Basic Description

Synonyms	AS-35114 \| n1,n1'-(butane-1,4-diyl)dipropane-1,3-diamine \| 2FZ7Y3VOQX \| BPBio1_001086 \| SMR001397086 \| 1,4-Bis(aminopropyl)butanediamine \| N,Na?Bis(3-aminopropyl)-1,4-diaminobutane \| Q424597 \| HB0588 \| N,N''-bis(3-aminopropyl)butane-1,4-diamine \| N,N'-Bis
Specifications & Purity	Moligand™, for cell culture, ≥98%(GC)
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	for cell culture, Moligand™
Action Type	AGONIST, CHANNEL BLOCKER
Mechanism of action	Agonist of CaS receptor;Channel blocker of K ir2.1;Channel blocker of K ir2.3;Agonist of Retinoic acid receptor-α;Agonist of Retinoic acid receptor-β;Agonist of Retinoic acid receptor-γ;Channel blocker of TRPM4;Channel blocker of TRPM5;Channel blocker of
Product Description	Spermine is a biogenic polyamine formed from spermidine and occurs in almost all tissues. It is essential for both neoplastic and normal tissue growth and is involved in the modulation of calcium-dependent immune processes. Spermine inhibits NOS1 (nNOS). Spermine binds to and activates NMDA and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner. Spermine is a GluR inhibitor. A NOS1 inhibitor, NMDA activator, and GluR inhibitor.

AI Insight

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	N,N'-bis(3-aminopropyl)butane-1,4-diamine
INCHI	InChI=1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2
InChi Key	PFNFFQXMRSDOHW-UHFFFAOYSA-N
Canonical SMILES	C(CCNCCCN)CNCCCN
Isomeric SMILES	C(CCNCCCN)CNCCCN
WGK Germany	3
RTECS	EJ7175000
PubChem CID	1103
UN Number	3259
Molecular Weight	202.34
Beilstein	1750791

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

18 results found

Lot Number	Certificate Type	Date	Item
K2422314	Certificate of Analysis	Nov 25, 2024	S113079
I2207122	Certificate of Analysis	Jun 20, 2024	S113079
J2408657	Certificate of Analysis	Mar 29, 2024	S113079
L2319473	Certificate of Analysis	Dec 12, 2023	S113079
L2319172	Certificate of Analysis	Dec 12, 2023	S113079
A2221091	Certificate of Analysis	Nov 14, 2023	S113079
A2221090	Certificate of Analysis	Nov 14, 2023	S113079
I2405036	Certificate of Analysis	Jul 10, 2023	S113079
J2111066	Certificate of Analysis	Jul 10, 2023	S113079
J2111007	Certificate of Analysis	Jul 10, 2023	S113079
I2109145	Certificate of Analysis	Jun 15, 2023	S113079
C1925160	Certificate of Analysis	Nov 11, 2022	S113079
I2207118	Certificate of Analysis	Jul 28, 2022	S113079
I2207119	Certificate of Analysis	Jul 28, 2022	S113079
I2207120	Certificate of Analysis	Jul 28, 2022	S113079
I2207121	Certificate of Analysis	Jul 19, 2022	S113079
G2031089	Certificate of Analysis	Jun 14, 2022	S113079
A2221093	Certificate of Analysis	Dec 29, 2021	S113079

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Safety and Hazards(GHS)

Pictogram(s)	GHS05
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H411:Toxic to aquatic life with long lasting effects H317:May cause an allergic skin reaction H226:Flammable liquid and vapor H304:May be fatal if swallowed and enters airways
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P331:Do NOT induce vomiting. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	3
RTECS	EJ7175000

Alternative Products

Reviews

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Wan-Xue Li, Jing-Xiang Chen, Chuan-Chuan Zhang, Min-Shi Luo, Wen-Qing Zhang. (2024) Functional analysis of Ornithine decarboxylase in manipulating the wing dimorphism in Nilaparvata lugens (Stål) (Hemiptera: Delphacidae). JOURNAL OF INSECT PHYSIOLOGY, 152 (19): (104587). [PMID:38043786] [10.1016/j.jinsphys.2023.104587]
