| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A104524-25g | 25g | 3 | $19.90 | |
| A104524-100g | 100g | 3 | $71.90 | |
| A104524-250g | 250g | 2 | $161.90 | |
| A104524-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $290.90 |
| Synonyms | ASCORBYL PALMITATE [II] | Ins no.304 | ASCORBYL PALMITATE | Ascorbylpalmitic acid | MFCD00865068 | CAS-137-66-6 | DTXSID3041611 | Nitaxozanid | 6-O-Palmitoyl-L-ascorbic acid | ASCORBYL PALMITATE [MART.] | A0540 | 6-Palmitoyl-L-ascorbic acid | QN83US2B0N | |
|---|---|
| Specifications & Purity | ≥99% |
| Biochemical and Physiological Mechanisms | L-Ascorbyl palmitate (Asc-6P) is used along with other fatty acid ascorbates such as L-ascorbyl oleate and L-ascorbyl linoleate to protect cells and membranes from oxidative damage. Fatty acid ascorbate molecules have increased solubility in non-polar (li |
| Shipped In | Normal |
| Product Description | Product Application: L-Ascorbyl palmitate (Asc-6P) is used along with other fatty acid ascorbates such as L-ascorbyl oleate and L-ascorbyl linoleate to protect cells and membranes from oxidative damage. Fatty acid ascorbate molecules have increased solubility in non-polar (lipophilic) environments. It is applied as humectants and emollients. |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 488201691 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488201691 |
| IUPAC Name | [(2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2H-furan-2-yl]-2-hydroxyethyl] hexadecanoate |
| INCHI | InChI=1S/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,21,23,25-26H,2-16H2,1H3/t17-,21+/m0/s1 |
| InChi Key | QAQJMLQRFWZOBN-LAUBAEHRSA-N |
| Canonical SMILES | CCCCCCCCCCCCCCCC(=O)OCC(C1C(=C(C(=O)O1)O)O)O |
| Isomeric SMILES | CCCCCCCCCCCCCCCC(=O)OC[C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O |
| WGK Germany | 1 |
| PubChem CID | 54680660 |
| Molecular Weight | 414.53 |
| Beilstein | 96552 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2416551 | Certificate of Analysis | Apr 29, 2024 | A104524 |
| G2416552 | Certificate of Analysis | Apr 29, 2024 | A104524 |
| G2416554 | Certificate of Analysis | Apr 29, 2024 | A104524 |
| H2308688 | Certificate of Analysis | May 24, 2023 | A104524 |
| H2308690 | Certificate of Analysis | May 24, 2023 | A104524 |
| H2308691 | Certificate of Analysis | May 24, 2023 | A104524 |
| H2308693 | Certificate of Analysis | May 24, 2023 | A104524 |
| B2310303 | Certificate of Analysis | Feb 16, 2023 | A104524 |
| B2219248 | Certificate of Analysis | Feb 23, 2022 | A104524 |
| B2219306 | Certificate of Analysis | Feb 23, 2022 | A104524 |
| B2219316 | Certificate of Analysis | Feb 23, 2022 | A104524 |
| B2219317 | Certificate of Analysis | Feb 23, 2022 | A104524 |
| E2304428 | Certificate of Analysis | Feb 23, 2022 | A104524 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H319:Causes serious eye irritation H412:Harmful to aquatic life with long lasting effects |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. |
| WGK Germany | 1 |
Starting at $50.90
Starting at $69.90
