Rolipram (ZK-62711) - 10mM in DMSO, high purity , CAS No.61413-54-5(DMSO), Inhibitor of phosphodiesterase 4A;Inhibitor of phosphodiesterase 4B;Inhibitor of phosphodiesterase 4C;Inhibitor of phosphodiesterase 4D

Item Number
R408046
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SKUSizeAvailabilityPrice Qty
R408046-1ml
1ml
Available within 4-8 weeks(?)
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$173.90

PDE4 Selective Inhibitors

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Basic Description

SynonymsSB 95952 | 4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one
Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological MechanismsThe PDE4 selective inhibitor, Rolipram (ZK-62711, SB 95952), inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of phosphodiesterase 4A;Inhibitor of phosphodiesterase 4B;Inhibitor of phosphodiesterase 4C;Inhibitor of phosphodiesterase 4D
Product Description

Information

ThePDE4selective inhibitor, Rolipram (ZK-62711, SB 95952), inhibited immunopurifiedPDE4BandPDE4Dactivities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent.
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥98%

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Names and Identifiers

Canonical SMILES COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3
Molecular Weight 275.34

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

SolubilitySolubility (25°C) In vitro DMSO: 74 mg/mL (199.79 mM); Ethanol: 3 mg/mL (8.09 mM); Water: Insoluble;

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