Basic Description

Synonyms	Lixa-beta \| Thiamine chloride, hydrochloride \| Thiamine for system suitability \| THIAMINE HYDROCHLORIDE (EP MONOGRAPH) \| Thiamine, chloride, hydrochloride \| thymine hydrochloride \| UNII-M572600E5P \| NCGC00017013-01 \| Bevitine \| Thiamin dichloride \| Thiami
Specifications & Purity	PharmPure™, USP
Storage Temp	Argon charged
Shipped In	Normal
Grade	PharmPure™, USP
Mechanism of action	Supplement

AI Insight

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol;chloride;hydrochloride
INCHI	InChI=1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
InChi Key	DPJRMOMPQZCRJU-UHFFFAOYSA-M
Canonical SMILES	CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
Isomeric SMILES	CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-]
WGK Germany	1
RTECS	XI7350000
Alternate CAS	59-43-8
PubChem CID	6202
Molecular Weight	337.27
Beilstein	3851771
Reaxy-Rn	3851771

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number	Certificate Type	Date	Item
F2103362	Certificate of Analysis	Mar 04, 2025	T104102
H2421047	Certificate of Analysis	Aug 27, 2024	T104102
J2227728	Certificate of Analysis	Nov 01, 2022	T104102
C2201023	Certificate of Analysis	Mar 14, 2022	T104102

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
WGK Germany	1
RTECS	XI7350000
Reaxy-Rn	3851771
Merck Index	9295

Reviews

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Taoyue Yuan, Shunke Ding, Fei Xue, Zhenqi Du, Xinyu Yang, Qingzhi Han, Mengtao Ma, Xiaoyan Chen. (2024) Reactivity and reaction pathways of peroxymonosulfate and peroxydisulfate with neonicotinoid insecticides. WATER RESEARCH, 248 (120852). [PMID:37976950] [10.1016/j.watres.2023.120852]
2. Yuelong Xu, Jingyue Wang, Shasha Wang, Zuozhao Zhai, Bin Ren, Zhi Tian, Lihui Zhang, Zhenfa Liu. (2023) Lattice defective and N, S co-doped carbon nanotubes for trifunctional electrocatalyst application. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 48 (34340). [PMID:] [10.1016/j.ijhydene.2023.05.189]
3. Yu Fan, Xin Wang, He Huang, Yumeng Yang, Jinlin Guo, Shajie Luo, Meilian Zhao, Yang Li. (2023) A visual ratiometric fluorescence sensor for glutathione response based on MnO2 nanowires as an oxidant, quencher and recognition unit. Analytical Methods, 15 (4): (419-429). [PMID:36606523] [10.1039/D2AY01812H]
4. Zhang Jing-Xian, Lv Chun-Lin, Tang Chang, Jiang Lu-Yao, Wang Ai-Jun, Feng Jiu-Ju. (2022) Ultrasensitive sandwich-typed electrochemical immunoassay for detection of squamous cell carcinoma antigen based on highly branched PtCo nanocrystals and dendritic mesoporous SiO2@AuPt nanoparticles. MICROCHIMICA ACTA, 189 (11): (1-11). [PMID:36219254] [10.1007/s00604-022-05520-1]
5. Yanshen Nie, Li Yu, Lianlian Mao, Wenxuan Zou, Xiufeng Zhang, Jie Zhao. (2022) Vitamin B1 THIAMIN REQUIRING1 synthase mediates the maintenance of chloroplast function by regulating sugar and fatty acid metabolism in rice. Journal of Integrative Plant Biology, 64 (8): (1575-1595). [PMID:35603832] [10.1111/jipb.13283]
6. Yi Ma, Mawda Elmhadi, Chao Wang, Hao Zhang, Hongrong Wang. (2021) Dietary supplementation of thiamine down-regulates the expression of mitophagy and endoplasmic reticulum stress-related genes in the rumen epithelium of goats during high-concentrate diet feeding. Italian Journal of Animal Science, 20 (1): (2220-2231). [PMID:] [10.1080/1828051X.2021.1985944]
7. Naymul Karim, Mohammad Rezaul Islam Shishir, Tao Bao, Wei Chen. (2021) Effect of cold plasma pretreated hot-air drying on the physicochemical characteristics, nutritional values and antioxidant activity of shiitake mushroom. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (15): (6271-6280). [PMID:33949697] [10.1002/jsfa.11296]
8. Linyu Wang, Yi Xie, Yuxi Yang, Huihui Liang, Li Wang, Yonghai Song. (2020) Electroactive Covalent Organic Frameworks/Carbon Nanotubes Composites for Electrochemical Sensing. ACS Applied Nano Materials, 3 (2): (1412–1419). [PMID:] [10.1021/acsanm.9b02257]
9. Pengjuan Ni, Dafeng Jiang, Chuanxia Chen, Yuanyuan Jiang, Yizhong Lu, Zhenlu Zhao. (2018) Highly sensitive fluorescent detection of glutathione and histidine based on the Cu(II)-thiamine system. ANALYST, 143 (18): (4442-4447). [PMID:30151530] [10.1039/C8AN01201F]
10. Xiaona Li, Dandan Han, Yan Wang, Shichao Du, Yumin Liu, Jiaqi Zhang, Bo Yu, Baohong Hou, Junbo Gong. (2016) Measurement of Solubility of Thiamine Hydrochloride Hemihydrate in Three Binary Solvents and Mixing Properties of Solutions. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 61 (10): (3665–3678). [PMID:] [10.1021/acs.jced.6b00613]
11. Ying Li, Changyin Lv, Qiang Sun, Ying Zhao, Yunjing Li. (2014) Chromatographic characteristics of water-soluble vitamins with irradiation processing and its application. Analytical Methods, 7 (1): (155-160). [PMID:] [10.1039/C4AY01312C]
12. Jinghui Zhu, Shaopu Liu, Zhongfang Liu, Yuanfang Li, Man Qiao, Xiaoli Hu. (2014) Enhanced spectrofluorimetric determination of hypochlorite based on the catalytic oxidation of thiamine to thiochrome in the presence of trace ferrocyanide. RSC Advances, 4 (12): (5990-5994). [PMID:] [10.1039/C3RA46170J]

