Nω-Hydroxy-nor-L-Arginine Dihydrochloride - Moligand™, ≥97% , CAS No.291758-32-2

CAS: 291758-32-2 Cat. No.: N351768 Peso molecular: 249.1

GRADE & PURITY Moligand™, ≥97%

Synonyms

(2S)-2-Amino-4-(((hydroxyamino)iminomethyl)amino)butanoic acid | (2S)-2-amino-4-[(E)-2-hydroxycarbamimidamido]butanoic acid | N.OMEGA.-HYDROXY-NOR-L-ARGININE | CHEBI:191070 | F0001-2381 | J842.499C | Q27088086 | Butanoic acid,2-amino-4-[[(hydroxyamino)imi

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

Competitive, reversible inhibitor of arginase. Neither a substrate nor an inhibitor for iNOS and useful for studying interplays between arginase and NOS. More potent than NOHA and homo-NOHA.

Specifications

Sinónimos

(2S)-2-Amino-4-(((hydroxyamino)iminomethyl)amino)butanoic acid | (2S)-2-amino-4-[(E)-2-hydroxycarbamimidamido]butanoic acid | N.OMEGA.-HYDROXY-NOR-L-ARGININE | CHEBI:191070 | F0001-2381 | J842.499C | Q27088086 | Butanoic acid, 2-amino-4-[[(hydroxyamino)imi

Especificaciones y pureza

Moligand™, ≥97%

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

INHIBITOR

Pureza

≥97%

Nombres e identificadores

• Sonrisas canónicas: C(CN=C(N)NO)C(C(=O)O)N
• IUPAC Name: (2S)-2-amino-4-[[amino-(hydroxyamino)methylidene]amino]butanoic acid
• InChIKey: KOBHCUDVWOTEKO-VKHMYHEASA-N
• INCHI: 1S/C5H12N4O3/c6-3(4(10)11)1-2-8-5(7)9-12/h3,12H,1-2,6H2,(H,10,11)(H3,7,8,9)/t3-/m0/s1
• Isómeros SMILES: C(CN=C(N)NO)[C@@H](C(=O)O)N
• Peso molecular: 249.1
• Reaxy-Rn: 33050234
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=33050234&ln=

Objetivos asociados (humanos)

ARG2 Tchem Arginase-2, mitochondrial (2 Activities)

Discover Target: ARG2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ARG1 Tchem Arginase-1 (2 Activities)

Discover Target: ARG1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Objetivos asociados (no humanos)

Rattus norvegicus (775804 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ARG1 Arginase-1 (70 Activities)

Discover Target: ARG1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Índice de refracción: n20D~1.62 (Predicted)
• Rotación específica [α]: α24D+14°±2°, c = 1 in 80% acetic acid
• Peso molecular: 176.170 g/mol
• XLogP3: -4.600
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 176.091 Da
• Monoisotopic Mass: 176.091 Da
• Topological Polar Surface Area: 134.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 182.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1