| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| X753399-GMP-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,220.90 |
XAV 939 synthesized to cGMP guidelines
| Specifications & Purity | GMP, ≥99% |
|---|---|
| Storage Temp | Room temperature |
| Shipped In | Normal |
| Grade | GMP |
| Product Description | Tankyrase Inhibitor; inhibits WNT signaling. Promotes cardiomyocyte differentiation from ESCs |
| IUPAC Name | 2-[4-(trifluoromethyl)phenyl]-3,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one |
|---|---|
| INCHI | InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) |
| InChi Key | KLGQSVMIPOVQAX-UHFFFAOYSA-N |
| Canonical SMILES | C1CSCC2=C1N=C(NC2=O)C3=CC=C(C=C3)C(F)(F)F |
| Isomeric SMILES | C1CSCC2=C1N=C(NC2=O)C3=CC=C(C=C3)C(F)(F)F |
| WGK Germany | 3 |
| PubChem CID | 135418940 |
| Molecular Weight | 312.31 |
| Pictogram(s) | GHS06, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H319:Causes serious eye irritation H301:Toxic if swallowed |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. |
| WGK Germany | 3 |
| 1. Xin Wang, Shoulin Li, Cheng Zhang, Wenping Xu, Mengqi Wu, Jiagao Cheng, Zhong Li, Liming Tao, Yang Zhang. (2024) Stereoselective toxicity of acetochlor chiral isomers on the nervous system of zebrafish larvae. JOURNAL OF HAZARDOUS MATERIALS, 464 (15): (133016). [PMID:37992503] [10.1016/j.jhazmat.2023.133016] |
| 2. Yuan Xu, Jian He, Jun He. (2022) Cyanidin attenuates the high hydrostatic pressure-induced degradation of cellular matrix of nucleus pulposus cell via blocking the Wnt/β-catenin signaling. TISSUE & CELL, 76 (101798). [PMID:35472676] [10.1016/j.tice.2022.101798] |
| 3. Chen Gang, Chen Weicheng, Ye Ming, Tan Weiqiang, Jia Bing. (2019) TRIM59 knockdown inhibits cell proliferation by down-regulating the Wnt/β-catenin signaling pathway in neuroblastoma. BIOSCIENCE REPORTS, 39 (1): [PMID:30389710] [10.1042/BSR20181277] |
| 1. Xin Wang, Shoulin Li, Cheng Zhang, Wenping Xu, Mengqi Wu, Jiagao Cheng, Zhong Li, Liming Tao, Yang Zhang. (2024) Stereoselective toxicity of acetochlor chiral isomers on the nervous system of zebrafish larvae. JOURNAL OF HAZARDOUS MATERIALS, 464 (15): (133016). [PMID:37992503] [10.1016/j.jhazmat.2023.133016] |
| 2. Yuan Xu, Jian He, Jun He. (2022) Cyanidin attenuates the high hydrostatic pressure-induced degradation of cellular matrix of nucleus pulposus cell via blocking the Wnt/β-catenin signaling. TISSUE & CELL, 76 (101798). [PMID:35472676] [10.1016/j.tice.2022.101798] |
| 3. Chen Gang, Chen Weicheng, Ye Ming, Tan Weiqiang, Jia Bing. (2019) TRIM59 knockdown inhibits cell proliferation by down-regulating the Wnt/β-catenin signaling pathway in neuroblastoma. BIOSCIENCE REPORTS, 39 (1): [PMID:30389710] [10.1042/BSR20181277] |
