ML-9 - ≥98%(TLC) , CAS No.105637-50-1

CAS: 105637-50-1 Cat. No.: M165683 Peso molecular: 361.29 PubChem CID: 108047

GRADE & PURITY ≥98%(TLC)

Synonyms

ML-9 hydrochloride | C 1172 | J-001466 | ML-9 | ML-9, >=99% (TLC), powder | NSC 734549 | EX-A4928 | NCGC00260894-01 | NSC734549 | NSC-734549 | Iron(III) chloride, reagent grade, 97% | K00008 | ML-9 HCl | 1-((5-CHLORONAPHTHALEN-1-YL)SULFONYL)-1,4-DIAZEPANE

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Sinónimos

ML-9 hydrochloride | C 1172 | J-001466 | ML-9 | ML-9, >=99% (TLC), powder | NSC 734549 | EX-A4928 | NCGC00260894-01 | NSC734549 | NSC-734549 | Iron(III) chloride, reagent grade, 97% | K00008 | ML-9 HCl | 1-((5-CHLORONAPHTHALEN-1-YL)SULFONYL)-1, 4-DIAZEPANE

Especificaciones y pureza

≥98%(TLC)

Mecanismos bioquímicos y fisiológicos

ML-9 is myosin light chain kinase inhibitor. It inhibits insulin-induced translocation of glucose transporters GLUT4 and GLUT1 in a dose-dependent manner. ML-9 also inhibits agonist-induced Ca2+ entry into endothelial cells and catecholamine secretion in

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%(TLC)

Nombres e identificadores

• Pubchem Sid: 504756648
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504756648
• Sonrisas canónicas: C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3Cl.Cl
• IUPAC Name: 1-(5-chloronaphthalen-1-yl)sulfonyl-1,4-diazepane;hydrochloride
• InChIKey: ZNRYCIVTNLZOGI-UHFFFAOYSA-N
• INCHI: 1S/C15H17ClN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H
• Isómeros SMILES: C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3Cl.Cl
• WGK Alemania: 3
• PubChem CID: 108047
• Peso molecular: 361.29

Objetivos asociados (humanos)

TRPV1 Tclin Vanilloid receptor (8273 Activities)

Discover Target: TRPV1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PRKX Tchem Serine/threonine-protein kinase PRKX (2278 Activities)

Discover Target: PRKX

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Mapk1 MAP kinase ERK2 (650 Activities)

Discover Target: Mapk1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

nfo Endonuclease 4 (425 Activities)

Discover Target: nfo

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Peso molecular: 361.300 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 360.047 Da
• Monoisotopic Mass: 360.047 Da
• Topological Polar Surface Area: 57.800 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 451.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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