Sulforhodamine 101 - 10mM in DMSO, high purity , CAS No.60311-02-6

Item Number

S425010

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SKU	Size	Availability	Price	Qty
S425010-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$103.90

Red fluorophore standard for neurological staining and enzyme assays

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Basic Description

Synonyms	sulforhodamine 101 \| 60311-02-6 \| SR101 \| MFCD00012407 \| F9995-0524 \| 2-(3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaen-16-yl)-5-sulfobenzenesulfonate \| 9-(2,4-Disulfophenyl)-2,3,6,7,12,13,16,17-oct
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Red fluorophore standard for neurological staining and enzyme assays. Used as polar tracers for the studies of neuronal cell morphology and cell-cell communications.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	Sulforhodamine 101 is a red emitting fluorophore with an extinction coefficient of 105000. Sulforhodamine 101 is ideally used to label astrocytes in the rodent neocortex which can be observed with two-photon microscopy. In addition, Sulforhodamine 101 is used to determine morphological characteristics of astrocytes and to observe the association of astrocytes with the cortical microvasculature. Furthermore, this fluorophore is used as an activity-dependent dye for monitoring regulated exocytosis. Alternate studies suggest that Sulforhodamine 101 can increase intrinsic neuronal excitability and long-lasting increases in evoked EPSCs in CA1 pyramidal neurons in hippocampal slices. Sulforhodamine 101 enhances evoked synaptic N-methyl D-aspartate receptor (NMDAR) currents which can be blocked by the antagonist, AP-5. A red-emitting flurophore used to label astrocytes.

Names and Identifiers

IUPAC Name	2-(3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaen-16-yl)-5-sulfobenzenesulfonate
INCHI	InChI=1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)
InChi Key	COIVODZMVVUETJ-UHFFFAOYSA-N
Canonical SMILES	C1CC2=CC3=C(C4=C2N(C1)CCC4)OC5=C6CCC[N+]7=C6C(=CC5=C3C8=C(C=C(C=C8)S(=O)(=O)O)S(=O)(=O)[O-])CCC7
Isomeric SMILES	C1CC2=CC3=C(C4=C2N(C1)CCC4)OC5=C6CCC[N+]7=C6C(=CC5=C3C8=C(C=C(C=C8)S(=O)(=O)O)S(=O)(=O)[O-])CCC7
PubChem CID	122180
Molecular Weight	606.709
Beilstein	3582548

Citations of This Product

1. Feixiang Wang, Shengju Zhou, Youxin Zhang, Yijie Wang, Rui Guo, Haibin Xiao, Xiaofeng Sun. (2023) Chiral Phosphorescent Carbonized Polymer Dots Relayed Light-Harvesting System for Color-Tunable Circularly Polarized Room Temperature Phosphorescence. Small, (2306969). [PMID:37994220] [10.1002/smll.202306969]
2. Shiyi Che, Jie Wang, Xiaoyuan Ji, Zhiguo Su, Shaomin Wang, Songping Zhang. (2020) Positional assembly of multi-enzyme cascade reaction in polyelectrolyte doped microcapsule through electrospray and layer-by-layer assembly. Synthetic and Systems Biotechnology, 5 (206). [PMID:32671236] [10.1016/j.synbio.2020.06.010]
3. Wei Gu, Xueyu Pei, Yuxiao Cheng, Cuiling Zhang, Jidong Zhang, Yinghan Yan, Caiping Ding, Yuezhong Xian. (2017) Black Phosphorus Quantum Dots as the Ratiometric Fluorescence Probe for Trace Mercury Ion Detection Based on Inner Filter Effect. ACS Sensors, 2 (4): (576–582). [PMID:28723180] [10.1021/acssensors.7b00102]

References

1. Feixiang Wang, Shengju Zhou, Youxin Zhang, Yijie Wang, Rui Guo, Haibin Xiao, Xiaofeng Sun. (2023) Chiral Phosphorescent Carbonized Polymer Dots Relayed Light-Harvesting System for Color-Tunable Circularly Polarized Room Temperature Phosphorescence. Small, (2306969). [PMID:37994220] [10.1002/smll.202306969]
2. Shiyi Che, Jie Wang, Xiaoyuan Ji, Zhiguo Su, Shaomin Wang, Songping Zhang. (2020) Positional assembly of multi-enzyme cascade reaction in polyelectrolyte doped microcapsule through electrospray and layer-by-layer assembly. Synthetic and Systems Biotechnology, 5 (206). [PMID:32671236] [10.1016/j.synbio.2020.06.010]
3. Wei Gu, Xueyu Pei, Yuxiao Cheng, Cuiling Zhang, Jidong Zhang, Yinghan Yan, Caiping Ding, Yuezhong Xian. (2017) Black Phosphorus Quantum Dots as the Ratiometric Fluorescence Probe for Trace Mercury Ion Detection Based on Inner Filter Effect. ACS Sensors, 2 (4): (576–582). [PMID:28723180] [10.1021/acssensors.7b00102]

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Basic Description