TCS 2314 - 98%, high purity , CAS No.317353-73-4, Inhibitor of integrin α4β1

Item Number

T287170

Grouped product items
SKU	Size	Availability	Price
T287170-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$39.90
T287170-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$159.90
T287170-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$220.90
T287170-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$619.90
T287170-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$899.90

α4β1(VLA-4) antagonist

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Basic Description

Synonyms	2-[1-[(3S)-4-[2-[4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]morpholine-3-carbonyl]piperidin-4-yl]acetic acid
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Integrin very late antigen-4 (VLA-4;α4β1) antagonist (IC50= 4.4 nM). Blocks the activation of inflammatory cells.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of integrin α4β1
Product Description	TCS 2314 (compound 3) is a selective very late antigen-4 (VLA-4, α4β1, CD49d/CD29) antagonist with an IC50 of 4.4 nM

Names and Identifiers

IUPAC Name	2-[1-[(3S)-4-[2-[4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]morpholine-3-carbonyl]piperidin-4-yl]acetic acid
INCHI	InChI=1S/C28H34N4O6/c1-19-4-2-3-5-23(19)30-28(37)29-22-8-6-20(7-9-22)16-25(33)32-14-15-38-18-24(32)27(36)31-12-10-21(11-13-31)17-26(34)35/h2-9,21,24H,10-18H2,1H3,(H,34,35)(H2,29,30,37)/t24-/m0/s1
InChi Key	ITXAAOWFOURIHK-DEOSSOPVSA-N
Canonical SMILES	CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CC(=O)N3CCOCC3C(=O)N4CCC(CC4)CC(=O)O
Isomeric SMILES	CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CC(=O)N3CCOC[C@H]3C(=O)N4CCC(CC4)CC(=O)O
PubChem CID	11226207
Molecular Weight	522.59

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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10 results found

Lot Number	Certificate Type	Date	Item
C2512668	Certificate of Analysis	Oct 15, 2024	T287170
C2512669	Certificate of Analysis	Oct 15, 2024	T287170
C2512670	Certificate of Analysis	Oct 15, 2024	T287170
C2512671	Certificate of Analysis	Oct 15, 2024	T287170
C2512683	Certificate of Analysis	Oct 15, 2024	T287170
C2512684	Certificate of Analysis	Oct 15, 2024	T287170
C2512685	Certificate of Analysis	Oct 15, 2024	T287170
C2512686	Certificate of Analysis	Oct 15, 2024	T287170
C2512695	Certificate of Analysis	Oct 15, 2024	T287170
C2512696	Certificate of Analysis	Oct 15, 2024	T287170

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Basic Description