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Vitamin B₁₂ - for cell and insect cell culture, high purity , CAS No.68-19-9

60 Citations
Item Number
V104142
Grouped product items
SKUSizeAvailabilityPrice Qty
V104142-250mg
250mg
3
$59.90
V104142-1g
1g
3
$141.90
V104142-5g
5g
3
$494.90
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Endogenous Metabolite (957) Metabolic Enzyme/Protease (4858)

Basic Description

SynonymsVB12 | CCG-220433 | Q55167869 | vitamin B12 | CAS-68-19-9 | HMS3713G08 | Cyanocob(III)alamin | HMS1569G08 | Cyanocobalamin;Cyanocob(III)alamin | NCGC00016302-01 | Cobinamide,dihydrogenphosphate(ester),inner salt,3'-ester with(5,6-Dimethyl-1-a-d-ribofurano
Specifications & Purityfor cell culture, for insect cell culture
Storage TempStore at 2-8°C
Shipped InWet ice
Gradefor cell culture, for insect cell culture
Product Description

Vitamin B12 (Cyanocobalamin) is part of a coenzyme needed for the synthesis of proteins and nucleic acids, and for the metabolism of carbohydrates. Vitamin B12 plays a role in the synthesis of myelin. The compound is also used as an antipernicious anemia factor.
A coenzyme for synthesis of nucleic acids and metabolism carbohydrates.

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Names and Identifiers

IUPAC Name cobalt(3+);[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R)-1-[3-[(1R,2R,3R,5Z,7S,10Z,12S,13S,15Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-24-id-3-yl]propanoylamino]propan-2-yl] phosphate;cyanide
INCHI InChI=1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;-1;+3/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;/m1../s1
InChi Key FDJOLVPMNUYSCM-WZHZPDAFSA-L
Canonical SMILES CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=C(C7=NC(=CC8=NC(=C(C4=N5)C)C(C8(C)C)CCC(=O)N)C(C7(C)CC(=O)N)CCC(=O)N)C)[N-]6)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+3]
Isomeric SMILES CC1=CC2=C(C=C1C)N(C=N2)[C@@H]3[C@@H]([C@@H]([C@H](O3)CO)OP(=O)([O-])O[C@H](C)CNC(=O)CC[C@@]4([C@H]([C@@H]5[C@]6([C@@]([C@@H](/C(=C(/C7=N/C(=C\C8=N/C(=C(\C4=N5)/C)/[C@H](C8(C)C)CCC(=O)N)/[C@H]([C@]7(C)CC(=O)N)CCC(=O)N)\C)/[N-]6)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+3]
WGK Germany 1
RTECS GG3750000
PubChem CID 5311498
Molecular Weight 1355.37
Beilstein 4122889

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot NumberCertificate TypeDateItem
D2517055Certificate of AnalysisApr 22, 2025 V104142
K2222391Certificate of AnalysisJul 26, 2024 V104142
H2305273Certificate of AnalysisAug 10, 2023 V104142
H2305276Certificate of AnalysisAug 10, 2023 V104142
H2305281Certificate of AnalysisAug 10, 2023 V104142
H2305287Certificate of AnalysisAug 10, 2023 V104142
H2305291Certificate of AnalysisAug 10, 2023 V104142
C2310595Certificate of AnalysisMar 23, 2023 V104142
C2310596Certificate of AnalysisMar 23, 2023 V104142
C2310594Certificate of AnalysisMar 20, 2023 V104142
H2229168Certificate of AnalysisSep 01, 2022 V104142
H2229169Certificate of AnalysisSep 01, 2022 V104142
H2229170Certificate of AnalysisSep 01, 2022 V104142

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Safety and Hazards(GHS)

WGK Germany 1
RTECS GG3750000
Merck Index 10014

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FAQs and Articles

FAQ
Guidelines For Common Cell Culture Media
Categories: Technical articles
Tags:
Biological buffer Cell medium raw materials Cell culture additives Amino acids Vitamins Growth factors Salt Glucose Nucleosides & nucleotides Carbs Cell culture and transfection

