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FAPI-46 - ≥99% , CAS No.2374782-04-2

CAS: 2374782-04-2 Cat. No.: F650690 Peso molecular: 885.96 PubChem CID: 139400499
COA
FAPI-46 - ≥99% CAS No(2374782-04-2) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY ≥99%
Synonyms
2374782-04-2 | 59QC5DY68A | AKOS040757603 | FAPI-46 | SCHEMBL21257093 | MS-31645 | EX-A5968 | [10-[2-[4-[3-[[4-[[[2-[(2S)-2-Cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]methylamino]propyl]-1-piperazinyl]-2-oxoethyl]-1,4,7,10-
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
★
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5mg
F650690-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
1.800,90US$
10mg
F650690-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
3.300,90US$
Enter a quantity for the sizes you want to add.
Bulk / Custom
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Descripción general Specifications Nombres e identificadores Documentation Advanced Data Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas
🧪

Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

FAPI-46 is a quinoline-based fibroblast activation protein (FAP) -targeted radiotracer. FAPI-46 has higher tumor uptake and prolonged tumor accumulation. FAPI-46 can be used for tumor imaging of a multitude of different cancers

In Vitro

FAPI-46 (1-24 h) robustly binds to human FAP in human FAP-expressing HT-1080 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

FAPI-46 (i.v.) shows improved ratios of tumor to liver, kidney, and brain uptake, resulting in an enhanced image contrast for PET imaging . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:fibroblast activation protein (FAP)

Specifications

Sinónimos
2374782-04-2 | 59QC5DY68A | AKOS040757603 | FAPI-46 | SCHEMBL21257093 | MS-31645 | EX-A5968 | [10-[2-[4-[3-[[4-[[[2-[(2S)-2-Cyano-4, 4-difluoro-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]methylamino]propyl]-1-piperazinyl]-2-oxoethyl]-1, 4, 7, 10-
Especificaciones y pureza
≥99%
Mecanismos bioquímicos y fisiológicos
FAPI-46 is a quinoline-based fibroblast activation protein (FAP) -targeted radiotracer. FAPI-46 has higher tumor uptake and prolonged tumor accumulation. FAPI-46 can be used for tumor imaging of a multitude of different cancers.
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Desiccated
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥99%
Nombres e identificadores
Sonrisas canónicasCN(CCCN1CCN(CC1)C(=O)CN2CCN(CCN(CCN(CC2)CC(=O)O)CC(=O)O)CC(=O)O)C3=CC4=C(C=CN=C4C=C3)C(=O)NCC(=O)N5CC(CC5C#N)(F)F
IUPAC Name2-[4,7-bis(carboxymethyl)-10-[2-[4-[3-[[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-6-yl]-methylamino]propyl]piperazin-1-yl]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
InChIKeySDBGUEFOSXNKBX-HKBQPEDESA-N
INCHI1S/C41H57F2N11O9/c1-47(30-3-4-34-33(21-30)32(5-6-45-34)40(63)46-24-35(55)54-29-41(42,43)22-31(54)23-44)7-2-8-48-17-19-53(20-18-48)36(56)25-49-9-11-50(26-37(57)58)13-15-52(28-39(61)62)16-14-51(12-10-49)27-38(59)60/h3-6,21,31H,2,7-20,22,24-29H2,1H3,(H,46,63)(H,57,58)(H,59,60)(H,61,62)/t31-/m0/s1
Isómeros SMILES CN(CCCN1CCN(CC1)C(=O)CN2CCN(CCN(CCN(CC2)CC(=O)O)CC(=O)O)CC(=O)O)C3=CC4=C(C=CN=C4C=C3)C(=O)NCC(=O)N5CC(C[C@H]5C#N)(F)F
CAS alternativo 2374782-04-2
PubChem CID 139400499
Términos de entrada MeSH (68Ga)-FAPI-46;68Ga-FAPI-46;FAPI-46
Peso molecular 885.96

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadH2O : 100 mg/mL (112.87 mM; Need ultrasonic) DMSO : 100 mg/mL (112.87 mM; Need ultrasonic)
Calculadoras de soluciones
Reseñas

Reseñas de cliente

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