| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| V427227-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 |
| Synonyms | VALPROIC ACID | 2-Propylpentanoic acid | 99-66-1 | 2-Propylvaleric acid | Dipropylacetic acid | Depakene | Depakine | Valproate | Mylproin | Ergenyl | Di-n-propylacetic acid | Propylvaleric acid | Pentanoic acid, 2-propyl- | n-Dipropylacetic acid | 4-Heptanecarboxylic acid | Myproic A |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Anticonvulsant that also has efficacy as a mood stabilizer in bipolar disorder |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Action Type | INHIBITOR |
| Mechanism of action | Inhibitor of histone deacetylase 1 |
| ALogP | 2.8 |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | 2-propylpentanoic acid |
|---|---|
| INCHI | InChI=1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10) |
| InChi Key | NIJJYAXOARWZEE-UHFFFAOYSA-N |
| Canonical SMILES | CCCC(CCC)C(=O)O |
| Isomeric SMILES | CCCC(CCC)C(=O)O |
| PubChem CID | 3121 |
| Molecular Weight | 144.21 |
| Pictogram(s) | GHS08, GHS05, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H318:Causes serious eye damage H360:May damage fertility or the unborn child |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| Merck Index | 9913 |
| 1. Chuanchuan Wang, Weixuan Chen, Yishan Jiang, Xiao Xiao, Qianhui Zou, Jiarui Liang, Yu Zhao, Qianxu Wang, Tian Yuan, Rui Guo, Xuebo Liu, Zhigang Liu. (2024) A synbiotic formulation of Lactobacillus reuteri and inulin alleviates ASD-like behaviors in a mouse model: the mediating role of the gut–brain axis. Food & Function, 15 (1): (387-400). [PMID:38099485] [10.1039/D3FO02663A] |
| 2. Meili Guo, Gang Zhang, Ruoli Zhao, Huizhen Ma, Yuxing Yan, Shuyu Yang, Jian Meng, You Huang, Xiao-Dong Zhang, Hao Wang, Ruiping Zhang. (2023) Ligand Engineering of Gold Nanoclusters for NIR-II Imaging. ACS Applied Nano Materials, 6 (17): (15945–15958). [PMID:] [10.1021/acsanm.3c02888] |
| 3. Peixin Li, Yanfang Sun, Lei Nie, Amin Shavandi, Khaydar E. Yunusov, Yinjian Hua, Guohua Jiang. (2023) Fabrication of carboxymethyl cellulose/hyaluronic acid/polyvinylpyrrolidone composite pastes incorporation of minoxidil-loaded ferulic acid-derived lignin nanoparticles and valproic acid for treatment of androgenetic alopecia. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 249 (126013). [PMID:37517761] [10.1016/j.ijbiomac.2023.126013] |
| 1. Chuanchuan Wang, Weixuan Chen, Yishan Jiang, Xiao Xiao, Qianhui Zou, Jiarui Liang, Yu Zhao, Qianxu Wang, Tian Yuan, Rui Guo, Xuebo Liu, Zhigang Liu. (2024) A synbiotic formulation of Lactobacillus reuteri and inulin alleviates ASD-like behaviors in a mouse model: the mediating role of the gut–brain axis. Food & Function, 15 (1): (387-400). [PMID:38099485] [10.1039/D3FO02663A] |
| 2. Meili Guo, Gang Zhang, Ruoli Zhao, Huizhen Ma, Yuxing Yan, Shuyu Yang, Jian Meng, You Huang, Xiao-Dong Zhang, Hao Wang, Ruiping Zhang. (2023) Ligand Engineering of Gold Nanoclusters for NIR-II Imaging. ACS Applied Nano Materials, 6 (17): (15945–15958). [PMID:] [10.1021/acsanm.3c02888] |
| 3. Peixin Li, Yanfang Sun, Lei Nie, Amin Shavandi, Khaydar E. Yunusov, Yinjian Hua, Guohua Jiang. (2023) Fabrication of carboxymethyl cellulose/hyaluronic acid/polyvinylpyrrolidone composite pastes incorporation of minoxidil-loaded ferulic acid-derived lignin nanoparticles and valproic acid for treatment of androgenetic alopecia. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 249 (126013). [PMID:37517761] [10.1016/j.ijbiomac.2023.126013] |
