Gemcitabine hydrochloride - 98%, high purity , DNA polymerase (alpha/delta/epsilon) inhibitor, CAS No.122111-03-9, DNA polymerase (alpha/delta/epsilon) inhibitor
Gemcitabine hydrochloride - 98%, high purity , DNA polymerase (alpha/delta/epsilon) inhibitor, CAS No.122111-03-9, DNA polymerase (alpha/delta/epsilon) inhibitor
Gemcitabine hydrochloride is used for treatment of non-small cell lung cancer, pancreatic cancer, mammary cancer, ovarian cancer, bladder cancer, nasopharyngeal carcinoma and non-Hodgkin's lymphoma.Deoxycytidine analog that inhibits DNA synthesis. Metabol
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Action Type
INHIBITOR
Mechanism of action
DNA polymerase (alpha/delta/epsilon) inhibitor
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis.This product is only used for scientific research.
1.Zhimei Wang, Yuehuan Zhang, Qing Chen, Xin Xiao, Carl Redshaw. (2023) Preparation of pelargonic acid vesicles and sustained drug release. Canadian Journal of Chemistry, 101 (2):[PMID:][10.1139/cjc-2022-0075]
2.Yadong Tang,Boxin Huang,Yuqin Dong,Wenlong Wang,Xi Zheng,Wei Zhou,Kun Zhang,Zhiyun Du. (2017-06-07) Three-dimensional prostate tumor model based on a hyaluronic acid-alginate hydrogel for evaluation of anti-cancer drug efficacy.. Journal of biomaterials science. Polymer edition, 28 ((14)):(1603-1616). [PMID:28583017]
References
1.Zhimei Wang, Yuehuan Zhang, Qing Chen, Xin Xiao, Carl Redshaw. (2023) Preparation of pelargonic acid vesicles and sustained drug release. Canadian Journal of Chemistry, 101 (2):[PMID:][10.1139/cjc-2022-0075]
2.Yadong Tang,Boxin Huang,Yuqin Dong,Wenlong Wang,Xi Zheng,Wei Zhou,Kun Zhang,Zhiyun Du. (2017-06-07) Three-dimensional prostate tumor model based on a hyaluronic acid-alginate hydrogel for evaluation of anti-cancer drug efficacy.. Journal of biomaterials science. Polymer edition, 28 ((14)):(1603-1616). [PMID:28583017]
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