2. Junjun Wang, Yue Tang, Jia Zheng, Zhengmin Xie, Jianli Zhou, Yuangen Wu. (2024) DNAzyme-based and smartphone-assisted colorimetric biosensor for ultrasensitive and highly selective detection of histamine in meats. FOOD CHEMISTRY, 435 (13): (137526). [PMID:37742463] [10.1016/j.foodchem.2023.137526]
3. Zekun Shi, Yongning Wu, Xue Zhang, Yanyan Gao, Luqin Qiao, Qin Hou, Minglin Wang. (2023) Highly sensitive and selective colorimetric and fluorescent dual-readout assay for the analysis of spermine, spermidine and cysteine. DYES AND PIGMENTS, 220 (111659). [PMID:] [10.1016/j.dyepig.2023.111659]
4. Yeye Hu, Ziliang He, Ji Zhang, Chaohua Zhang, Yanting Wang, Wei Zhang, Fenglun Zhang, Weiming Zhang, Fenglin Gu, Weicheng Hu. (2023) Effect of Piper nigrum essential oil in dextran sulfate sodium (DSS)-induced colitis and its potential mechanisms. PHYTOMEDICINE, 119 (155024). [PMID:37597364] [10.1016/j.phymed.2023.155024]
5. Bobo Hu, Nana Zhang, Huihui Li, Chong Sun. (2021) A non-enzymatic Electrochemical Sensor Based on rGO-PPy for Rapid and Sensitive Determination of Histamine in Meat. International Journal of Electrochemical Science, 16 (210550). [PMID:37095754] [10.20964/2021.05.06]
6. Chunxia Zhang, Rongrong Liu, Xueping Kong, Hongwei Li, Dahai Yu, Xuexun Fang, Lixin Wu, Yuqing Wu. (2023) Adaptive Responses of a Peroxidase-like Polyoxometalate-Based Tri-Assembly to Bacterial Microenvironment (BME) Significantly Improved the Anti-Bacterial Effects. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (10): (8858). [PMID:37240203] [10.3390/ijms24108858]
7. Nuo Duan, Kexin Ren, Mingqian Song, Xinyue Zhang, Zhouping Wang, Fei Jia, Shijia Wu. (2023) A dual-donor FRET based aptamer sensor for simultaneous determination of histamine and tyramine in fishes. MICROCHEMICAL JOURNAL, 191 (108801). [PMID:] [10.1016/j.microc.2023.108801]
8. Si Lin, Hou Juying, Lv Wei, Hou Qin, Xu Zhixiang, Ai Shiyun. (2023) An intelligent fluorescence platform based on lignocellulose components and fluorescein for food freshness monitoring. Biomass Conversion and Biorefinery, (1-11). [PMID:] [10.1007/s13399-023-03879-6]
9. Wenyang Zhang, Da-Wen Sun, Ji Ma, Anjun Qin, Ben Zhong Tang. (2023) A ratiometric fluorescent tag based on dual-emissive hydrophobic carbon dots for in-situ monitoring of seafood freshness. ANALYTICA CHIMICA ACTA, 1250 (340931). [PMID:36898807] [10.1016/j.aca.2023.340931]
10. Wang Tingting, Chen Yihui, Hou Chunyan, Qiao Xiaoqiang. (2023) PEG-modified halloysite as a hydrophilic interaction and cation exchange mixed-mode sorbent for solid-phase extraction of biogenic amines in fish samples. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (18): (4265-4275). [PMID:36422664] [10.1007/s00216-022-04441-5]
11. Guoqing Wang, Xinyue Meng, Peiyan Wang, Xinping Wang, Gaoli Liu, Dong-An Wang, Changjiang Fan. (2022) A catechol bioadhesive for rapid hemostasis and healing of traumatic internal organs and major arteries. BIOMATERIALS, 291 (121908). [PMID:36384085] [10.1016/j.biomaterials.2022.121908]
12. Yuan-Fu Ding, Jianwen Wei, Xingping Quan, Wenting Gu, Long Xi, Ying Zheng, Yonghua Zhao, Jingwei Luo, Shengke Li, Greta S.P. Mok, Ruibing Wang. (2022) Hyaluronic acid-based supramolecular medicine with polyamines sequestration capability for cooperative anti-psoriasis. CARBOHYDRATE POLYMERS, 296 (119968). [PMID:36088007] [10.1016/j.carbpol.2022.119968]
13. Jianfeng Yan, Quanbin Fu, Shikai Zhang, Yu Liu, Xianbao Shi, Juying Hou, Junling Duan, Shiyun Ai. (2022) A sensitive ratiometric fluorescent sensor based on carbon dots and CdTe quantum dots for visual detection of biogenic amines in food samples. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 282 (121706). [PMID:35933782] [10.1016/j.saa.2022.121706]
