Stafib-1 - 95%, high purity , CAS No.1688703-26-5

Item Number

S648578

Grouped product items
SKU	Size	Availability	Price
S648578-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$150.90
S648578-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$240.90
S648578-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$480.90
S648578-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$770.90
S648578-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,200.90

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Basic Description

Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a K i of 44 nM and an IC 50 of 154 nM.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a K i of 44 nM and an IC 50 of 154 nM In Vitro Stafib-1 is the first small molecule which inhibits the STAT5b SH2 domain with more than 50-fold selectivity over STAT5a. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:STAT5b 154 nM (IC 50 )

Names and Identifiers

IUPAC Name	[4-[[[2-[6-(phenylcarbamoyl)naphthalen-2-yl]oxyacetyl]amino]methyl]-2-phosphonooxyphenyl] dihydrogen phosphate
INCHI	InChI=1S/C26H24N2O11P2/c29-25(27-15-17-6-11-23(38-40(31,32)33)24(12-17)39-41(34,35)36)16-37-22-10-9-18-13-20(8-7-19(18)14-22)26(30)28-21-4-2-1-3-5-21/h1-14H,15-16H2,(H,27,29)(H,28,30)(H2,31,32,33)(H2,34,35,36)
InChi Key	SMUYYYBDKASIKY-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)OCC(=O)NCC4=CC(=C(C=C4)OP(=O)(O)O)OP(=O)(O)O
Isomeric SMILES	C1=CC=C(C=C1)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)OCC(=O)NCC4=CC(=C(C=C4)OP(=O)(O)O)OP(=O)(O)O
PubChem CID	122432036
Molecular Weight	602.42

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Basic Description