| 1. Ziwei Wang, Fujun Liu, Ying Luo, Xiangbo Zeng, Xuechen Pei, Guanhua Zhao, Min Zhang, Dayong Zhou, Fawen Yin. (2022) Effects of Tea Polyphenol and Its Combination with Other Antioxidants Added during the Extraction Process on Oxidative Stability of Antarctic Krill (Euphausia superba) Oil. Foods, 11 (23): (3768). [PMID:36496576] [10.3390/foods11233768] |
| 2. Yuling Li, Xiaotong Wu, Zixuan Wu, Mingmin Zhong, Xiaoping Su, Youai Ye, Yan Liu, Lei Tan, Yong Liang. (2022) Colorimetric sensor array based on CoOOH nanoflakes for rapid discrimination of antioxidants in food. Analytical Methods, 14 (28): (2754-2760). [PMID:35781305] [10.1039/D2AY00692H] |
| 3. Sun Dongdong, Wang Zekun, Zhang Pu, Yin Chenyang, Wang Jingyuan, Sun Yu, Chen Ying, Wang Weiyun, Sun Baoliang, Fan Cundong. (2021) Ruthenium-loaded mesoporous silica as tumor microenvironment-response nano-fenton reactors for precise cancer therapy. JOURNAL OF NANOBIOTECHNOLOGY, 19 (1): (1-16). [PMID:33827604] [10.1186/s12951-021-00848-x] |
| 4. Shujie Wang, Guoqin Liu, Weiwei Cheng. (2021) Comparative evaluation of four free radical scavengers for the inhibition of individual glycidyl ester formation in rice bran oil determined by UPLC-MS/MS. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 56 (6): (2983-2991). [PMID:] [10.1111/ijfs.14941] |
| 5. Junhua Li, Yimei Shen, Jiali Zhai, Yujie Su, Luping Gu, Cuihua Chang, Yanjun Yang. (2021) Enhancing the oxidative stability of algal oil powders stabilized by egg yolk granules/lecithin composites. FOOD CHEMISTRY, 345 (128782). [PMID:33302099] [10.1016/j.foodchem.2020.128782] |
| 6. Chang Li,Hanbing Jia,Mingyue Shen,Yuting Wang,Shaoping Nie,Yi Chen,Yongqiang Zhou,Yuanxing Wang,Mingyong Xie. (2015-10-20) Antioxidants Inhibit Formation of 3-Monochloropropane-1,2-diol Esters in Model Reactions.. Journal of agricultural and food chemistry, 63 ((44)): (9850-9854). [PMID:26478126] |
| 1. Qing-Xun Song,Dong-Zhi Wei,Wen-Yu Zhou,Wei-Qin Xu,Sheng-Li Yang. (2005-01-27) Enzymatic synthesis and antioxidant properties of L-ascorbyl oleate and L-ascorbyl linoleate.. Biotechnology letters, 26 ((23)): (1777-1780). [PMID:15672213] |
| 2. Karl-Heinz Wagner,Patrick Feigl,Ibrahim Elmadfa. (2005-04-06) Ascorbyl palmitate and its synergism to tocopherols.. Forum of nutrition, 56 (347-348). [PMID:15806929] |
| 3. Gopa Mitra,P K Mukhopadhyay,S Ayyappan. (2008-03-11) Modulation of digestive enzyme activities during ontogeny of Labeo rohita larvae fed ascorbic acid enriched zooplankton.. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 149 ((4)): (341-350). [PMID:18329933] |
| 4. Michelle Olsher,Parkson Lee-Gau Chong. (2008-08-13) Sterol superlattice affects antioxidant potency and can be used to assess adverse effects of antioxidants.. Analytical biochemistry, 382 ((1)): (1-8). [PMID:18694720] |
| 5. J H Han,H-M Hwang,S Min,J M Krochta. (2008-11-21) Coating of peanuts with edible whey protein film containing alpha-tocopherol and ascorbyl palmitate.. Journal of food science, 73 ((8)): (E349-E355). [PMID:19019105] |
| 6. Kyung Mi Lee,Jung Yeon Kwon,Ki Won Lee,Hyong Joo Lee. (2008-11-26) Ascorbic acid 6-palmitate suppresses gap-junctional intercellular communication through phosphorylation of connexin 43 via activation of the MEK-ERK pathway.. Mutation research, 660 ((1-2)): (51-56). [PMID:19026667] |
