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INCB3344 - ≥99%, high purity , CAS No.1262238-11-8, Antagonist of CCR2
Basic Description
Synonyms | IDI1_001120 | MZEOSVPWMSEFPW-XYCDVDSTSA-N | CS-0347 | rel-N-[2-[[(3R,4R)-1-[cis-4-(1,3-Benzodioxol-5-yl)-4-hydroxycyclohexyl]-4-ethoxy-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide | INCB 3344 | INCB-3344 | N-(2-(((3R,4R)-1-(trans-4-(Benz |
Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms |
INCB3344 is a potent and selective small molecule CCR2 chemokine receptor antagonist. INCB3344 is useful for anti chronic inflammatory diseases |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ANTAGONIST |
Mechanism of action | Antagonist of CCR2 |
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Names and Identifiers
IUPAC Name | N-[2-[[(3S,4S)-1-[4-(1,3-benzodioxol-5-yl)-4-hydroxycyclohexyl]-4-ethoxypyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide |
INCHI | InChI=1S/C29H34F3N3O6/c1-2-39-25-16-35(21-8-10-28(38,11-9-21)19-6-7-23-24(13-19)41-17-40-23)15-22(25)34-26(36)14-33-27(37)18-4-3-5-20(12-18)29(30,31)32/h3-7,12-13,21-22,25,38H,2,8-11,14-17H2,1H3,(H,33,37)(H,34,36)/t21?,22-,25-,28?/m0/s1 |
InChi Key | MZEOSVPWMSEFPW-XYCDVDSTSA-N |
Canonical SMILES | CCOC1CN(CC1NC(=O)CNC(=O)C2=CC(=CC=C2)C(F)(F)F)C3CCC(CC3)(C4=CC5=C(C=C4)OCO5)O |
Isomeric SMILES | CCO[C@H]1CN(C[C@@H]1NC(=O)CNC(=O)C2=CC(=CC=C2)C(F)(F)F)C3CCC(CC3)(C4=CC5=C(C=C4)OCO5)O |
Alternate CAS | 709018-37-1 |
Molecular Weight | 577.59 |
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