GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.10mM in DMSO
Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Ginkgo (Ginkgo biloba) Plant Profile: bioactives, mechanism of action, references
Specifications
Sinónimos
Ginkgolide B | 15291-77-7 | Ginkolide B | Gingko lactone | BN 52021 | SR-01000597598 | bn52021 | Ginklide B | 7-Deoxyginkgolide C | C20H24O10 | CHEMBL266625 | SCHEMBL14279903 | 1-Hydroxy-(1beta)-Ginkgolide A | BCP25992 | NSC110257 | PDSP1_000734 | PDSP2_000724 | AKOS015895882 | NSC-110257 | t
Especificaciones y pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Primary constituent of Ginkgo biloba. Potential anticancer agent and neuroprotective.Platelet -activating factor (PAF) antagonist (K i = 1.3 μM). A biologically active terpenic lactone. Anti-inflammatory and neuroprotective effects in vivo. Inhibits ather
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
ANTAGONIST, CHANNEL BLOCKER
Mecanismo de acción
Channel blocker of 5-HT 3A;Channel blocker of 5-HT 3AB;Channel blocker of glycine receptor α1 subunit;Channel blocker of glycine receptor α2 subunit;Channel blocker of glycine receptor α3 subunit;Channel blocker of glycine receptor β subunit;Antagonist of
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Peso molecular
424.400 g/mol
XLogP3
-0.400
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
10
Rotatable Bond Count
1
Exact Mass
424.137 Da
Monoisotopic Mass
424.137 Da
Topological Polar Surface Area
149.000 Ų
Heavy Atom Count
30
Formal Charge
0
Complexity
925.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
11
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Referencias
1.Damu Lin, Hongqiang Wu, Zongwei Zhou, Zhenyu Tao, Tanghong Jia, Weiyang Gao. (2019) Ginkgolide B improves multiterritory perforator flap survival by inhibiting endoplasmic reticulum stress and oxidative stress. JOURNAL OF INVESTIGATIVE SURGERY, [PMID:31870195][10.1080/08941939.2019.1676483]
2.Lingling Wang, Xiuhua Zhao, Fengjian Yang, Weiwei Wu, Yanjie Liu, Li Wang, Lu Wang, Zijian Wang. (2019) Enhanced bioaccessibility in vitro and bioavailability of Ginkgo biloba extract nanoparticles prepared by liquid anti-solvent precipitation. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 54 (6):(2266-2276). [PMID:][10.1111/ijfs.14141]
3.Lingling Wang, Xiuhua Zhao, Yuangang Zu, Weiwei Wu, Yuanyuan Li, Chang Zu, Yin Zhang. (2016) Enhanced dissolution rate and oral bioavailability of ginkgo biloba extract by preparing nanoparticles via emulsion solvent evaporation combined with freeze drying (ESE-FR). RSC Advances, 6 (81):(77346-77357). [PMID:][10.1039/C6RA14771B]
4.Yuan Gang Zu, Lingling Wang, Xiuhua Zhao, Yuanyuan Li, Weiwei Wu, Chang Zu, Yannian Huang, Mingfang Wu, Ziqi Feng. (2016) Purification of Ginkgo biloba Extract by Antisolvent Recrystallization. CHEMICAL ENGINEERING & TECHNOLOGY, 39 (7):(1301-1308). [PMID:][10.1002/ceat.201500691]
Calculadoras de soluciones
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Reseñas
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