14. Liu Dehong, Shi Hongjie, Chen Guanglin, Zhang Xu, Gu Tingyue, Zhu Minglong, Tan Wensong. (2022) Strategies for anti-oxidative stress and anti-acid stress in bioleaching of LiCoO2 using an acidophilic microbial consortium. EXTREMOPHILES, 26 (2): (1-16). [PMID:35767155] [10.1007/s00792-022-01270-3]
15. Lancheng Wang, Mingjie Xu, Huimin Zhou, Kun Yan, Shiqi Duan, Dandan Xue, Youmei Wang, Bin Di, Chi Hu. (2022) Teaching PCR for Simultaneous Sensing of Gene Transcription and Downstream Metabolites by Cucurbit[8]uril-Mediated Intervention of Polymerase Activity. ANALYTICAL CHEMISTRY, 94 (24): (8715–8723). [PMID:35671188] [10.1021/acs.analchem.2c01103]
16. Yujuan Qin, Pengcheng Huang, Fang-Ying Wu. (2022) Histamine-responsive dye-incorporated carbon dots for visual monitoring of food spoilage. SENSORS AND ACTUATORS B-CHEMICAL, 365 (131911). [PMID:] [10.1016/j.snb.2022.131911]
17. Qianqian Zhang, Jianwei Bao, Tijie Duan, Minxing Hu, Yuting He, Junwei Wang, Rongfeng Hu, Jihui Tang. (2022) Nanomicelle-Microsphere Composite as a Drug Carrier to Improve Lung-Targeting Specificity for Lung Cancer. Pharmaceutics, 14 (3): (510). [PMID:35335884] [10.3390/pharmaceutics14030510]
18. Xu Xu, Jiaxin Gao, Di Cao, Xiang Li, Xin Zhao, Shuang Yue, Lei Zhang. (2022) Designed 3D N-doped magnetic porous carbon spheres for sensitive monitoring of biogenic amine by simultaneous microwave-assisted derivatization and magnetic-solid phase extraction. JOURNAL OF CHROMATOGRAPHY A, 1667 (462882). [PMID:35149412] [10.1016/j.chroma.2022.462882]
19. Xinxiu Ma, Jingran Bi, Xinyu Li, Gongliang Zhang, Hongshun Hao, Hongman Hou. (2021) Contribution of Microorganisms to Biogenic Amine Accumulation during Fish Sauce Fermentation and Screening of Novel Starters. Foods, 10 (11): (2572). [PMID:34828853] [10.3390/foods10112572]
20. Yongliang Guo, Lili Tian, Jiangming Wu, Yang Wu, Yongmei Liu, Jie Du, Xiaoquan Lu. (2021) A Highly Sensitive Electrochemiluminescence Spermine Biosensor Based on Au−Ag Bimetallic Nanoclusters. ELECTROANALYSIS, 33 (9): (2016-2024). [PMID:] [10.1002/elan.202100169]
21. Zongyan Quan, Hui He, Hang Zhou, Yuting Liang, Lei Wang, Songya Tian, Hongxiang Zhu, Shuangfei Wang. (2021) Designing an intelligent nanofiber ratiometric fluorescent sensor sensitive to biogenic amines for detecting the freshness of shrimp and pork. SENSORS AND ACTUATORS B-CHEMICAL, 333 (129535). [PMID:] [10.1016/j.snb.2021.129535]
22. Yu Wang, Xudong Zhao, Bingyang Huo, Shuyue Ren, Jialei Bai, Yuan Peng, Shuang Li, Dianpeng Han, Jiang Wang, Tie Han, Zhixian Gao. (2021) Sensitive Fluorescence Aptasensor Based on Hybridization Chain Reaction with Upconversion Nanoparticles by Triplex DNA Formation for Bisphenol A Detection. ACS Applied Bio Materials, 4 (1): (763–769). [PMID:] [10.1021/acsabm.0c01347]
23. Xin Li, Xiao-wen Jiang, Hai-xiao Chu, Qing-chun Zhao, Huai-wei Ding, Chao-hong Cai. (2021) Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition. Chinese Herbal Medicines, 13 (105). [PMID:36117765] [10.1016/j.chmed.2020.12.004]
24. Yi-Fang Li, Zheng-Zhong Lin, Cheng-Yi Hong, Zhi-Yong Huang. (2021) Histamine detection in fish samples based on indirect competitive ELISA method using iron-cobalt co-doped carbon dots labeled histamine antibody. FOOD CHEMISTRY, 345 (128812). [PMID:33601655] [10.1016/j.foodchem.2020.128812]
25. Tan Xiao-Hui, Li Yu-Bin, Liao Yan, Liu Hua-Zhong. (2020) An enzyme free fluorescence resonance transfer strategy based on hybrid chain reaction and triplex DNA for Vibrio parahaemolyticus. Scientific Reports, 10 (1): (1-8). [PMID:33244061] [10.1038/s41598-020-77913-2]