References

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5. Sándor Gonda,Attila Kiss-Szikszai,Zsolt Szűcs,Csaba Máthé,Gábor Vasas. (2014-08-02) Effects of N source concentration and NH4(+)/NO3(-) ratio on phenylethanoid glycoside pattern in tissue cultures of Plantago lanceolata L.: a metabolomics driven full-factorial experiment with LC-ESI-MS(3.).. Phytochemistry, 106 (44-54). [PMID:25081104]
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9. Katherine R Heal,Laura Truxal Carlson,Allan H Devol,E Virginia Armbrust,James W Moffett,David A Stahl,Anitra E Ingalls. (2014-10-11) Determination of four forms of vitamin B12 and other B vitamins in seawater by liquid chromatography/tandem mass spectrometry.. Rapid communications in mass spectrometry : RCM, 28 ((22)): (2398-2404). [PMID:25303468]
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13. Marcela Cristina de Moraes,Juliana Bosco Santos,Daniel Meira Dos Anjos,Luciana Pereira Rangel,Tuane Cristine Ramos Gonçalves Vieira,Ruin Moaddel,Jerson Lima da Silva. (2015-01-13) Prion protein-coated magnetic beads: synthesis, characterization and development of a new ligands screening method.. Journal of chromatography. A, 1379 (1-8). [PMID:25576041]
14. Nicholas Fowler,Carmelo Tomas,Daniel Baden,Lisa Campbell,Andrea Bourdelais. (2015-05-20) Chemical analysis of Karenia papilionacea.. Toxicon : official journal of the International Society on Toxinology, 101 (85-91). [PMID:25981346]
15. Kris Niño G Valdehuesa,Won-Keun Lee,Kristine Rose M Ramos,Rhudith B Cabulong,JiSoo Choi,Huaiwei Liu,Grace M Nisola,Wook-Jin Chung. (2015-06-07) Identification of aldehyde reductase catalyzing the terminal step for conversion of xylose to butanetriol in engineered Escherichia coli.. Bioprocess and biosystems engineering, 38 ((9)): (1761-1772). [PMID:26048478]
16. Kangming Tian,Dandan Niu,Xiaoguang Liu,Bernard A Prior,Li Zhou,Fuping Lu,Suren Singh,Zhengxiang Wang. (2015-07-15) Limitation of thiamine pyrophosphate supply to growing Escherichia coli switches metabolism to efficient D-lactate formation.. Biotechnology and bioengineering, 113 ((1)): (182-188). [PMID:26152364]
17. Vishnupriya Pradeep,Steven W Van Ginkel,Sichoon Park,Thomas Igou,Christine Yi,Hao Fu,Rachel Johnston,Terry Snell,Yongsheng Chen. (2015-09-26) Use of Copper to Selectively Inhibit Brachionus calyciflorus (Predator) Growth in Chlorella kessleri (Prey) Mass Cultures for Algae Biodiesel Production.. International journal of molecular sciences, 16 ((9)): (20674-20684). [PMID:26404247]
18. Lindsey C Vedder,Joseph M Hall,Kimberly R Jabrouin,Lisa M Savage. (2015-10-01) Interactions between chronic ethanol consumption and thiamine deficiency on neural plasticity, spatial memory, and cognitive flexibility.. Alcoholism, clinical and experimental research, 39 ((11)): (2143-2153). [PMID:26419807]
19. G Apodaca,J H McKerrow. (1989-10-01) Regulation of Trichophyton rubrum proteolytic activity.. Infection and immunity, 57 ((10)): (3081-3090). [PMID:2476398]
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21. Samir Ahmed El-Shazly,Mohamed Mohamed Ahmed,Zein Shaban Ibrahim,Moamen S Refat. (2015-03-31) Synthesis, characterization, and efficacy evaluation of a new anti-diabetic vanadyl(II) thiamine hydrochloride complex in streptozotocin-induced diabetic rats.. International journal of immunopathology and pharmacology, 28 ((2)): (227-239). [PMID:25816395]
22. Carlos A Mora,Antoine F Herzog,Renzo A Raso,Wendelin J Stark. (2015-05-20) Programmable living material containing reporter micro-organisms permits quantitative detection of oligosaccharides.. Biomaterials, 61 (1-9). [PMID:25988843]
