≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Lesinurad sodium Lesinurad (Selexipag, RDEA-594) sodium (Zurampic) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout. Lesinurad sodium inhibits the uric acid transporter URAT1 and Kidney transporter OAT with IC50/Km of 4.3 μM/0.85 μM and 3.5 μM/2 μM for OAT1 and OAT3, respectively.
Targets
URAT1 ; OAT1 (Cell-free assay); OAT3 (Cell-free assay); OAT3 (Cell-free assay); OAT1 (Cell-free assay) ; 0.85 μM(Km); 2 μM(Km); 3.5 μM; 4.3 μM
| ALogP | 2.783 |
|---|---|
| hba_count | 2 |
| Enlace rotable | 5 |
| Pubchem Sid | 488201789 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488201789 |
| Sonrisas canónicas | C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)[O-].[Na+] |
| IUPAC Name | sodium;2-[[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-1,2,4-triazol-3-yl]sulfanyl]acetate |
| InChIKey | FVYMVLTWIBGEMC-UHFFFAOYSA-M |
| INCHI | 1S/C17H14BrN3O2S.Na/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14;/h1-4,7-8,10H,5-6,9H2,(H,22,23);/q;+1/p-1 |
| Isómeros SMILES | C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)[O-].[Na+] |
| Peso molecular | 426.26 |
| Reaxy-Rn | 19298555 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19298555&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
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| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 G2304568 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304570 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304571 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304574 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304575 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304609 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304694 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304695 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304696 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304572 | Certificate of Analysis | May 26, 2023 | L413240 |
| Solubilidad | Solubility (25°C) In vitro DMSO: 85 mg/mL (199.4 mM); Ethanol: 85 mg/mL (199.4 mM); Water: 8 mg/mL (18.76 mM); |
|---|---|
| DMSO (mg/ml) Solubilidad máxima | 85 |
| DMSO (mM) Solubilidad máxima | 199.408811523483 |
| Agua (mg/ml) Solubilidad máxima | 8 |
| Agua (mM) Solubilidad máxima | 18.7678881433867 |
| Peso molecular | 426.300 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 5 |
| Exact Mass | 424.981 Da |
| Monoisotopic Mass | 424.981 Da |
| Topological Polar Surface Area | 96.100 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 485.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
