Amifostine thiol - ≥95.0%, high purity , CAS No.31098-42-7

  • ≥96%
Item Number
A646487
Grouped product items
SKUSizeAvailabilityPrice Qty
A646487-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$55.90
A646487-10mg
10mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$85.90
A646487-25mg
25mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$127.90
A646487-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$215.90
A646487-100mg
100mg
Available within 8-12 weeks(?)
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$365.90
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Apoptosis (0) MDM-2/p53 (0)

Basic Description

SynonymsCHEBI:72583 | HY-137864 | AKOS006273087 | Q27104998 | WR1065 | WR-1065 | N-benzyl-N,N-dimethyl-2-(2-(4-(2,4,4-trimethylpentan-2-yl)phenoxy)ethoxy)ethan-1-aminium chloride | NCI60_016501 | N-(2-mercaptoethyl)-1,3-diaminopropane
Specifications & Purity≥96%
Biochemical and Physiological MechanismsAmifostine thiol (WR-1065) is an active metabolite of the cytoprotector Amifostine ( HY-B0639 ). Amifostine thiol is a cytoprotective agent with radioprotective abilities. Amifostine thiol activates p53 through a JNK-dependent signaling pathway[3
Storage TempStore at 2-8°C,Protected from light,Argon charged
Shipped InWet ice
Product Description

Amifostine thiol (WR-1065) is an active metabolite of the cytoprotector Amifostine (HY-B0639). Amifostine thiol is a cytoprotective agent with radioprotective abilities. Amifostine thiol activates p53 through a JNK-dependent signaling pathway .

AI Insight

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-(3-aminopropylamino)ethanethiol
INCHI InChI=1S/C5H14N2S/c6-2-1-3-7-4-5-8/h7-8H,1-6H2
InChi Key YHPLKWQJMAYFCN-UHFFFAOYSA-N
Canonical SMILES C(CN)CNCCS
Isomeric SMILES C(CN)CNCCS
PubChem CID 104807
Molecular Weight 134.24

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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