| 7. Yohko Kuge,Ayato Kanda,Setsuko Hara. (2009-05-12) Pursuit of oxidation behavior for conjugated polyenoyl glycerols and establishment of their novel oxidation prevention method.. Journal of oleo science, 58 ((6)): (295-301). [PMID:19430191] |
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| 9. Mayura Wittayasuporn,Sirirat Rengpipat,Tanapat Palaga,Pravit Asawanonda,Nattaporn Anumansirikul,Supasorn P Wanichwecharungruang. (2009-07-02) Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation.. Journal of microencapsulation, 27 ((3)): (218-225). [PMID:19566395] |
| 10. Kazufusa Shinomiya,Heran Li,Susumu Kitanaka,Yoichiro Ito. (2010-01-05) Countercurrent Chromatographic Separation of Lipophilic Ascorbic Acid Derivatives and Extract from Kadsura Coccinea Using Hydrophobic Organic-Aqueous Two-Phase Solvent Systems.. Journal of liquid chromatography & related technologies, 32 ((16)): (2361-2371). [PMID:20046934] |
| 11. Charlotte Jacobsen. (2010-04-15) Enrichment of foods with omega-3 fatty acids: a multidisciplinary challenge.. Annals of the New York Academy of Sciences, 1190 (141-150). [PMID:20388145] |
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| 13. Raju Jukanti,Gopinath Devraj,Apte S Shashank,Rambhau Devraj. (2011-01-27) Biodistribution of ascorbyl palmitate loaded doxorubicin pegylated liposomes in solid tumor bearing mice.. Journal of microencapsulation, 28 ((2)): (142-149). [PMID:21265713] |
| 14. Lindomar A Lerin,Miriam C Feiten,Aline Richetti,Geciane Toniazzo,Helen Treichel,Marcio A Mazutti,J Vladimir Oliveira,Enrique G Oestreicher,Débora de Oliveira. (2011-01-29) Enzymatic synthesis of ascorbyl palmitate in ultrasound-assisted system: process optimization and kinetic evaluation.. Ultrasonics sonochemistry, 18 ((5)): (988-996). [PMID:21273112] |
| 15. Dilyana Paneva,Nevena Manolova,Mariana Argirova,Iliya Rashkov. (2011-07-06) Antibacterial electrospun poly(ɛ-caprolactone)/ascorbyl palmitate nanofibrous materials.. International journal of pharmaceutics, 416 ((1)): (346-355). [PMID:21726615] |
| 16. Luciano Benedini,Maria Laura Fanani,Bruno Maggio,Natalia Wilke,Paula Messina,Santiago Palma,Pablo Schulz. (2011-07-20) Surface phase behavior and domain topography of ascorbyl palmitate monolayers.. Langmuir : the ACS journal of surfaces and colloids, 27 ((17)): (10914-10919). [PMID:21766856] |
| 17. Rupa R Sawant,Onkar S Vaze,Tao Wang', "Gerard G M D'Souza", 'Karen Rockwell,Keyur Gada,Ban-An Khaw,Vladimir P Torchilin. (2011-08-17) Palmitoyl ascorbate liposomes and free ascorbic acid: comparison of anticancer therapeutic effects upon parenteral administration.. Pharmaceutical research, 29 ((2)): (375-383). [PMID:21845505] |
| 18. DeMarquis O Loyd,Sean M Lynch. (2011-08-30) Lipid-soluble vitamin C palmitate and protection of human high-density lipoprotein from hypochlorite-mediated oxidation.. International journal of cardiology, 152 ((2)): (256-257). [PMID:21872949] |
| 19. Bente M Jensen,John Sørensen,Grith Mortensen,Martin B Sørensen,Trine K Dalsgaard. (2011-11-11) Effect of antioxidants on oxidation during the production of whey fat concentrate.. Journal of agricultural and food chemistry, 59 ((24)): (13012-13017). [PMID:22070410] |