26. Zhongjuan Wang, Yueqin Liang, Yanqiu Liu, Hongying Xia, Jianqi Liu, Xingfang Jin, Zhongkun Li. (2020) The pH-triggered polyglutamate brush co-delivery of MDR1 and survivin-targeting siRNAs efficiently overcomes multi-drug resistance of NSCLC. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, [PMID:32924641] [10.1080/03639045.2020.1822860]
27. Yan Zhou, Jia Liu, Tingting Zheng, Yang Tian. (2020) Label-Free SERS Strategy for In Situ Monitoring and Real-Time Imaging of Aβ Aggregation Process in Live Neurons and Brain Tissues. ANALYTICAL CHEMISTRY, 92 (8): (5910–5920). [PMID:32227892] [10.1021/acs.analchem.9b05837]
28. Hailong Sun, Shuangping Liu, Jieqi Mao, Ziwei Yu, Zhijie Lin, Jian Mao. (2020) New insights into the impacts of huangjiu compontents on intoxication. FOOD CHEMISTRY, 317 (126420). [PMID:32101783] [10.1016/j.foodchem.2020.126420]
29. Huili Tian, Nuo Duan, Shijia Wu, Zhouping Wang. (2019) Selection and application of ssDNA aptamers against spermine based on Capture-SELEX. ANALYTICA CHIMICA ACTA, 1081 (168). [PMID:31446954] [10.1016/j.aca.2019.07.031]
30. Xiaoguang Ying, Anshun Kang, Xiaomei Zhu, Xiao Li. (2019) Molecular imprint enhanced specific adsorption visualization on electrospun chromogenic membrane for efficient detection of putrescine. JOURNAL OF APPLIED POLYMER SCIENCE, 136 (45): (48186). [PMID:] [10.1002/app.48186]
31. Ruidi Shen, Li Zou, Shixin Wu, Tingting Li, Jing Wang, Jianmin Liu, Liansheng Ling. (2019) A novel label-free fluorescent detection of histidine based upon Cu2+-specific DNAzyme and hybridization chain reaction. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 213 (42). [PMID:30682646] [10.1016/j.saa.2019.01.062]
32. Jing Wang, Tingting Li, Haigang Li, Gongke Li, Shixin Wu, Liansheng Ling. (2019) A universal colorimetric PCR biosensor based upon triplex formation with the aid of Ru(phen)2dppx2+. SENSORS AND ACTUATORS B-CHEMICAL, 278 (39). [PMID:] [10.1016/j.snb.2018.09.055]
33. Wang Jing, Li Haigang, Li Tingting, Ling Liansheng. (2018) Determination of bacterial DNA based on catalytic oxidation of cysteine by G-quadruplex DNAzyme generated from asymmetric PCR: Application to the colorimetric detection of Staphylococcus aureus. MICROCHIMICA ACTA, 185 (9): (1-9). [PMID:30099608] [10.1007/s00604-018-2935-y]
34. Li Zou, Tingting Li, Ruidi Shen, Shaozhi Ren, Liansheng Ling. (2018) A label-free light-up fluorescent sensing platform based upon hybridization chain reaction amplification and DNA triplex assembly. TALANTA, 189 (137). [PMID:30086897] [10.1016/j.talanta.2018.06.051]
35. Wang Hongwei, Li Xiaoxi, Chen Ling, Huang Xiaoyi, Li Lin. (2017) Cationic starch/pDNA nanocomplexes assembly and their nanostructure changes on gene transfection efficiency. Scientific Reports, 7 (1): (1-12). [PMID:29093552] [10.1038/s41598-017-14551-1]
36. Yonghui Nie, Yuanjie Teng, Pan Li, Wenhan Liu, Qianwei Shi, Yuchao Zhang. (2018) Label-free aptamer-based sensor for specific detection of malathion residues by surface-enhanced Raman scattering. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 191 (271). [PMID:29045930] [10.1016/j.saa.2017.10.030]
37. Xin Ji, Huilong Guo, Qiao Tang, Dong Ma, Wei Xue. (2017) A targeted nanocarrier based on polyspermine for the effective delivery of methotrexate in nasopharyngeal carcinoma. Materials Science & Engineering C-Materials for Biological Applications, 81 (48). [PMID:28888001] [10.1016/j.msec.2017.07.036]
38. Xiaoyi Huang, Xiaoxi Li, Ling Chen, Lin Li. (2017) Spermine modified starch-based carrier for gene delivery: Structure-transfection activity relationships. CARBOHYDRATE POLYMERS, 173 (690). [PMID:28732914] [10.1016/j.carbpol.2017.05.099]
39. Meng Li Liu, Bin Bin Chen, Ze Xi Liu, Cheng Zhi Huang. (2016) Highly selective and sensitive detection of 2,4,6-trinitrophenol by using newly developed blue–green photoluminescent carbon nanodots. TALANTA, 161 (875). [PMID:27769497] [10.1016/j.talanta.2016.08.046]
