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Ellipticine - 97%, high purity , CAS No.519-23-3
Antitumor and intercalating agent; inhibits DNA topoisomerase II
Basic Description Synonyms WLN: T D6 B656 FN LMJ C1 J1 | ICIG 770 | NCGC00015411-09 | CS-5294 | ellipticine | 117VLW7484 | NCGC00015411-10 | UNII-117VLW7484 | BRD-K85985071-001-22-3 | E 3380 | Opera_ID_1748 | Prestwick1_000614 | NCGC00015411-04 | Neuro_000031 | BPBio1_000604 | DTXS Specifications & Purity ≥97% Biochemical and Physiological Mechanisms Naturally occurring plant alkaloid with antitumor activity. DNA intercalating agent; blocks DNA topoisomerase II activity. Prevents p53 phosphorylation in lung cancer cells. Storage Temp Protected from light,Store at -20°C Shipped In Ice chest + Ice pads
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 5,11-dimethyl-6H-pyrido[4,3-b]carbazole INCHI InChI=1S/C17H14N2/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17/h3-9,19H,1-2H3 InChi Key CTSPAMFJBXKSOY-UHFFFAOYSA-N Canonical SMILES CC1=C2C=CN=CC2=C(C3=C1NC4=CC=CC=C43)C Isomeric SMILES CC1=C2C=CN=CC2=C(C3=C1NC4=CC=CC=C43)C Alternate CAS 5081-48-1 PubChem CID 3213 Molecular Weight 246.31
Certificates(CoA,COO,BSE/TSE and Analysis Chart) Safety and Hazards(GHS) Pictogram(s) GHS06 Signal Danger Hazard Statements H301: Toxic if swallowed
Precautionary Statements P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
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