23. Taoyue Yuan, Shunke Ding, Fei Xue, Zhenqi Du, Xinyu Yang, Qingzhi Han, Mengtao Ma, Xiaoyan Chen. (2024) Reactivity and reaction pathways of peroxymonosulfate and peroxydisulfate with neonicotinoid insecticides. WATER RESEARCH, 248 (120852). [PMID:37976950] [10.1016/j.watres.2023.120852]
24. Yuelong Xu, Jingyue Wang, Shasha Wang, Zuozhao Zhai, Bin Ren, Zhi Tian, Lihui Zhang, Zhenfa Liu. (2023) Lattice defective and N, S co-doped carbon nanotubes for trifunctional electrocatalyst application. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 48 (34340). [PMID:] [10.1016/j.ijhydene.2023.05.189]
25. Yu Fan, Xin Wang, He Huang, Yumeng Yang, Jinlin Guo, Shajie Luo, Meilian Zhao, Yang Li. (2023) A visual ratiometric fluorescence sensor for glutathione response based on MnO2 nanowires as an oxidant, quencher and recognition unit. Analytical Methods, 15 (4): (419-429). [PMID:36606523] [10.1039/D2AY01812H]
26. Zhang Jing-Xian, Lv Chun-Lin, Tang Chang, Jiang Lu-Yao, Wang Ai-Jun, Feng Jiu-Ju. (2022) Ultrasensitive sandwich-typed electrochemical immunoassay for detection of squamous cell carcinoma antigen based on highly branched PtCo nanocrystals and dendritic mesoporous SiO2@AuPt nanoparticles. MICROCHIMICA ACTA, 189 (11): (1-11). [PMID:36219254] [10.1007/s00604-022-05520-1]
27. Yanshen Nie, Li Yu, Lianlian Mao, Wenxuan Zou, Xiufeng Zhang, Jie Zhao. (2022) Vitamin B1 THIAMIN REQUIRING1 synthase mediates the maintenance of chloroplast function by regulating sugar and fatty acid metabolism in rice. Journal of Integrative Plant Biology, 64 (8): (1575-1595). [PMID:35603832] [10.1111/jipb.13283]
28. Yi Ma, Mawda Elmhadi, Chao Wang, Hao Zhang, Hongrong Wang. (2021) Dietary supplementation of thiamine down-regulates the expression of mitophagy and endoplasmic reticulum stress-related genes in the rumen epithelium of goats during high-concentrate diet feeding. Italian Journal of Animal Science, 20 (1): (2220-2231). [PMID:] [10.1080/1828051X.2021.1985944]
29. Naymul Karim, Mohammad Rezaul Islam Shishir, Tao Bao, Wei Chen. (2021) Effect of cold plasma pretreated hot-air drying on the physicochemical characteristics, nutritional values and antioxidant activity of shiitake mushroom. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (15): (6271-6280). [PMID:33949697] [10.1002/jsfa.11296]
30. Linyu Wang, Yi Xie, Yuxi Yang, Huihui Liang, Li Wang, Yonghai Song. (2020) Electroactive Covalent Organic Frameworks/Carbon Nanotubes Composites for Electrochemical Sensing. ACS Applied Nano Materials, 3 (2): (1412–1419). [PMID:] [10.1021/acsanm.9b02257]
31. Pengjuan Ni, Dafeng Jiang, Chuanxia Chen, Yuanyuan Jiang, Yizhong Lu, Zhenlu Zhao. (2018) Highly sensitive fluorescent detection of glutathione and histidine based on the Cu(II)-thiamine system. ANALYST, 143 (18): (4442-4447). [PMID:30151530] [10.1039/C8AN01201F]
32. Xiaona Li, Dandan Han, Yan Wang, Shichao Du, Yumin Liu, Jiaqi Zhang, Bo Yu, Baohong Hou, Junbo Gong. (2016) Measurement of Solubility of Thiamine Hydrochloride Hemihydrate in Three Binary Solvents and Mixing Properties of Solutions. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 61 (10): (3665–3678). [PMID:] [10.1021/acs.jced.6b00613]
33. Ying Li, Changyin Lv, Qiang Sun, Ying Zhao, Yunjing Li. (2014) Chromatographic characteristics of water-soluble vitamins with irradiation processing and its application. Analytical Methods, 7 (1): (155-160). [PMID:] [10.1039/C4AY01312C]
34. Jinghui Zhu, Shaopu Liu, Zhongfang Liu, Yuanfang Li, Man Qiao, Xiaoli Hu. (2014) Enhanced spectrofluorimetric determination of hypochlorite based on the catalytic oxidation of thiamine to thiochrome in the presence of trace ferrocyanide. RSC Advances, 4 (12): (5990-5994). [PMID:] [10.1039/C3RA46170J]

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Thiamine hydrochloride - USP, high purity , Supplement, CAS No.67-03-8, Supplement