Porous Graphitic Carbon (PGC) Chromatography Columns: Creating New Selectivity for Challenging Separations through Molecular Shape and the π-Electron Cloud on the Graphitic Surface
In high-performance liquid chromatography (High Performance Liquid Chromatography, HPLC), octadecylsilane-bonded stationary phase (Octadecylsilane, C18) is the most commonly used reversed-phase stationary phase. The main separation basis of C18 is hydrophobic partitioning: the more hydrophobic a ...