40. Xiangmin Miao, Zongbing Li, Liansheng Ling. (2016) Fluorescence recognition of double-stranded DNA based on the quenching of gold nanoparticles to a fluorophore labeled DNA probe. ANALYST, 141 (20): (5829-5834). [PMID:27508282] [10.1039/C6AN01145D]
41. Zhongjuan Wang, Haijuan Zou, Zirui Wang, Jiamin Wu, Zhongsheng Xia, Min Feng. (2016) Highly stable polyglutamate derivatives/siRNA polyplex efficiently down-relegate survivin expression and augment the efficacy of cisplatin. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 505 (24). [PMID:27039150] [10.1016/j.ijpharm.2016.03.062]
42. Chen Ying, Huang Liyong, Zhang Huiyong, Diao Xiling, Zhao Shuyang, Zhou Wenke. (2017) Reduction in Autophagy by (-)-Epigallocatechin-3-Gallate (EGCG): a Potential Mechanism of Prevention of Mitochondrial Dysfunction After Subarachnoid Hemorrhage. MOLECULAR NEUROBIOLOGY, 54 (1): (392-405). [PMID:26742518] [10.1007/s12035-015-9629-9]
43. Yuefang Zhao, Yuting Qin, Yang Liang, Haijuan Zou, Xiao Peng, Huan Huang, Ming Lu, Min Feng. (2013) Salt-Induced Stability and Serum-Resistance of Polyglutamate Polyelectrolyte Brushes/Nuclear Factor-κB p65 siRNA Polyplex Enhance the Apoptosis and Efficacy of Doxorubicin. BIOMACROMOLECULES, 14 (6): (1777–1786). [PMID:23617546] [10.1021/bm400177q]

References

1. Charton J, Deprez-Poulain R, Hennuyer N, Tailleux A, Staels B, Deprez B. (2009) Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.. Bioorg Med Chem Lett, 19 (2): (489-92). [PMID:19058965] [10.1021/op500134e]
2. Wang W, Yang J, Liu H, Lu D, Chen X, Zenonos Z, Campos LS, Rad R, Guo G, Zhang S et al.. (2011) Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1.. Proc Natl Acad Sci USA, 108 (45): (18283-8). [PMID:21990348] [10.1021/op500134e]
3. Wan-Xue Li, Jing-Xiang Chen, Chuan-Chuan Zhang, Min-Shi Luo, Wen-Qing Zhang. (2024) Functional analysis of Ornithine decarboxylase in manipulating the wing dimorphism in Nilaparvata lugens (Stål) (Hemiptera: Delphacidae). JOURNAL OF INSECT PHYSIOLOGY, 152 (19): (104587). [PMID:38043786] [10.1016/j.jinsphys.2023.104587]
4. Junjun Wang, Yue Tang, Jia Zheng, Zhengmin Xie, Jianli Zhou, Yuangen Wu. (2024) DNAzyme-based and smartphone-assisted colorimetric biosensor for ultrasensitive and highly selective detection of histamine in meats. FOOD CHEMISTRY, 435 (13): (137526). [PMID:37742463] [10.1016/j.foodchem.2023.137526]
5. Zekun Shi, Yongning Wu, Xue Zhang, Yanyan Gao, Luqin Qiao, Qin Hou, Minglin Wang. (2023) Highly sensitive and selective colorimetric and fluorescent dual-readout assay for the analysis of spermine, spermidine and cysteine. DYES AND PIGMENTS, 220 (111659). [PMID:] [10.1016/j.dyepig.2023.111659]
6. Yeye Hu, Ziliang He, Ji Zhang, Chaohua Zhang, Yanting Wang, Wei Zhang, Fenglun Zhang, Weiming Zhang, Fenglin Gu, Weicheng Hu. (2023) Effect of Piper nigrum essential oil in dextran sulfate sodium (DSS)-induced colitis and its potential mechanisms. PHYTOMEDICINE, 119 (155024). [PMID:37597364] [10.1016/j.phymed.2023.155024]
7. Bobo Hu, Nana Zhang, Huihui Li, Chong Sun. (2021) A non-enzymatic Electrochemical Sensor Based on rGO-PPy for Rapid and Sensitive Determination of Histamine in Meat. International Journal of Electrochemical Science, 16 (210550). [PMID:37095754] [10.20964/2021.05.06]
8. Chunxia Zhang, Rongrong Liu, Xueping Kong, Hongwei Li, Dahai Yu, Xuexun Fang, Lixin Wu, Yuqing Wu. (2023) Adaptive Responses of a Peroxidase-like Polyoxometalate-Based Tri-Assembly to Bacterial Microenvironment (BME) Significantly Improved the Anti-Bacterial Effects. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (10): (8858). [PMID:37240203] [10.3390/ijms24108858]
