| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| T134625-1g | 1g | 3 | $11.90 | |
| T134625-5g | 5g | 5 | $34.90 | |
| T134625-25g | 25g | 3 | $121.90 | |
| T134625-100g | 100g | 1 | $339.90 |
| Synonyms | Taurocholic acid sodium salt hydrate | WOX5F63THK | Sodium taurocholate hydrate | MLS002153446 | Sodium taurocholate dihydrate | sodium taurocholate monohydrate | Taurocholic Acid sodium hydrate | 2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]etha |
|---|---|
| Specifications & Purity | Moligand™, ≥97%(HPLC) |
| Biochemical and Physiological Mechanisms | Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular. |
| Storage Temp | Argon charged |
| Shipped In | Normal |
| Grade | Moligand™ |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | sodium;2-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate;hydrate |
|---|---|
| INCHI | InChI=1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1 |
| InChi Key | RDAJAQDLEFHVNR-NEMAEHQESA-M |
| Canonical SMILES | [Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O |
| Isomeric SMILES | C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C.O.[Na+] |
| WGK Germany | 3 |
| Alternate CAS | 145-42-6 |
| Molecular Weight | 537.68 (anhydrous basis) |
| Beilstein | 3901620 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G23131293 | Certificate of Analysis | Apr 09, 2025 | T134625 |
| B2526216 | Certificate of Analysis | Feb 28, 2025 | T134625 |
| B2526217 | Certificate of Analysis | Feb 28, 2025 | T134625 |
| B2526218 | Certificate of Analysis | Feb 28, 2025 | T134625 |
| B2526219 | Certificate of Analysis | Feb 28, 2025 | T134625 |
| K2411381 | Certificate of Analysis | Nov 01, 2024 | T134625 |
| K2411380 | Certificate of Analysis | Nov 01, 2024 | T134625 |
| K2411379 | Certificate of Analysis | Nov 01, 2024 | T134625 |
| K2411378 | Certificate of Analysis | Nov 01, 2024 | T134625 |
| G23131334 | Certificate of Analysis | Jul 24, 2023 | T134625 |
| G23131335 | Certificate of Analysis | Jul 24, 2023 | T134625 |
| G23131360 | Certificate of Analysis | Jul 24, 2023 | T134625 |
| H2430065 | Certificate of Analysis | Jul 24, 2023 | T134625 |
| G23131282 | Certificate of Analysis | Jul 24, 2023 | T134625 |
| B2426195 | Certificate of Analysis | Jul 24, 2023 | T134625 |
| G23131336 | Certificate of Analysis | Jul 24, 2023 | T134625 |
| G23131306 | Certificate of Analysis | Jul 24, 2023 | T134625 |
| G23131240 | Certificate of Analysis | Jul 24, 2023 | T134625 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
Starting at $69.90
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Starting at $9.90
Starting at $78.90
| 1. Zhuo-Wei SHEN, Meng-Yue LUO, Hai-Hong HU, Hui ZHOU, Hui-Di JIANG, Lu-Shan YU, Su ZENG. (2016) Screening and verifying potential NTCP inhibitors from herbal medicinal ingredients using the LLC-PK1 cell model stably expressing human NTCP. Chinese Journal of Natural Medicines, 14 (549). [PMID:27507206] [10.1016/S1875-5364(16)30065-6] |
| 1. Zhuo-Wei SHEN, Meng-Yue LUO, Hai-Hong HU, Hui ZHOU, Hui-Di JIANG, Lu-Shan YU, Su ZENG. (2016) Screening and verifying potential NTCP inhibitors from herbal medicinal ingredients using the LLC-PK1 cell model stably expressing human NTCP. Chinese Journal of Natural Medicines, 14 (549). [PMID:27507206] [10.1016/S1875-5364(16)30065-6] |
