Rho-Kinase-IN-1 - 99%, high purity , CAS No.1035094-83-7

Item Number

R647293

Grouped product items
SKU	Size	Availability	Price
R647293-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$166.90
R647293-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
R647293-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$550.90
R647293-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$990.90
R647293-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,650.90
R647293-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,250.90

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Basic Description

Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Rho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor ( K i values of 30.5 and 3.9 nM for ROCK1 and ROCK2 , respectively) extracted from US20090325960A1, compound 1.008.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Rho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor ( K i values of 30.5 and 3.9 nM for ROCK1 and ROCK2 , respectively) extracted from US20090325960A1, compound 1.008 In Vitro Rho-Kinase-IN-1 is a ROCK inhibitor which can be useful for treating diseases or conditions associated with excessive cell proliferation, remodeling, edema and inflammation. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:ROCK1 30.5 nM (Ki) ROCK2 3.9 nM (Ki)

Names and Identifiers

IUPAC Name	N-[1-[(4-methylsulfanylphenyl)methyl]piperidin-3-yl]-1H-indazol-5-amine
INCHI	InChI=1S/C20H24N4S/c1-25-19-7-4-15(5-8-19)13-24-10-2-3-18(14-24)22-17-6-9-20-16(11-17)12-21-23-20/h4-9,11-12,18,22H,2-3,10,13-14H2,1H3,(H,21,23)
InChi Key	DPZSYTMLVCLGRU-UHFFFAOYSA-N
Canonical SMILES	CSC1=CC=C(C=C1)CN2CCCC(C2)NC3=CC4=C(C=C3)NN=C4
Isomeric SMILES	CSC1=CC=C(C=C1)CN2CCCC(C2)NC3=CC4=C(C=C3)NN=C4
PubChem CID	25008330
Molecular Weight	352.50

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Basic Description