≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
C-170 is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research.
In vitro activity:
In THP-1 cells, pretreated with STING-IN-2 (C-170;?0.5 μM) and stimulated with cGAMP.?STING-IN-2 (C-170) treatment decreases the IFNB1 and TNF mRNA levels, and also reduces the p-TBK1 levels
| Pubchem Sid | 488192040 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488192040 |
| Canonical Smiles | CCCCC1=CC=C(C=C1)NC(=O)C2=CC=C(O2)[N+](=O)[O-] |
| IUPAC Name | N-(4-butylphenyl)-5-nitrofuran-2-carboxamide |
| InChIKey | QMVOHFICEFYHMK-UHFFFAOYSA-N |
| INCHI | 1S/C15H16N2O4/c1-2-3-4-11-5-7-12(8-6-11)16-15(18)13-9-10-14(21-13)17(19)20/h5-10H,2-4H2,1H3,(H,16,18) |
| Isomeric SMILES | CCCCC1=CC=C(C=C1)NC(=O)C2=CC=C(O2)[N+](=O)[O-] |
| Molecular Weight | 288.3 |
| Reaxy-Rn | 33322204 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=33322204&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2328256 | Certificate of Analysis | Jan 19, 2026 | C420025 |
| C2328259 | Certificate of Analysis | Jan 19, 2026 | C420025 |
| C2328261 | Certificate of Analysis | Jan 19, 2026 | C420025 |
| C2328262 | Certificate of Analysis | Jan 19, 2026 | C420025 |
| C2328267 | Certificate of Analysis | Jan 19, 2026 | C420025 |
| C2328287 | Certificate of Analysis | Jan 19, 2026 | C420025 |
| C2328288 | Certificate of Analysis | Jan 19, 2026 | C420025 |
| C2328298 | Certificate of Analysis | Jan 19, 2026 | C420025 |
| Solubility | DMSO:10 mM |
|---|---|
| Molecular Weight | 288.300 g/mol |
| XLogP3 | 4.200 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 5 |
| Exact Mass | 288.111 Da |
| Monoisotopic Mass | 288.111 Da |
| Topological Polar Surface Area | 88.100 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 361.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
