🌎 Ship to: United States
Toggle Nav
Cart
Buscar
Envío en el mismo día para todos los artículos en stock.
Búsqueda avanzada
Pedido rápido SDS CoA
Menú
Cuenta
Configuración
྾
224,000+ productos de investigación · Triple ISO certified · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items

ZM 306416 - Moligand™, ≥98% , Inhibitor of epidermal growth factor receptor;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of kinase insert domain receptor, CAS No.690206-97-4, Inhibitor of epidermal growth factor receptor;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of kinase insert domain receptor

CAS: 690206-97-4 Cat. No.: Z129748 Peso molecular: 333.74 PubChem CID: 5329006
COA
ZM 306416 - Moligand™, ≥98% CAS No(690206-97-4) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
s2897 | HY-13785 | KBio2_005169 | N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxy-4-quinazolinamine | 1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole | C16H13ClFN3O2 | SB16593 | 4-Quinazolinamine,N-(4-chloro-2-fluorophenyl)-6,7-dimethox
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
10mg
Z129748-10mg
3

71,90US$

107,90US$
Guardar 36,00 US$ (33.36%)
50mg
Z129748-50mg
3

180,90US$

271,90US$
Guardar 91,00 US$ (33.47%)
Enter a quantity for the sizes you want to add.
Bulk / Custom
♡ Lista de deseos ⇅ Añadir para comparar ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Descripción general Specifications Nombres e identificadores Documentation Advanced Data Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Preguntas frecuentes y artículos Calculadoras de soluciones Reseñas
🧪

Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

ZM-306416(CB 676475) is a VEGFR inhibitor that inhibits Flk-1 (KDR) (IC50=100 nM) and Flt (IC50 =2 μM); displays 4-fold selectivity over FGFR-1; inhibitor of c-Abl, Flt-1 and Src

Specifications

Sinónimos
s2897 | HY-13785 | KBio2_005169 | N-(4-Chloro-2-fluorophenyl)-6, 7-dimethoxy-4-quinazolinamine | 1-[2-[(4-Chlorophenyl)methoxy]-2-(2, 4-dichlorophenyl)ethyl]-1H-imidazole | C16H13ClFN3O2 | SB16593 | 4-Quinazolinamine, N-(4-chloro-2-fluorophenyl)-6, 7-dimethox
Especificaciones y pureza
Moligand™, ≥98%
Mecanismos bioquímicos y fisiológicos

Description: IC50 Value: 0.67uM(for VEGFR); 0.33±0.08uM(for Src); 1.3±0.2 μM(for Abl) ZM-306416, a vascular endothelial growth factor receptor (VEGFR) antagonist, was identified as a potent inhibitor of EGFR function [2].

Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Mecanismo de acción
Inhibitor of epidermal growth factor receptor;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of kinase insert domain receptor
Pureza
≥98%
Nombres e identificadores
Sonrisas canónicasCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC
IUPAC NameN-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
InChIKeyYHUIUSRCUKUUQA-UHFFFAOYSA-N
INCHI1S/C16H13ClFN3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18/h3-8H,1-2H3,(H,19,20,21)
Isómeros SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC
PubChem CID 5329006
Peso molecular 333.74

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
EGFR Tclin Epidermal growth factor receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FLT1 Tclin Vascular endothelial growth factor receptor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDR Tclin Vascular endothelial growth factor receptor 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FGFR1 Tclin Fibroblast growth factor receptor 1 (9149 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FLT1 Tclin Vascular endothelial growth factor receptor 1 (6262 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EPHB2 Tchem Ephrin type-B receptor 2 (1899 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FLT1 Tclin Vascular endothelial growth factor receptor (287 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDR Tclin VEGF-receptor 2 and Fibroblast growth factor receptor 1 (50 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
H1816137Certificate of AnalysisNov 06, 2025 Z129748
H1816136Certificate of AnalysisNov 06, 2025 Z129748
E1625071Certificate of AnalysisJul 09, 2025 Z129748
Propiedades químicas y físicas
SolubilidadDMSO:3 mg/mL; ethanol:1 mg/mL, DMSO:3 mg/mL; ethanol:1 mg/mL
Peso molecular333.740 g/mol
XLogP34.100
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass333.068 Da
Monoisotopic Mass333.068 Da
Topological Polar Surface Area56.300 Ų
Heavy Atom Count23
Formal Charge0
Complexity392.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Wnt/β-Catenin Signaling Pathway
Categories: Technical articles
Tags:
Wnt/β-Catenin signaling pathway Cell regulation Wnt protein Stem cell fate Embryonic development Receptor complex Signal modulator
Comprehensive Overview of Vascular Endothelial Gth Factors (VEGF)
Categories: Technical articles
Tags:
Regenerative medicine Vascular endothelial growth factor VEGF PlGF Angiogenesis Lymphogenesis
VEGF Signaling Pathway: Receptor Lineage, Activation Mechanisms, and Biological Effects
Categories: Technical articles
Tags:
VEGF Angiogenesis Endothelial cells PI3K-AKT VEGFR Vascular permeability lymphangiogenesis MAPK
Calculadoras de soluciones
Reseñas

Reseñas de cliente

We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our Cookie Policy.

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.

Privacy Policy Terms of Use Cookie Policy Terms and Conditions of Sale Sales Policy
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.