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MRT 10 - ≥98% , CAS No.330829-30-6

CAS: 330829-30-6 Cat. No.: M287792 Peso molecular: 465.52 Número EC: 694-371-1
COA
MRT 10 - ≥98% CAS No(330829-30-6) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
EX-A7242 | J-019016 | MRT-10, >=98% (HPLC) | MS-28575 | 3,4,5-trimethoxy-N-({3-[(phenylcarbonyl)amino]phenyl}carbamothioyl)benzamide | AKOS000619111 | N-((3-Benzamidophenyl)carbamothioyl)-3,4,5-trimethoxybenzamide | n-(3-benzamidophenylcarbamothioyl)-3,4,
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5mg
M287792-5mg
6

109,90US$

164,90US$
Guardar 55,00 US$ (33.35%)
10mg
M287792-10mg
5

196,90US$

295,90US$
Guardar 99,00 US$ (33.46%)
25mg
M287792-25mg
3

429,90US$

644,90US$
Guardar 215,00 US$ (33.34%)
50mg
M287792-50mg
3

730,90US$

1.096,90US$
Guardar 366,00 US$ (33.37%)
100mg
M287792-100mg
3

1.242,90US$

1.864,90US$
Guardar 622,00 US$ (33.35%)
Enter a quantity for the sizes you want to add.
Bulk / Custom
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Descripción general Specifications Nombres e identificadores Documentation Advanced Data Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Product description

MRT-10 is a seven-transmembrane receptor smoothened (Smo) antagonist with an IC50 of 0.65 μM in the micromolar range in various Hedgehog (Hh) assays. MRT-10 binds to the Smo receptor at the level of the Bodipycyclopamine binding site. MRT-10 can be used for the research of cancer.

Specifications

Sinónimos
EX-A7242 | J-019016 | MRT-10, >=98% (HPLC) | MS-28575 | 3, 4, 5-trimethoxy-N-({3-[(phenylcarbonyl)amino]phenyl}carbamothioyl)benzamide | AKOS000619111 | N-((3-Benzamidophenyl)carbamothioyl)-3, 4, 5-trimethoxybenzamide | n-(3-benzamidophenylcarbamothioyl)-3, 4,
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
Smoothened (Smo) receptor antagonist (IC50= 0.5μM in HEK293 cells transiently expressing mouse Smo). Inhibits ShhN-induced Gli luciferase reporter activity in Shh-light 2 cells (IC50= 2.5μM); acts as an inverse agonist during nontranscriptional Hedgehog p
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
ANTAGONIST
Pureza
≥98%
Nombres e identificadores
Pubchem Sid488191726
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488191726
Sonrisas canónicasCOC1=CC(=CC(=C1OC)OC)C(=O)NC(=S)NC2=CC=CC(=C2)NC(=O)C3=CC=CC=C3
IUPAC NameN-[(3-benzamidophenyl)carbamothioyl]-3,4,5-trimethoxybenzamide
InChIKeyKVQVEZQDNHMQJV-UHFFFAOYSA-N
INCHI1S/C24H23N3O5S/c1-30-19-12-16(13-20(31-2)21(19)32-3)23(29)27-24(33)26-18-11-7-10-17(14-18)25-22(28)15-8-5-4-6-9-15/h4-14H,1-3H3,(H,25,28)(H2,26,27,29,33)
Isómeros SMILES COC1=CC(=CC(=C1OC)OC)C(=O)NC(=S)NC2=CC=CC(=C2)NC(=O)C3=CC=CC=C3
Peso molecular 465.52
Reaxy-Rn 21883721
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21883721&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMO Tclin Smoothened homolog (1371 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
C3H 10T1/2 (488 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Shh Sonic hedgehog protein (356 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeFechaArticulo
E2320641Certificate of AnalysisMar 11, 2026 M287792
E2320647Certificate of AnalysisMar 11, 2026 M287792
E2320654Certificate of AnalysisMar 11, 2026 M287792
E2320665Certificate of AnalysisMar 11, 2026 M287792
E2320670Certificate of AnalysisMar 11, 2026 M287792
E2320674Certificate of AnalysisMar 11, 2026 M287792
E2320683Certificate of AnalysisMar 11, 2026 M287792
E2320684Certificate of AnalysisMar 11, 2026 M287792
E2320691Certificate of AnalysisMar 11, 2026 M287792
E2320692Certificate of AnalysisMar 11, 2026 M287792
Propiedades químicas y físicas
SolubilidadSolvent:DMSO, Max Conc. mg/mL: 46.55, Max Conc. mM: 100
Peso molecular465.500 g/mol
XLogP34.300
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass465.136 Da
Monoisotopic Mass465.136 Da
Topological Polar Surface Area130.000 Ų
Heavy Atom Count33
Formal Charge0
Complexity658.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
Reseñas

Reseñas de cliente

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