Gonadotropins are key endocrine effectors of the hypothalamic–pituitary–gonadal (HPG) axis and mainly include follicle-stimulating hormone (FSH) and luteinizing hormone (LH), as well as the placental hormone human chorionic gonadotropin (hCG), which exerts LH-like activity.
Urinary follicle-stimulating hormone (uFSH) refers to follicle-stimulating hormone preparations extracted and purified from the urine of postmenopausal women.
Glycosylation is one of the most common—and most complex—post-translational modifications of proteins. It is ubiquitous in biologic drugs such as monoclonal antibodies (mAbs), fusion proteins, hormones (e.g., EPO), enzyme preparations, and components for cell/gene therapies (e.g., AAV capsid ...
One of the most common post-translational modifications of eukaryotic proteins is glycosylation. Glycosylation of proteins can affect many biological activities. For therapeutic glycoproteins, it can alter biological activity, targeting, transport, serum half-life, clearance and receptor ...
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