WR-1065 dihydrochloride - 95%, high purity , CAS No.14653-77-1

Item Number

A134805

Grouped product items
SKU	Size	Availability	Price
A134805-1mg	1mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$12.90
A134805-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$53.90
A134805-10mg	10mg	2	$88.90
A134805-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$200.90
A134805-50mg	50mg	1	$360.90
A134805-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$648.90

p53 activator. Also ROS scavenger

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Basic Description

Synonyms	Amifostine Thiol Dihydrochloride \| Ethanethiol, 2-[(3-aminopropyl)amino]-, hydrochloride (1:2) \| W12622 \| WR-1065 dihydrochloride \| AS-70801 \| AKOS024457577 \| UNII-LE9VV16SZW \| WR 1065 dihydrochloride \| Amifostine thiol, United States Pharmacopeia (USP) R
Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Cell-permeable reactive oxygen species scavenger that activates p53 through a JNK-dependent signaling pathway. Activates p21waf-1and MDM2, represses transcription of Myc and thymidine kinase, and inhibits DNA topoisomerase IIα. Induces cell cycle arrest a
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	Amifostine Thiol Dihydrochloride is a metabolite of Amifostine. A metabolite of Amifostine

Names and Identifiers

Pubchem Sid	504757296
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504757296
IUPAC Name	2-(3-aminopropylamino)ethanethiol;dihydrochloride
INCHI	InChI=1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H
InChi Key	XDRLRDHLCIFZIW-UHFFFAOYSA-N
Canonical SMILES	C(CN)CNCCS.Cl.Cl
Isomeric SMILES	C(CN)CNCCS.Cl.Cl
WGK Germany	3
PubChem CID	146169
Molecular Weight	207.16

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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8 results found

Lot Number	Certificate Type	Date	Item
K2322277	Certificate of Analysis	Nov 09, 2023	A134805
K2322288	Certificate of Analysis	Nov 09, 2023	A134805
K2322289	Certificate of Analysis	Nov 09, 2023	A134805
K2322290	Certificate of Analysis	Nov 09, 2023	A134805
K2322291	Certificate of Analysis	Nov 09, 2023	A134805
K2322292	Certificate of Analysis	Nov 09, 2023	A134805
K2322294	Certificate of Analysis	Nov 09, 2023	A134805
K2322295	Certificate of Analysis	Nov 09, 2023	A134805

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H302:Harmful if swallowed H318:Causes serious eye damage
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help.
WGK Germany	3

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Basic Description