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Zolmitriptan - ≥98%(HPLC), high purity , Serotonin 1d (5-HT1d) receptor agonist, CAS No.139264-17-8, Serotonin 1d (5-HT1d) receptor agonist

1 Citations
Item Number
Z129649
Grouped product items
SKUSizeAvailabilityPrice Qty
Z129649-200mg
200mg
3
$76.90
Z129649-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$86.90
Z129649-1g
1g
3
$269.90
Z129649-5g
5g
3
$1,214.90
Z129649-25g
25g
2
$5,463.90
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Potent 5-HT1B/1D/1Fagonist

View related series
5-HT1A receptor Agonist (0) 5-HT1B receptor Agonist (0) 5-HT1D receptor Agonist (0) 5-ht1e receptor Agonist (0) 5-HT1F receptor Agonist (0)

Basic Description

SynonymsNSC-760383 | ZOLMITRIPTAN (EP MONOGRAPH) | Zomigon | AscoTopand | DB00315 | Tox21_111455 | ZOLMITRIPTAN [WHO-DD] | Zomig ZMT | (4S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone | J-007257 | NC00382 | NCGC00263884-02 | Zolmiptriptan
Specifications & PurityMoligand™, ≥98%(HPLC)
Biochemical and Physiological MechanismsPotent 5-HT1B/1D/1Fagonist (Kivalues are 0.63, 5.01 and 63.09 nM for h5-HT1D, h5-HT1Band h5-HT1Freceptors respectively). Inhibits trigeminal nerve stimulation-mediated neurogenic plasma protein extravasation in guinea pigs; blocks long excitatory postsyna
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeAGONIST
Mechanism of actionSerotonin 1d (5-HT1d) receptor agonist
Product Description

Zolmitriptan is a selective serotonin receptor agonist.
A serotonin 5HTID-receptor agonist.

AI Insight

Product Properties

ALogP2.2

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid504753723
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504753723
IUPAC Name (4S)-4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
INCHI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
InChi Key ULSDMUVEXKOYBU-ZDUSSCGKSA-N
Canonical SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CC3COC(=O)N3
Isomeric SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
WGK Germany 3
RTECS RQ2707000
PubChem CID 60857
Molecular Weight 287.36

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
G2207411Certificate of AnalysisApr 07, 2024 Z129649
G2207412Certificate of AnalysisApr 07, 2024 Z129649
G2207414Certificate of AnalysisApr 07, 2024 Z129649
B2210166Certificate of AnalysisNov 16, 2023 Z129649
L1713088Certificate of AnalysisMay 11, 2023 Z129649

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

H371:May cause damage to organs

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P308+P316:IF exposed or concerned: Get emergency medical help immediately.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS RQ2707000
Merck Index 10189

Related Documents

 SDS

 Specification Sheet

Reviews

Customer Reviews

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Xiaohui Zhang, Yule Wang, Kai Zhang, Hongda Sheng, Yuhan Wu, Huimin Wu, Yingchao Wang, Jianli Guan, Qingfen Meng, Huahuan Li, Zhenhao Li, Guanwei Fan, Yi Wang.  (2021)  Discovery of tetrahydropalmatine and protopine regulate the expression of dopamine receptor D2 to alleviate migraine from Yuanhu Zhitong formula.  PHYTOMEDICINE,  91  (153702).  [PMID:34419734] [10.1016/j.phymed.2021.153702]

References

1. Xiaohui Zhang, Yule Wang, Kai Zhang, Hongda Sheng, Yuhan Wu, Huimin Wu, Yingchao Wang, Jianli Guan, Qingfen Meng, Huahuan Li, Zhenhao Li, Guanwei Fan, Yi Wang.  (2021)  Discovery of tetrahydropalmatine and protopine regulate the expression of dopamine receptor D2 to alleviate migraine from Yuanhu Zhitong formula.  PHYTOMEDICINE,  91  (153702).  [PMID:34419734] [10.1016/j.phymed.2021.153702]

Solution Calculators

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