Thiocolchicine , CAS No.2730-71-4

  • ≥98%
Item Number
T340761
Grouped product items
SKUSizeAvailabilityPrice Qty
T340761-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$19.90
T340761-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
T340761-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$86.90
T340761-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$182.90
T340761-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
T340761-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$499.90

a specific tubulin synthesis inhibitor and Topo I inhibitor

Basic Description

SynonymsN-(1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide | 10-Demethoxy-10-methylthiocolchicine | Acetamide, N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]- | EINECS 220-346-8 | NC
Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Thiocolchicine is an inhibitor of microtubules by specific binding to tubulin. Modulator of axonal cytoskeleton. Induces apoptosis. Topo I (topoisomerase I) inhibitor.

AI Insight

Product Properties

Ki DataTubulin alpha chain: Ki= 0.7 μM (pig)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name N-[(7S)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
INCHI InChI=1S/C22H25NO5S/c1-12(24)23-16-8-6-13-10-18(26-2)21(27-3)22(28-4)20(13)14-7-9-19(29-5)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
InChi Key CMEGANPVAXDBPL-INIZCTEOSA-N
Canonical SMILES CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)OC
Isomeric SMILES CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)OC
RTECS GH0878800
PubChem CID 17648
Molecular Weight 415.50

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot NumberCertificate TypeDateItem
F2420406Certificate of AnalysisMar 01, 2024 T340761
F2420408Certificate of AnalysisMar 01, 2024 T340761
F2420410Certificate of AnalysisMar 01, 2024 T340761
F2420412Certificate of AnalysisMar 01, 2024 T340761
F2420415Certificate of AnalysisMar 01, 2024 T340761
F2420417Certificate of AnalysisMar 01, 2024 T340761
F2420420Certificate of AnalysisMar 01, 2024 T340761
F2420422Certificate of AnalysisMar 01, 2024 T340761
F2420424Certificate of AnalysisMar 01, 2024 T340761
F2420426Certificate of AnalysisMar 01, 2024 T340761
F2420428Certificate of AnalysisMar 01, 2024 T340761
F2420430Certificate of AnalysisMar 01, 2024 T340761

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Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS05
Signal Danger
Hazard Statements

H318:Causes serious eye damage

H300:Fatal if swallowed

H330:Fatal if inhaled

H340:May cause genetic defects

H300+H330:Fatal if swallowed or if inhaled

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P281:Use personal protective equipment as required.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P330:Rinse mouth.

P320:Specific treatment is urgent (see ... on this label).

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

P316:Get emergency medical help immediately.

RTECS GH0878800

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