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Citations of This Product

How to Cite Aladdin Scientific Products?
1. Lijia Li, Yiting Gao, Tian Gao, Mengjie Geng, Yue Liu, Fei Teng, Yang Li.  (2024)  Fabrication of water-in-oil-in-gel emulsion gel based on pH-shifting soybean lipophilic protein and carboxymethyl chitosan: Gel performance, physicochemical properties and digestive characteristics.  FOOD HYDROCOLLOIDS,  147  (109385).  [PMID:19484223] [10.1016/j.foodhyd.2023.109385]
2. Qing Fang, Qin Liu, Zongli Xie, Matthew R. Hill, Kaisong Zhang.  (2024)  Ultra-thin PTMSP nanocomposite membranes incorporated with functionalized MoS2 nanosheets for pharmaceutical concentration and solvent recovery.  SEPARATION AND PURIFICATION TECHNOLOGY,  330  (125296).  [PMID:16479015] [10.1016/j.seppur.2023.125296]
3. Qing Li, Xinke Yu, Shiqi Zhang, Mengyue Xu, Yunyi Yang, Zhili Wan, Xiaoquan Yang.  (2023)  All-Natural, Robust, and pH-Responsive Glycyrrhizic Acid-Based Double Network Hydrogels for Controlled Nutrient Release.  ACS Applied Materials & Interfaces,  15  (37): (43633–43647).  [PMID:37695942] [10.1021/acsami.3c10407]
4. Fuge Niu, Mengdi Zhao, Weiwei Tu, Zhe Li, Yi Gao, Yixuan Du, Weichun Pan.  (2023)  Fabrication and stability of W/O/W emulsions stabilized by gum arabic and polyglycerol polyricinoleate.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  104  (2): (797-808).  [PMID:37683081] [10.1002/jsfa.12972]
5. Hukang Guo, Jianxiao Jiang, Chuanjie Fang, Liping Zhu.  (2023)  Highly crystalline and robust covalent organic framework membranes for predictable solvent transport and molecular separation.  Journal of Materials Chemistry A,  11  (36): (19374-19383).  [PMID:] [10.1039/D3TA04108E]
6. Zhankai Zhang, Pei Shan, Zhi-Hong Zhang, Ronghai He, Limin Xing, Jianbin Liu, Degui He, Haile Ma, Zejian Wang, Xianli Gao.  (2023)  Efficient degradation of soybean protein B3 subunit in soy sauce by ultrasound-assisted prolyl endopeptidase and its primary mechanism.  FOOD CHEMISTRY,  429  (136972).  [PMID:37506662] [10.1016/j.foodchem.2023.136972]
7. Luo Gu, Qiuyu Zhu, Xiaoyu Zou, Ru Song.  (2023)  Antibacterial Effect of Shrimp By-Products Hydrolysate on Specific Spoilage Organisms of Squid.  MOLECULES,  28  (10): (4105).  [PMID:37241846] [10.3390/molecules28104105]
8. Xiao Yu, Yanan Chen, Zhiguo Qi, Quan Chen, Yujin Cao, Qingshan Kong.  (2023)  Preparation and identification of a novel peptide with high antioxidant activity from corn gluten meal.  FOOD CHEMISTRY,  424  (136389).  [PMID:37209437] [10.1016/j.foodchem.2023.136389]
9. Qunhuan Ma, Li Zhang.  (2023)  The influences of dissolved inorganic and organic phosphorus on arsenate toxicity in marine diatom Skeletonema costatum and dinoflagellate Amphidinium carterae.  JOURNAL OF HAZARDOUS MATERIALS,  453  (131432).  [PMID:37080037] [10.1016/j.jhazmat.2023.131432]
10. Xiaoyan Ma, Sinong Huang, Yuhong Jin, Hang Jiang, Liangjie Tang, Yifei Wu, Yongjiong Ni, Shijun Zhu, Xueyan Li, Andrea M. Dietrich.  (2023)  Electrocatalytic dechlorination of aqueous trichloroacetic acid by Vitamin B12 modified iron electrode.  Journal of Environmental Chemical Engineering,  11  (109944).  [PMID:] [10.1016/j.jece.2023.109944]
11. Jing Wu, Yong Liu, Lijun Peng, Qisijing Liu, Dawei Wang, Xu Jing, Yaozhong Hu, Jing Lin, Hanyue Fu, Xuemeng Ji, Jingmin Liu, Huan Lv, Bo Peng, Bowei Zhang, Liqiong Guo, Shuo Wang.  (2023)  A Plasmonic Fluor-Lightened Microneedle Array Enables Ultrasensitive Multitarget Whole Blood Diagnosis of Anemia in A Paper Origami-Based Device.  Small,  19  (26): (2300464).  [PMID:36950741] [10.1002/smll.202300464]
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17. Qunhuan Ma, Lizhao Chen, Li Zhang.  (2023)  Effects of phosphate on the toxicity and bioaccumulation of arsenate in marine diatom Skeletonema costatum.  SCIENCE OF THE TOTAL ENVIRONMENT,  857  (159566).  [PMID:36265640] [10.1016/j.scitotenv.2022.159566]
