Topic: Fluorination Reagent

Articles by Topic "Fluorination Reagent"

Knowledge Base
Technical articles

Synthesis Strategy of Pentafluorothio Group - Synthesis of Aliphatic Compounds Containing SF₅

The pentafluorosulfanyl (SF₅) group, as a unique fluorine-containing functional group, has demonstrated broad application prospects in medicinal chemistry, materials science, and other fields due to its excellent chemical stability, high electronegativity, and lipophilicity. In recent years, ...

Updated Jul 20258 min read ✓ Reviewed
Technical articles

Synthesis Strategy of Pentafluorothio Group - Synthesis of Aromatic Compounds Containing SF₅

In 2015, the Dolbier group reported a method where phenylacetylene is used as the substrate, reacting with SF₅Cl under the catalysis of triethylborane (BEt₃) to generate a chlorinated pentafluorosulfanylated intermediate (189).

Updated Jul 20258 min read ✓ Reviewed
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