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| 22. Mi Kyung Kim,Ji-Soo Lee,Kwang Yup Kim,Hyeon Gyu Lee. (2012-12-19) Ascorbyl palmitate-loaded chitosan nanoparticles: characteristic and polyphenol oxidase inhibitory activity.. Colloids and surfaces. B, Biointerfaces, 103 (391-394). [PMID:23247266] |
| 23. Mirjam Gosenca,Marija Bešter-Rogač,Mirjana Gašperlin. (2013-05-07) Lecithin based lamellar liquid crystals as a physiologically acceptable dermal delivery system for ascorbyl palmitate.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 50 ((1)): (114-122). [PMID:23643736] |
| 24. Li Xiao,Takeki Tsutsui,Nobuhiko Miwa. (2014-06-06) The lipophilic vitamin C derivative, 6-o-palmitoylascorbate, protects human lymphocytes, preferentially over ascorbate, against X-ray-induced DNA damage, lipid peroxidation, and protein carbonylation.. Molecular and cellular biochemistry, 394 ((1-2)): (247-259). [PMID:24898782] |
| 25. Lingyan Kong,Gregory R Ziegler. (2014-07-20) Molecular encapsulation of ascorbyl palmitate in preformed V-type starch and amylose.. Carbohydrate polymers, 111 (256-263). [PMID:25037350] |
| 26. Marija Stojanović,Milica Carević,Mladen Mihailović,Dušan Veličković,Aleksandra Dimitrijević,Nenad Milosavić,Dejan Bezbradica. (2014-09-17) Influence of fatty acid on lipase-catalyzed synthesis of ascorbyl esters and their free radical scavenging capacity.. Biotechnology and applied biochemistry, 62 ((4)): (458-466). [PMID:25224149] |
| 27. Mostafa Nakach,Jean-René Authelin,Tharwat Tadros,Laurence Galet,Alain Chamayou. (2014-10-04) Engineering of nano-crystalline drug suspensions: employing a physico-chemistry based stabilizer selection methodology or approach.. International journal of pharmaceutics, 476 ((1-2)): (277-288). [PMID:25278040] |
| 28. Atikorn Panya,Waranya Temthawee,Natthaporn Phonsatta,Danai Charoensuk,Pawinee Deetae,Wonnop Visessanguan,Eric A Decker. (2015-08-15) Apolar Radical Initiated Conjugated Autoxidizable Triene (ApoCAT) Assay: Effects of Oxidant Locations on Antioxidant Capacities and Interactions.. Journal of agricultural and food chemistry, 63 ((34)): (7546-7555). [PMID:26273904] |
| 29. Rangrong Yoksan,Jatesuda Jirawutthiwongchai,Kridsada Arpo. (2009-12-17) Encapsulation of ascorbyl palmitate in chitosan nanoparticles by oil-in-water emulsion and ionic gelation processes.. Colloids and surfaces. B, Biointerfaces, 76 ((1)): (292-297). [PMID:20004558] |
| 30. Kunikazu Moribe,Sunao Maruyama,Yutaka Inoue,Toyofumi Suzuki,Toshiro Fukami,Kazuo Tomono,Kenjirou Higashi,Yuichi Tozuka,Keiji Yamamoto. (2009-12-17) Ascorbyl dipalmitate/PEG-lipid nanoparticles as a novel carrier for hydrophobic drugs.. International journal of pharmaceutics, 387 ((1-2)): (236-243). [PMID:20005934] |
| 31. Mirjam Gosenca,Aleš Obreza,Slavko Pečar,Mirjana Gašperlin. (2010-09-17) A new approach for increasing ascorbyl palmitate stability by addition of non-irritant co-antioxidant.. AAPS PharmSciTech, 11 ((3)): (1485-1492). [PMID:20845090] |
| 32. Luciano Benedini,Paula V Messina,Santiago D Palma,Daniel A Allemandi,Pablo C Schulz. (2011-10-15) The ascorbyl palmitate-polyethyleneglycol 400-water system phase behavior.. Colloids and surfaces. B, Biointerfaces, 89 (265-270). [PMID:21996464] |
