloride;hydrochloride |
|---|---|
| INCHI | InChI=1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1 |
| InChi Key | DPJRMOMPQZCRJU-UHFFFAOYSA-M |
| Canonical SMILES | CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-] |
| Isomeric SMILES | CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-] |
| WGK Germany | 1 |
| RTECS | XI7350000 |
| Alternate CAS | 59-43-8 |
| PubChem CID | 6202 |
| Molecular Weight | 337.27 |
| Beilstein | 3851771 |
| Reaxy-Rn | 3851771 |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |
| WGK Germany | 1 |
| RTECS | XI7350000 |
| Reaxy-Rn | 3851771 |
| Merck Index | 9295 |
Related Documents
Reviews
Customer Reviews
Citations of This Product
| 1. Taoyue Yuan, Shunke Ding, Fei Xue, Zhenqi Du, Xinyu Yang, Qingzhi Han, Mengtao Ma, Xiaoyan Chen. (2024) Reactivity and reaction pathways of peroxymonosulfate and peroxydisulfate with neonicotinoid insecticides. WATER RESEARCH, 248 (120852). [PMID:37976950] [10.1016/j.watres.2023.120852] |
| 2. Yuelong Xu, Jingyue Wang, Shasha Wang, Zuozhao Zhai, Bin Ren, Zhi Tian, Lihui Zhang, Zhenfa Liu. (2023) Lattice defective and N, S co-doped carbon nanotubes for trifunctional electrocatalyst application. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 48 (34340). [PMID:] [10.1016/j.ijhydene.2023.05.189] |
| 3. Yu Fan, Xin Wang, He Huang, Yumeng Yang, Jinlin Guo, Shajie Luo, Meilian Zhao, Yang Li. (2023) A visual ratiometric fluorescence sensor for glutathione response based on MnO2 nanowires as an oxidant, quencher and recognition unit. Analytical Methods, 15 (4): (419-429). [PMID:36606523] [10.1039/D2AY01812H] |
| 4. Zhang Jing-Xian, Lv Chun-Lin, Tang Chang, Jiang Lu-Yao, Wang Ai-Jun, Feng Jiu-Ju. (2022) Ultrasensitive sandwich-typed electrochemical immunoassay for detection of squamous cell carcinoma antigen based on highly branched PtCo nanocrystals and dendritic mesoporous SiO2@AuPt nanoparticles. MICROCHIMICA ACTA, 189 (11): (1-11). [PMID:36219254] [10.1007/s00604-022-05520-1] |
| 5. Yanshen Nie, Li Yu, Lianlian Mao, Wenxuan Zou, Xiufeng Zhang, Jie Zhao. (2022) Vitamin B1 THIAMIN REQUIRING1 synthase mediates the maintenance of chloroplast function by regulating sugar and fatty acid metabolism in rice. Journal of Integrative Plant Biology, 64 (8): (1575-1595). [PMID:35603832] [10.1111/jipb.13283] |
| 6. Yi Ma, Mawda Elmhadi, Chao Wang, Hao Zhang, Hongrong Wang. (2021) Dietary supplementation of thiamine down-regulates the expression of mitophagy and endoplasmic reticulum stress-related genes in the rumen epithelium of goats during high-concentrate diet feeding. Italian Journal of Animal Science, 20 (1): (2220-2231). [PMID:] [10.1080/1828051X.2021.1985944] |
| 7. Naymul Karim, Mohammad Rezaul Islam Shishir, Tao Bao, Wei Chen. (2021) Effect of cold plasma pretreated hot-air drying on the physicochemical characteristics, nutritional values and antioxidant activity of shiitake mushroom. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (15): (6271-6280). [PMID:33949697] [10.1002/jsfa.11296] |
| 8. Linyu Wang, Yi Xie, Yuxi Yang, Huihui Liang, Li Wang, Yonghai Song. (2020) Electroactive Covalent Organic Frameworks/Carbon Nanotubes Composites for Electrochemical Sensing. ACS Applied Nano Materials, 3 (2): (1412–1419). [PMID:] [10.1021/acsanm.9b02257] |
| 9. Pengjuan Ni, Dafeng Jiang, Chuanxia Chen, Yuanyuan Jiang, Yizhong Lu, Zhenlu Zhao. (2018) Highly sensitive fluorescent detection of glutathione and histidine based on the Cu(II)-thiamine system. ANALYST, 143 (18): (4442-4447). [PMID:30151530] [10.1039/C8AN01201F] |
| 10. Xiaona Li, Dandan Han, Yan Wang, Shichao Du, Yumin Liu, Jiaqi Zhang, Bo Yu, Baohong Hou, Junbo Gong. (2016) Measurement of Solubility of Thiamine Hydrochloride Hemihydrate in Three Binary Solvents and Mixing Properties of Solutions. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 61 (10): (3665–3678). [PMID:] [10.1021/acs.jced.6b00613] |
| 11. Ying Li, Changyin Lv, Qiang Sun, Ying Zhao, Yunjing Li. (2014) Chromatographic characteristics of water-soluble vitamins with irradiation processing and its application. Analytical Methods, 7 (1): (155-160). [PMID:] [10.1039/C4AY01312C] |
