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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items TH287 - ≥98% , CAS No.1609960-30-6
Synonyms
SCHEMBL15757374 | (S)-N-(6-chloro-5-(2-(5-(2-fluoro-4-methylphenyl)-2-methyl-7,8-dihydro-[1,3,4]thiadiazolo[2?,3?:2,3]imidazo[4,5-c]pyridin-6(5H)-yl)- 2-oxoethoxy)pyridin-2-yl)methanesulfonamide | UNII-R6DCB5MSM2 | TH287 | TH-287 | CCG-267139 | Q27452986
Shipped In
Ice chest + Ice pads
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
SCHEMBL15757374 | (S)-N-(6-chloro-5-(2-(5-(2-fluoro-4-methylphenyl)-2-methyl-7, 8-dihydro-[1, 3, 4]thiadiazolo[2?, 3?:2, 3]imidazo[4, 5-c]pyridin-6(5H)-yl)- 2-oxoethoxy)pyridin-2-yl)methanesulfonamide | UNII-R6DCB5MSM2 | TH287 | TH-287 | CCG-267139 | Q27452986
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
TH287 is a potent inhibitor of human 7, 8-Dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1) with an IC50 value of 0.8 nM. MTH1 hydrolyzes oxidized purine nucleoside triphosphates that might otherwise be incorporated into DNA/RNA and contribute to DNA damage.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nombres e identificadores Pubchem Sid 504772332 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504772332 Sonrisas canónicas CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N IUPAC Name 6-(2,3-dichlorophenyl)-4-N-methylpyrimidine-2,4-diamine InChIKey URWCXPXBBITYLR-UHFFFAOYSA-N INCHI 1S/C11H10Cl2N4/c1-15-9-5-8(16-11(14)17-9)6-3-2-4-7(12)10(6)13/h2-5H,1H3,(H3,14,15,16,17) Isómeros SMILES CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N PubChem CID 73441664 Peso molecular 269.13
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad 5 mg/mL, clear (warmed) Peso molecular 269.130 g/mol XLogP3 3.100 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 2 Exact Mass 268.028 Da Monoisotopic Mass 268.028 Da Topological Polar Surface Area 63.800 Ų Heavy Atom Count 17 Formal Charge 0 Complexity 254.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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