| 33. Feng-Jen Tsai,Yuan-Dai Wang,Cheng-Chi Chen,Chen Hsieh,Zhi-Jiao Cheng,Yu-Jen Wu. (2012-04-28) Evaluation of the antioxidative capability of commonly used antioxidants in dermocosmetics by in vivo detection of protein carbonylation in human stratum corneum.. Journal of photochemistry and photobiology. B, Biology, 112 (7-15). [PMID:22537778] |
| 34. Milagro Mottola,Natalia Wilke,Luciano Benedini,Rafael Gustavo Oliveira,Maria Laura Fanani. (2013-06-29) Ascorbyl palmitate interaction with phospholipid monolayers: electrostatic and rheological preponderancy.. Biochimica et biophysica acta, 1828 ((11)): (2496-2505). [PMID:23806650] |
| 35. Alex C M Oliveira,Matthew R Miller. (2014-05-27) Purification of Alaskan walleye pollock (Gadus chalcogrammus) and New Zealand hoki (Macruronus novaezelandiae) liver oil using short path distillation.. Nutrients, 6 ((5)): (2059-2076). [PMID:24858408] |
| 36. Sukyeong Kim,Sangbin Han,Yeongjae Kim,Hyeon-Seop Kim,Young-Ran Gu,Donghyun Kang,Yongsik Cho,Hyeonkyeong Kim,Jeeyeon Lee,Yeyoung Seo,Moon Jong Chang,Chong Bum Chang,Seung-Baik Kang,Jin-Hong Kim. (2019-10-28) Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation.. Nature communications, 10 ((1)): (4898-4898). [PMID:31653858] |
| 37. Ziwei Wang, Fujun Liu, Ying Luo, Xiangbo Zeng, Xuechen Pei, Guanhua Zhao, Min Zhang, Dayong Zhou, Fawen Yin. (2022) Effects of Tea Polyphenol and Its Combination with Other Antioxidants Added during the Extraction Process on Oxidative Stability of Antarctic Krill (Euphausia superba) Oil. Foods, 11 (23): (3768). [PMID:36496576] [10.3390/foods11233768] |
| 38. Yuling Li, Xiaotong Wu, Zixuan Wu, Mingmin Zhong, Xiaoping Su, Youai Ye, Yan Liu, Lei Tan, Yong Liang. (2022) Colorimetric sensor array based on CoOOH nanoflakes for rapid discrimination of antioxidants in food. Analytical Methods, 14 (28): (2754-2760). [PMID:35781305] [10.1039/D2AY00692H] |
| 39. Sun Dongdong, Wang Zekun, Zhang Pu, Yin Chenyang, Wang Jingyuan, Sun Yu, Chen Ying, Wang Weiyun, Sun Baoliang, Fan Cundong. (2021) Ruthenium-loaded mesoporous silica as tumor microenvironment-response nano-fenton reactors for precise cancer therapy. JOURNAL OF NANOBIOTECHNOLOGY, 19 (1): (1-16). [PMID:33827604] [10.1186/s12951-021-00848-x] |
| 40. Shujie Wang, Guoqin Liu, Weiwei Cheng. (2021) Comparative evaluation of four free radical scavengers for the inhibition of individual glycidyl ester formation in rice bran oil determined by UPLC-MS/MS. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 56 (6): (2983-2991). [PMID:] [10.1111/ijfs.14941] |
| 41. Junhua Li, Yimei Shen, Jiali Zhai, Yujie Su, Luping Gu, Cuihua Chang, Yanjun Yang. (2021) Enhancing the oxidative stability of algal oil powders stabilized by egg yolk granules/lecithin composites. FOOD CHEMISTRY, 345 (128782). [PMID:33302099] [10.1016/j.foodchem.2020.128782] |
| 42. Chang Li,Hanbing Jia,Mingyue Shen,Yuting Wang,Shaoping Nie,Yi Chen,Yongqiang Zhou,Yuanxing Wang,Mingyong Xie. (2015-10-20) Antioxidants Inhibit Formation of 3-Monochloropropane-1,2-diol Esters in Model Reactions.. Journal of agricultural and food chemistry, 63 ((44)): (9850-9854). [PMID:26478126] |