| 12. Jinghui Zhu, Shaopu Liu, Zhongfang Liu, Yuanfang Li, Man Qiao, Xiaoli Hu. (2014) Enhanced spectrofluorimetric determination of hypochlorite based on the catalytic oxidation of thiamine to thiochrome in the presence of trace ferrocyanide. RSC Advances, 4 (12): (5990-5994). [PMID:] [10.1039/C3RA46170J] |
References
| 1. Taoyue Yuan, Shunke Ding, Fei Xue, Zhenqi Du, Xinyu Yang, Qingzhi Han, Mengtao Ma, Xiaoyan Chen. (2024) Reactivity and reaction pathways of peroxymonosulfate and peroxydisulfate with neonicotinoid insecticides. WATER RESEARCH, 248 (120852). [PMID:37976950] [10.1016/j.watres.2023.120852] |
| 2. Yuelong Xu, Jingyue Wang, Shasha Wang, Zuozhao Zhai, Bin Ren, Zhi Tian, Lihui Zhang, Zhenfa Liu. (2023) Lattice defective and N, S co-doped carbon nanotubes for trifunctional electrocatalyst application. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 48 (34340). [PMID:] [10.1016/j.ijhydene.2023.05.189] |
| 3. Yu Fan, Xin Wang, He Huang, Yumeng Yang, Jinlin Guo, Shajie Luo, Meilian Zhao, Yang Li. (2023) A visual ratiometric fluorescence sensor for glutathione response based on MnO2 nanowires as an oxidant, quencher and recognition unit. Analytical Methods, 15 (4): (419-429). [PMID:36606523] [10.1039/D2AY01812H] |
| 4. Zhang Jing-Xian, Lv Chun-Lin, Tang Chang, Jiang Lu-Yao, Wang Ai-Jun, Feng Jiu-Ju. (2022) Ultrasensitive sandwich-typed electrochemical immunoassay for detection of squamous cell carcinoma antigen based on highly branched PtCo nanocrystals and dendritic mesoporous SiO2@AuPt nanoparticles. MICROCHIMICA ACTA, 189 (11): (1-11). [PMID:36219254] [10.1007/s00604-022-05520-1] |
| 5. Yanshen Nie, Li Yu, Lianlian Mao, Wenxuan Zou, Xiufeng Zhang, Jie Zhao. (2022) Vitamin B1 THIAMIN REQUIRING1 synthase mediates the maintenance of chloroplast function by regulating sugar and fatty acid metabolism in rice. Journal of Integrative Plant Biology, 64 (8): (1575-1595). [PMID:35603832] [10.1111/jipb.13283] |
| 6. Yi Ma, Mawda Elmhadi, Chao Wang, Hao Zhang, Hongrong Wang. (2021) Dietary supplementation of thiamine down-regulates the expression of mitophagy and endoplasmic reticulum stress-related genes in the rumen epithelium of goats during high-concentrate diet feeding. Italian Journal of Animal Science, 20 (1): (2220-2231). [PMID:] [10.1080/1828051X.2021.1985944] |
| 7. Naymul Karim, Mohammad Rezaul Islam Shishir, Tao Bao, Wei Chen. (2021) Effect of cold plasma pretreated hot-air drying on the physicochemical characteristics, nutritional values and antioxidant activity of shiitake mushroom. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (15): (6271-6280). [PMID:33949697] [10.1002/jsfa.11296] |
| 8. Linyu Wang, Yi Xie, Yuxi Yang, Huihui Liang, Li Wang, Yonghai Song. (2020) Electroactive Covalent Organic Frameworks/Carbon Nanotubes Composites for Electrochemical Sensing. ACS Applied Nano Materials, 3 (2): (1412–1419). [PMID:] [10.1021/acsanm.9b02257] |
| 9. Pengjuan Ni, Dafeng Jiang, Chuanxia Chen, Yuanyuan Jiang, Yizhong Lu, Zhenlu Zhao. (2018) Highly sensitive fluorescent detection of glutathione and histidine based on the Cu(II)-thiamine system. ANALYST, 143 (18): (4442-4447). [PMID:30151530] [10.1039/C8AN01201F] |
| 10. Xiaona Li, Dandan Han, Yan Wang, Shichao Du, Yumin Liu, Jiaqi Zhang, Bo Yu, Baohong Hou, Junbo Gong. (2016) Measurement of Solubility of Thiamine Hydrochloride Hemihydrate in Three Binary Solvents and Mixing Properties of Solutions. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 61 (10): (3665–3678). [PMID:] [10.1021/acs.jced.6b00613] |
| 11. Ying Li, Changyin Lv, Qiang Sun, Ying Zhao, Yunjing Li. (2014) Chromatographic characteristics of water-soluble vitamins with irradiation processing and its application. Analytical Methods, 7 (1): (155-160). [PMID:] [10.1039/C4AY01312C] |
| 12. Jinghui Zhu, Shaopu Liu, Zhongfang Liu, Yuanfang Li, Man Qiao, Xiaoli Hu. (2014) Enhanced spectrofluorimetric determination of hypochlorite based on the catalytic oxidation of thiamine to thiochrome in the presence of trace ferrocyanide. RSC Advances, 4 (12): (5990-5994). [PMID:] [10.1039/C3RA46170J] |