SR 9238 - ≥98%(HPLC), high purity , CAS No.1416153-62-2, Antagonist of Liver X receptor-α;Antagonist of Liver X receptor-β

Item Number

S288664

Grouped product items
SKU	Size	Availability	Price
S288664-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$114.90
S288664-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$229.90
S288664-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$398.90
S288664-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$558.90

Potent and selective LXR inverse agonist

View related series

Basic Description

Synonyms	Ethyl 5-((2,4,6-trimethyl-N-((3′-(methylsulfonyl)-[1,1′-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	Potent and selective LXR inverse agonist (IC50values are 43 and 214 nM for LXRβand LXRα, respectively). Selectively inhibits liver LXR over peripheral LXR. Exhibits selectivity for LXR over a panel of 20 other nuclear receptors, including FXR. Reduces hep
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of Liver X receptor-α;Antagonist of Liver X receptor-β

Names and Identifiers

IUPAC Name	ethyl 5-[[[4-(3-methylsulfonylphenyl)phenyl]methyl-(2,4,6-trimethylphenyl)sulfonylamino]methyl]furan-2-carboxylate
INCHI	InChI=1S/C31H33NO7S2/c1-6-38-31(33)29-15-14-27(39-29)20-32(41(36,37)30-22(3)16-21(2)17-23(30)4)19-24-10-12-25(13-11-24)26-8-7-9-28(18-26)40(5,34)35/h7-18H,6,19-20H2,1-5H3
InChi Key	HDZWHJYZJWLTAG-UHFFFAOYSA-N
Canonical SMILES	CCOC(=O)C1=CC=C(O1)CN(CC2=CC=C(C=C2)C3=CC(=CC=C3)S(=O)(=O)C)S(=O)(=O)C4=C(C=C(C=C4C)C)C
Isomeric SMILES	CCOC(=O)C1=CC=C(O1)CN(CC2=CC=C(C=C2)C3=CC(=CC=C3)S(=O)(=O)C)S(=O)(=O)C4=C(C=C(C=C4C)C)C
PubChem CID	71478195
MeSH Entry Terms	SR9238
Molecular Weight	595.73

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot Number	Certificate Type	Date	Item
B2426818	Certificate of Analysis	Jan 19, 2024	S288664
B2426828	Certificate of Analysis	Jan 19, 2024	S288664
B2426829	Certificate of Analysis	Jan 19, 2024	S288664
B2426830	Certificate of Analysis	Jan 19, 2024	S288664
B2426831	Certificate of Analysis	Jan 19, 2024	S288664
B2426832	Certificate of Analysis	Jan 19, 2024	S288664
B2426840	Certificate of Analysis	Jan 19, 2024	S288664
B2426841	Certificate of Analysis	Jan 19, 2024	S288664

Safety and Hazards(GHS)

Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
RIDADR	NONHforallmodesoftransport

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.

Basic Description