5-R-Rivaroxaban - ≥99% , CAS No.865479-71-6

CAS: 865479-71-6 Cat. No.: R127866 Peso molecular: 435.88 PubChem CID: 11524901

GRADE & PURITY ≥99%

Synonyms

BAY 59-7939 (Rivaroxaban) | Rivaroxaban R-isomer | BCP09021 | Rivaroxaban impurity A [EP] | BDBM13001 | 5-Chloro-N-({(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide | DTXSID20468042 | 2-Thiophenecarboxamide,

Storage

Conservar a -20°C

Shipped In

Hielera + almohadillas de hielo

Descripción general

5-R-Rivaroxaban es el enantiómero (R) de Rivaroxaban. Rivaroxabán (Xarelto; BAY 59-7939) es un nuevo inhibidor oral directo del Factor Xa (FXa) en fase avanzada de desarrollo para la prevención y el tratamiento de trastornos tromboembólicos.

Specifications

Sinónimos

BAY 59-7939 (Rivaroxaban) | Rivaroxaban R-isomer | BCP09021 | Rivaroxaban impurity A [EP] | BDBM13001 | 5-Chloro-N-({(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1, 3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide | DTXSID20468042 | 2-Thiophenecarboxamide,

Especificaciones y pureza

≥99%

Condiciones de almacenamiento de almacenamiento

Conservar a -20°C

Enviado en

Hielera + almohadillas de hielo

Tipo de acción

INHIBITOR

Pureza

≥99%

Nombres e identificadores

• Pubchem Sid: 504766518
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504766518
• Sonrisas canónicas: C1COCC(=O)N1C2=CC=C(C=C2)N3CC(OC3=O)CNC(=O)C4=CC=C(S4)Cl
• IUPAC Name: 5-chloro-N-[[(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
• InChIKey: KGFYHTZWPPHNLQ-CQSZACIVSA-N
• INCHI: 1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m1/s1
• Isómeros SMILES: C1COCC(=O)N1C2=CC=C(C=C2)N3C[C@H](OC3=O)CNC(=O)C4=CC=C(S4)Cl
• PubChem CID: 11524901
• Peso molecular: 435.88

Objetivos asociados (humanos)

F10 Tclin Coagulation factor X (13 Activities)

Discover Target: F10

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: DMSO
• Peso molecular: 435.900 g/mol
• XLogP3: 2.500
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 435.066 Da
• Monoisotopic Mass: 435.066 Da
• Topological Polar Surface Area: 116.000 Ų
• Heavy Atom Count: 29
• Formal Charge: 0
• Complexity: 645.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1