9. Nuo Duan, Kexin Ren, Mingqian Song, Xinyue Zhang, Zhouping Wang, Fei Jia, Shijia Wu. (2023) A dual-donor FRET based aptamer sensor for simultaneous determination of histamine and tyramine in fishes. MICROCHEMICAL JOURNAL, 191 (108801). [PMID:] [10.1016/j.microc.2023.108801]
10. Si Lin, Hou Juying, Lv Wei, Hou Qin, Xu Zhixiang, Ai Shiyun. (2023) An intelligent fluorescence platform based on lignocellulose components and fluorescein for food freshness monitoring. Biomass Conversion and Biorefinery, (1-11). [PMID:] [10.1007/s13399-023-03879-6]
11. Wenyang Zhang, Da-Wen Sun, Ji Ma, Anjun Qin, Ben Zhong Tang. (2023) A ratiometric fluorescent tag based on dual-emissive hydrophobic carbon dots for in-situ monitoring of seafood freshness. ANALYTICA CHIMICA ACTA, 1250 (340931). [PMID:36898807] [10.1016/j.aca.2023.340931]
12. Wang Tingting, Chen Yihui, Hou Chunyan, Qiao Xiaoqiang. (2023) PEG-modified halloysite as a hydrophilic interaction and cation exchange mixed-mode sorbent for solid-phase extraction of biogenic amines in fish samples. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (18): (4265-4275). [PMID:36422664] [10.1007/s00216-022-04441-5]
13. Guoqing Wang, Xinyue Meng, Peiyan Wang, Xinping Wang, Gaoli Liu, Dong-An Wang, Changjiang Fan. (2022) A catechol bioadhesive for rapid hemostasis and healing of traumatic internal organs and major arteries. BIOMATERIALS, 291 (121908). [PMID:36384085] [10.1016/j.biomaterials.2022.121908]
14. Yuan-Fu Ding, Jianwen Wei, Xingping Quan, Wenting Gu, Long Xi, Ying Zheng, Yonghua Zhao, Jingwei Luo, Shengke Li, Greta S.P. Mok, Ruibing Wang. (2022) Hyaluronic acid-based supramolecular medicine with polyamines sequestration capability for cooperative anti-psoriasis. CARBOHYDRATE POLYMERS, 296 (119968). [PMID:36088007] [10.1016/j.carbpol.2022.119968]
15. Jianfeng Yan, Quanbin Fu, Shikai Zhang, Yu Liu, Xianbao Shi, Juying Hou, Junling Duan, Shiyun Ai. (2022) A sensitive ratiometric fluorescent sensor based on carbon dots and CdTe quantum dots for visual detection of biogenic amines in food samples. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 282 (121706). [PMID:35933782] [10.1016/j.saa.2022.121706]
16. Liu Dehong, Shi Hongjie, Chen Guanglin, Zhang Xu, Gu Tingyue, Zhu Minglong, Tan Wensong. (2022) Strategies for anti-oxidative stress and anti-acid stress in bioleaching of LiCoO2 using an acidophilic microbial consortium. EXTREMOPHILES, 26 (2): (1-16). [PMID:35767155] [10.1007/s00792-022-01270-3]
17. Lancheng Wang, Mingjie Xu, Huimin Zhou, Kun Yan, Shiqi Duan, Dandan Xue, Youmei Wang, Bin Di, Chi Hu. (2022) Teaching PCR for Simultaneous Sensing of Gene Transcription and Downstream Metabolites by Cucurbit[8]uril-Mediated Intervention of Polymerase Activity. ANALYTICAL CHEMISTRY, 94 (24): (8715–8723). [PMID:35671188] [10.1021/acs.analchem.2c01103]
18. Yujuan Qin, Pengcheng Huang, Fang-Ying Wu. (2022) Histamine-responsive dye-incorporated carbon dots for visual monitoring of food spoilage. SENSORS AND ACTUATORS B-CHEMICAL, 365 (131911). [PMID:] [10.1016/j.snb.2022.131911]
19. Qianqian Zhang, Jianwei Bao, Tijie Duan, Minxing Hu, Yuting He, Junwei Wang, Rongfeng Hu, Jihui Tang. (2022) Nanomicelle-Microsphere Composite as a Drug Carrier to Improve Lung-Targeting Specificity for Lung Cancer. Pharmaceutics, 14 (3): (510). [PMID:35335884] [10.3390/pharmaceutics14030510]
20. Xu Xu, Jiaxin Gao, Di Cao, Xiang Li, Xin Zhao, Shuang Yue, Lei Zhang. (2022) Designed 3D N-doped magnetic porous carbon spheres for sensitive monitoring of biogenic amine by simultaneous microwave-assisted derivatization and magnetic-solid phase extraction. JOURNAL OF CHROMATOGRAPHY A, 1667 (462882). [PMID:35149412] [10.1016/j.chroma.2022.462882]
