| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| P275736-50mg | 50mg | 5 | $53.90 | |
| P275736-250mg | 250mg | 1 | $243.90 |
D 2 -receptor antagonist, antipsychotic agent
| Synonyms | Orap | R6238 | MLS000028410 | Pimozidum | PIMOZIDE [USP MONOGRAPH] | Prestwick0_000308 | HMS501D08 | Opiran | BSPBio_001439 | GTPL90 | KBio2_006061 | Pimozide (USAN:USP:INN:BAN:JAN) | Prestwick2_000308 | 5-24-02-00367 (Beilstein Handbook Reference) | Lopa |
|---|---|
| Specifications & Purity | Moligand™, ≥98% |
| Biochemical and Physiological Mechanisms | D 2 -receptor antagonist. Antipsychotic agent. Binds with high affinity to the 5-HT 7 receptor (K i = 0.5 nM). Decrease STAT5 tyrosine phosphorylation. |
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| Grade | Moligand™ |
| Action Type | ANTAGONIST, CHANNEL BLOCKER, GATING INHIBITOR |
| Mechanism of action | Dopamine receptor antagonist |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| ALogP | 6.3 |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 504752750 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504752750 |
| IUPAC Name | 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one |
| INCHI | InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) |
| InChi Key | YVUQSNJEYSNKRX-UHFFFAOYSA-N |
| Canonical SMILES | C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F |
| Isomeric SMILES | C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F |
| PubChem CID | 16362 |
| Molecular Weight | 461.55 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2401087 | Certificate of Analysis | Jul 09, 2024 | P275736 |
| E2305476 | Certificate of Analysis | Mar 07, 2024 | P275736 |
| E2305472 | Certificate of Analysis | Mar 07, 2024 | P275736 |
| E2305499 | Certificate of Analysis | Feb 23, 2024 | P275736 |
| E2305437 | Certificate of Analysis | Apr 15, 2023 | P275736 |
| K2329189 | Certificate of Analysis | Apr 15, 2023 | P275736 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H302:Harmful if swallowed |
| Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
Starting at $103.90
