PPY A - ≥98%(HPLC) , CAS No.875634-01-8

CAS: 875634-01-8 Cat. No.: P287412 Molecular Weight: 372.42 PubChem CID: 16750094
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(HPLC)
Synonyms
5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-3-pyridinecarboxamide | 5-[3-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylpyridine-3-carboxamide
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
P287412-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$68.90
5mg
P287412-5mg
3
$243.90
10mg
P287412-10mg
3
$411.90
25mg
P287412-25mg
3
$875.90
50mg
P287412-50mg
2
$1,394.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2, 3-b]pyridin-5-yl]-N, N-dimethyl-3-pyridinecarboxamide | 5-[3-(2-methoxyphenyl)-1H-pyrrolo[2, 3-b]pyridin-5-yl]-N, N-dimethylpyridine-3-carboxamide
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent inhibitor of T315l mutant and wild-type Abl kinases (IC50values are 9 and 20 nM, respectively). Inhibits growth of cells transformed with either the Bcr-Abl T315l mutant or wild-type Bcr-Abl gene.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥98%(HPLC)
Names and Identifiers
Canonical SmilesCN(C)C(=O)C1=CN=CC(=C1)C2=CC3=C(NC=C3C4=CC=CC=C4OC)N=C2
IUPAC Name5-[3-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylpyridine-3-carboxamide
InChIKeyGYQRHHQPEMOLKH-UHFFFAOYSA-N
INCHI1S/C22H20N4O2/c1-26(2)22(27)16-8-14(10-23-11-16)15-9-18-19(13-25-21(18)24-12-15)17-6-4-5-7-20(17)28-3/h4-13H,1-3H3,(H,24,25)
Isomeric SMILES CN(C)C(=O)C1=CN=CC(=C1)C2=CC3=C(NC=C3C4=CC=CC=C4OC)N=C2
PubChem CID 16750094
Molecular Weight 372.42

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
ABL1 Tclin Tyrosine-protein kinase ABL1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
B2426276Certificate of AnalysisJan 16, 2024 P287412
B2426277Certificate of AnalysisJan 16, 2024 P287412
B2426278Certificate of AnalysisJan 16, 2024 P287412
B2426297Certificate of AnalysisJan 16, 2024 P287412
B2426298Certificate of AnalysisJan 16, 2024 P287412
B2426299Certificate of AnalysisJan 16, 2024 P287412
B2426300Certificate of AnalysisJan 16, 2024 P287412
B2426301Certificate of AnalysisJan 16, 2024 P287412
Chemical and Physical Properties
SolubilitySolvent:DMSO, Max Conc. mg/mL: 37.24, Max Conc. mM: 100
Molecular Weight372.400 g/mol
XLogP32.900
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass372.159 Da
Monoisotopic Mass372.159 Da
Topological Polar Surface Area71.100 Ų
Heavy Atom Count28
Formal Charge0
Complexity543.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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