21. Xinxiu Ma, Jingran Bi, Xinyu Li, Gongliang Zhang, Hongshun Hao, Hongman Hou. (2021) Contribution of Microorganisms to Biogenic Amine Accumulation during Fish Sauce Fermentation and Screening of Novel Starters. Foods, 10 (11): (2572). [PMID:34828853] [10.3390/foods10112572]
22. Yongliang Guo, Lili Tian, Jiangming Wu, Yang Wu, Yongmei Liu, Jie Du, Xiaoquan Lu. (2021) A Highly Sensitive Electrochemiluminescence Spermine Biosensor Based on Au−Ag Bimetallic Nanoclusters. ELECTROANALYSIS, 33 (9): (2016-2024). [PMID:] [10.1002/elan.202100169]
23. Zongyan Quan, Hui He, Hang Zhou, Yuting Liang, Lei Wang, Songya Tian, Hongxiang Zhu, Shuangfei Wang. (2021) Designing an intelligent nanofiber ratiometric fluorescent sensor sensitive to biogenic amines for detecting the freshness of shrimp and pork. SENSORS AND ACTUATORS B-CHEMICAL, 333 (129535). [PMID:] [10.1016/j.snb.2021.129535]
24. Yu Wang, Xudong Zhao, Bingyang Huo, Shuyue Ren, Jialei Bai, Yuan Peng, Shuang Li, Dianpeng Han, Jiang Wang, Tie Han, Zhixian Gao. (2021) Sensitive Fluorescence Aptasensor Based on Hybridization Chain Reaction with Upconversion Nanoparticles by Triplex DNA Formation for Bisphenol A Detection. ACS Applied Bio Materials, 4 (1): (763–769). [PMID:] [10.1021/acsabm.0c01347]
25. Xin Li, Xiao-wen Jiang, Hai-xiao Chu, Qing-chun Zhao, Huai-wei Ding, Chao-hong Cai. (2021) Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition. Chinese Herbal Medicines, 13 (105). [PMID:36117765] [10.1016/j.chmed.2020.12.004]
26. Yi-Fang Li, Zheng-Zhong Lin, Cheng-Yi Hong, Zhi-Yong Huang. (2021) Histamine detection in fish samples based on indirect competitive ELISA method using iron-cobalt co-doped carbon dots labeled histamine antibody. FOOD CHEMISTRY, 345 (128812). [PMID:33601655] [10.1016/j.foodchem.2020.128812]
27. Tan Xiao-Hui, Li Yu-Bin, Liao Yan, Liu Hua-Zhong. (2020) An enzyme free fluorescence resonance transfer strategy based on hybrid chain reaction and triplex DNA for Vibrio parahaemolyticus. Scientific Reports, 10 (1): (1-8). [PMID:33244061] [10.1038/s41598-020-77913-2]
28. Zhongjuan Wang, Yueqin Liang, Yanqiu Liu, Hongying Xia, Jianqi Liu, Xingfang Jin, Zhongkun Li. (2020) The pH-triggered polyglutamate brush co-delivery of MDR1 and survivin-targeting siRNAs efficiently overcomes multi-drug resistance of NSCLC. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, [PMID:32924641] [10.1080/03639045.2020.1822860]
29. Yan Zhou, Jia Liu, Tingting Zheng, Yang Tian. (2020) Label-Free SERS Strategy for In Situ Monitoring and Real-Time Imaging of Aβ Aggregation Process in Live Neurons and Brain Tissues. ANALYTICAL CHEMISTRY, 92 (8): (5910–5920). [PMID:32227892] [10.1021/acs.analchem.9b05837]
30. Hailong Sun, Shuangping Liu, Jieqi Mao, Ziwei Yu, Zhijie Lin, Jian Mao. (2020) New insights into the impacts of huangjiu compontents on intoxication. FOOD CHEMISTRY, 317 (126420). [PMID:32101783] [10.1016/j.foodchem.2020.126420]
31. Huili Tian, Nuo Duan, Shijia Wu, Zhouping Wang. (2019) Selection and application of ssDNA aptamers against spermine based on Capture-SELEX. ANALYTICA CHIMICA ACTA, 1081 (168). [PMID:31446954] [10.1016/j.aca.2019.07.031]
32. Xiaoguang Ying, Anshun Kang, Xiaomei Zhu, Xiao Li. (2019) Molecular imprint enhanced specific adsorption visualization on electrospun chromogenic membrane for efficient detection of putrescine. JOURNAL OF APPLIED POLYMER SCIENCE, 136 (45): (48186). [PMID:] [10.1002/app.48186]
33. Ruidi Shen, Li Zou, Shixin Wu, Tingting Li, Jing Wang, Jianmin Liu, Liansheng Ling. (2019) A novel label-free fluorescent detection of histidine based upon Cu2+-specific DNAzyme and hybridization chain reaction. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 213 (42). [PMID:30682646] [10.1016/j.saa.2019.01.062]
