| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| P422505-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $103.90 |
D 2 -receptor antagonist, antipsychotic agent
| Synonyms | MLS000028410 | Pimozidum | PIMOZIDE [USP MONOGRAPH] | Prestwick0_000308 | HMS501D08 | Opiran | BSPBio_001439 | GTPL90 | KBio2_006061 | Pimozide (USAN:USP:INN:BAN:JAN) | Prestwick2_000308 | 5-24-02-00367 (Beilstein Handbook Reference) | Lopac0_000946 | NSC |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | D 2 -receptor antagonist. Antipsychotic agent. Binds with high affinity to the 5-HT 7 receptor (K i = 0.5 nM). Decrease STAT5 tyrosine phosphorylation. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Action Type | ANTAGONIST, CHANNEL BLOCKER, GATING INHIBITOR |
| Mechanism of action | Dopamine receptor antagonist |
| ALogP | 6.3 |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one |
|---|---|
| INCHI | InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) |
| InChi Key | YVUQSNJEYSNKRX-UHFFFAOYSA-N |
| Canonical SMILES | C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F |
| Isomeric SMILES | C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F |
| PubChem CID | 16362 |
| Molecular Weight | 461.55 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H302:Harmful if swallowed |
| Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
