PSB CB5 - ≥98%(HPLC) , CAS No.1627710-30-8

CAS: 1627710-30-8 Cat. No.: P288869 Molecular Weight: 384.88 PubChem CID: 85469571
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(HPLC)
Synonyms
PSB CB5 | (Z)-2-(3-((4-Chlorobenzyl)oxy)benzylidene)-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3(2H)-one | Q19903835 | 1627710-30-8 | 5H-Imidazo(2,1-b)(1,3)thiazin-3(2H)-one, 2-((3-((4-chlorophenyl)methoxy)phenyl)methylene)-6,7-dihydro-, (2Z)- | 75Q5Q6F7L
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
P288869-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$426.90
50mg
P288869-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,798.90
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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
PSB CB5 | (Z)-2-(3-((4-Chlorobenzyl)oxy)benzylidene)-6, 7-dihydro-5H-imidazo[2, 1-b][1, 3]thiazin-3(2H)-one | Q19903835 | 1627710-30-8 | 5H-Imidazo(2, 1-b)(1, 3)thiazin-3(2H)-one, 2-((3-((4-chlorophenyl)methoxy)phenyl)methylene)-6, 7-dihydro-, (2Z)- | 75Q5Q6F7L
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Selective GPR18 antagonist (IC50= 0.279 μM). Exhibits >36-fold selectivity versus CB1and GPR55 and 14-fold selectivity versus CB2receptors. InhibitsN-Arachidonylglycine induced acrosomal exocytosis in human spermatozoa.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%(HPLC)
Names and Identifiers
Canonical SmilesC1CN2C(=O)C(=CC3=CC(=CC=C3)OCC4=CC=C(C=C4)Cl)N=C2SC1
IUPAC Name(2Z)-2-[[3-[(4-chlorophenyl)methoxy]phenyl]methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-one
InChIKeyXJBQRMOGMULGPP-PDGQHHTCSA-N
INCHI1S/C20H17ClN2O2S/c21-16-7-5-14(6-8-16)13-25-17-4-1-3-15(11-17)12-18-19(24)23-9-2-10-26-20(23)22-18/h1,3-8,11-12H,2,9-10,13H2/b18-12-
Isomeric SMILES C1CN2C(=O)/C(=C/C3=CC(=CC=C3)OCC4=CC=C(C=C4)Cl)/N=C2SC1
PubChem CID 85469571
Molecular Weight 384.88

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR2 Tchem Cannabinoid CB2 receptor (16942 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GPR55 Tclin G-protein coupled receptor 55 (1594 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GPR35 Tchem G-protein coupled receptor 35 (2643 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySolvent:DMSO, Max Conc. mg/mL: 7.7, Max Conc. mM: 20
Molecular Weight384.900 g/mol
XLogP34.700
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass384.07 Da
Monoisotopic Mass384.07 Da
Topological Polar Surface Area67.200 Ų
Heavy Atom Count26
Formal Charge0
Complexity586.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

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