34. Jing Wang, Tingting Li, Haigang Li, Gongke Li, Shixin Wu, Liansheng Ling. (2019) A universal colorimetric PCR biosensor based upon triplex formation with the aid of Ru(phen)2dppx2+. SENSORS AND ACTUATORS B-CHEMICAL, 278 (39). [PMID:] [10.1016/j.snb.2018.09.055]
35. Wang Jing, Li Haigang, Li Tingting, Ling Liansheng. (2018) Determination of bacterial DNA based on catalytic oxidation of cysteine by G-quadruplex DNAzyme generated from asymmetric PCR: Application to the colorimetric detection of Staphylococcus aureus. MICROCHIMICA ACTA, 185 (9): (1-9). [PMID:30099608] [10.1007/s00604-018-2935-y]
36. Li Zou, Tingting Li, Ruidi Shen, Shaozhi Ren, Liansheng Ling. (2018) A label-free light-up fluorescent sensing platform based upon hybridization chain reaction amplification and DNA triplex assembly. TALANTA, 189 (137). [PMID:30086897] [10.1016/j.talanta.2018.06.051]
37. Wang Hongwei, Li Xiaoxi, Chen Ling, Huang Xiaoyi, Li Lin. (2017) Cationic starch/pDNA nanocomplexes assembly and their nanostructure changes on gene transfection efficiency. Scientific Reports, 7 (1): (1-12). [PMID:29093552] [10.1038/s41598-017-14551-1]
38. Yonghui Nie, Yuanjie Teng, Pan Li, Wenhan Liu, Qianwei Shi, Yuchao Zhang. (2018) Label-free aptamer-based sensor for specific detection of malathion residues by surface-enhanced Raman scattering. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 191 (271). [PMID:29045930] [10.1016/j.saa.2017.10.030]
39. Xin Ji, Huilong Guo, Qiao Tang, Dong Ma, Wei Xue. (2017) A targeted nanocarrier based on polyspermine for the effective delivery of methotrexate in nasopharyngeal carcinoma. Materials Science & Engineering C-Materials for Biological Applications, 81 (48). [PMID:28888001] [10.1016/j.msec.2017.07.036]
40. Xiaoyi Huang, Xiaoxi Li, Ling Chen, Lin Li. (2017) Spermine modified starch-based carrier for gene delivery: Structure-transfection activity relationships. CARBOHYDRATE POLYMERS, 173 (690). [PMID:28732914] [10.1016/j.carbpol.2017.05.099]
41. Meng Li Liu, Bin Bin Chen, Ze Xi Liu, Cheng Zhi Huang. (2016) Highly selective and sensitive detection of 2,4,6-trinitrophenol by using newly developed blue–green photoluminescent carbon nanodots. TALANTA, 161 (875). [PMID:27769497] [10.1016/j.talanta.2016.08.046]
42. Xiangmin Miao, Zongbing Li, Liansheng Ling. (2016) Fluorescence recognition of double-stranded DNA based on the quenching of gold nanoparticles to a fluorophore labeled DNA probe. ANALYST, 141 (20): (5829-5834). [PMID:27508282] [10.1039/C6AN01145D]
43. Zhongjuan Wang, Haijuan Zou, Zirui Wang, Jiamin Wu, Zhongsheng Xia, Min Feng. (2016) Highly stable polyglutamate derivatives/siRNA polyplex efficiently down-relegate survivin expression and augment the efficacy of cisplatin. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 505 (24). [PMID:27039150] [10.1016/j.ijpharm.2016.03.062]
44. Chen Ying, Huang Liyong, Zhang Huiyong, Diao Xiling, Zhao Shuyang, Zhou Wenke. (2017) Reduction in Autophagy by (-)-Epigallocatechin-3-Gallate (EGCG): a Potential Mechanism of Prevention of Mitochondrial Dysfunction After Subarachnoid Hemorrhage. MOLECULAR NEUROBIOLOGY, 54 (1): (392-405). [PMID:26742518] [10.1007/s12035-015-9629-9]
45. Yuefang Zhao, Yuting Qin, Yang Liang, Haijuan Zou, Xiao Peng, Huan Huang, Ming Lu, Min Feng. (2013) Salt-Induced Stability and Serum-Resistance of Polyglutamate Polyelectrolyte Brushes/Nuclear Factor-κB p65 siRNA Polyplex Enhance the Apoptosis and Efficacy of Doxorubicin. BIOMACROMOLECULES, 14 (6): (1777–1786). [PMID:23617546] [10.1021/bm400177q]

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