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27. Xiang Yingying, Song Fei, Jiang Lei, Liu Ze, Tu Yujiao.  (2022)  Novel Fluorescent Nano Carbon Quantum Dots Derived From Lactarius Hatsudake for High Selective Vitamin B12 Detection.  JOURNAL OF AOAC INTERNATIONAL,  105  (5): (1350-1359).  [PMID:35244160] [10.1093/jaoacint/qsac033]
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38. Yujiao Tu, Suping Wang, Xiaotian Yuan, Pengfei Song, Yunlin Wei, Kunhao Qin, Qi Zhang, Xiuling Ji.  (2020)  Hydrothermal synthesis of Auricularia auricula derived nitrogen, phosphorus-doped carbon dots and application in Ag(I) and 4-nitrophenol detection and bioimaging.  Analytical Methods,  12  (17): (2237-2243).  [PMID:] [10.1039/D0AY00316F]
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43. Xianli Gao, Ermeng Liu, Junke Zhang, Mingquan Yang, Sui Chen, Zhan Liu, Haile Ma, Feng Hu.  (2019)  Effects of sonication during moromi fermentation on antioxidant activities of compounds in raw soy sauce.  LWT-FOOD SCIENCE AND TECHNOLOGY,  116  (108605).  [PMID:] [10.1016/j.lwt.2019.108605]
44. Jukai Zhou, Shuqing Zhang, Xin Song, Ran Wei, Xiang Zhang, Weifeng Zhao, Changsheng Zhao.  (2019)  Three-Dimensional Graphene Oxide Skeleton Guided Poly(acrylic Acid) Composite Hydrogel Particles with Hierarchical Pore Structure for Hemoperfusion.  ACS Biomaterials Science & Engineering,  5  (8): (3987–4001).  [PMID:33443421] [10.1021/acsbiomaterials.9b00712]
45. Xianli Gao, Junke Zhang, Ermeng Liu, Mingquan Yang, Sui Chen, Feng Hu, Haile Ma, Zhan Liu, Xueting Yu.  (2019)  Enhancing the taste of raw soy sauce using low intensity ultrasound treatment during moromi fermentation.  FOOD CHEMISTRY,  298  (124928).  [PMID:31272053] [10.1016/j.foodchem.2019.05.202]
46. Yao Long, Li Zhang, Ying Yu, Bixia Lin, Yujuan Cao, Manli Guo.  (2019)  Silicon nanoparticles synthesized using a microwave method and used as a label-free fluorescent probe for detection of VB12.  LUMINESCENCE,  34  (6): (544-552).  [PMID:31119853] [10.1002/bio.3651]
47. Chun-Er Lin, Li-Feng Fang, Shi-Yuan Du, Zhi-Kan Yao, Bao-Ku Zhu.  (2019)  A novel positively charged nanofiltration membrane formed via simultaneous cross-linking/quaternization of poly(m-phenylene isophthalamide)/polyethyleneimine blend membrane.  SEPARATION AND PURIFICATION TECHNOLOGY,  212  (101).  [PMID:] [10.1016/j.seppur.2018.11.026]
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49. Li-Feng Fang, Ming-Yong Zhou, Liang Cheng, Bao-Ku Zhu, Hideto Matsuyama, Shuaifei Zhao.  (2019)  Positively charged nanofiltration membrane based on cross-linked polyvinyl chloride copolymer.  JOURNAL OF MEMBRANE SCIENCE,  572  (28).  [PMID:] [10.1016/j.memsci.2018.10.054]
50. Chuanjie Fang, Jian Sun, Bin Zhang, Yuchen Sun, Liping Zhu, Hideto Matsuyama.  (2018)  Preparation of positively charged composite nanofiltration membranes by quaternization crosslinking for precise molecular and ionic separations.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  531  (168).  [PMID:30031259] [10.1016/j.jcis.2018.07.034]
51. Chun-Er Lin, Ming-Yong Zhou, Wei-Song Hung, Bao-Ku Zhu, Kueir-Rarn Lee, Li-Ping Zhu, Li-Feng Fang.  (2018)  Ultrathin nanofilm with tailored pore size fabricated by metal-phenolic network for precise and rapid molecular separation.  SEPARATION AND PURIFICATION TECHNOLOGY,  207  (435).  [PMID:] [10.1016/j.seppur.2018.06.077]
52. Bo Yang, Jianping Deng, Liyan Wei, Yanni Han, Gang Yu, Shubo Deng, Caizhen Zhu, Huabo Duan, Qiongfang Zhuo.  (2018)  Synergistic effect of ball-milled Al micro-scale particles with vitamin B12 on the degradation of 2,2′,4,4′-tetrabromodiphenyl ether in liquid system.  CHEMICAL ENGINEERING JOURNAL,  333  (613).  [PMID:] [10.1016/j.cej.2017.09.183]
53. Chunming Chen, Bingxin Chen, Redong Hong.  (2017)  Preparation and properties of alkaline anion exchange membrane with semi-interpenetrating polymer networks based on poly(vinylidene fluoride-co-hexafluoropropylene).  JOURNAL OF APPLIED POLYMER SCIENCE,  135  (5): (45775).  [PMID:] [10.1002/app.45775]
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