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Retinyl acetate - synthetic, crystalline solid or supercooled liquid, high purity , CAS No.127-47-9

1 Citations

from Synthetic

crystalline solid or supercooled liquid

CAS#: 127-47-9
Molecular Weight: 328.49
Beilstein Registry Number: 1915439
EC Number: 204-844-2
PubChem CID: 638034

Item Number

R431692

Grouped product items
SKU	Size	Availability	Price
R431692-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$29.90
R431692-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$89.90
R431692-25g	25g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$269.90
R431692-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$699.90

Basic Description

Synonyms	DTXSID6021240 \| Vitamin A acetate 10 microg/mL in Acetonitrile \| Myvax (VAN) \| NCGC00090756-09 \| Tox21_201423 \| trans-Retinyl acetate \| VitaminAacetate \| BDBM50442911 \| RETINYL ACETATE [USP-RS] \| NCGC00090756-02 \| NCGC00090756-06 \| trans-Vitamin A acetate
Specifications & Purity	from Synthetic, crystalline solid or supercooled liquid
Biochemical and Physiological Mechanisms	Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinoids also exist as retinyl esters such as retinyl propionat
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	from Synthetic
Product Description	Vitamin A usually occurs in food as retinyl esters, which are the pre-formed sources of vitamin A. Retinyl acetate exists as yellow crystals and is insoluble in water. It is soluble in ethanol and oils. Application Retinyl acetate has been used: to study its effects on cochlear development in mice as a component of an internal standard to quantify antioxidants in yolk as an internal standard to determine serum retinol concentration

AI Insight

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] acetate
INCHI	InChI=1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
InChi Key	QGNJRVVDBSJHIZ-QHLGVNSISA-N
Canonical SMILES	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCOC(=O)C)C)C
Isomeric SMILES	CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/COC(=O)C)/C)/C
WGK Germany	2
RTECS	VH6825000
PubChem CID	638034
Molecular Weight	328.49
Beilstein	1915439

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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9 results found

Lot Number	Certificate Type	Date	Item
A2410344	Certificate of Analysis	Dec 28, 2023	R431692
A2410345	Certificate of Analysis	Dec 28, 2023	R431692
A2410346	Certificate of Analysis	Dec 28, 2023	R431692
A2410347	Certificate of Analysis	Dec 28, 2023	R431692
A2410348	Certificate of Analysis	Dec 28, 2023	R431692
A2410349	Certificate of Analysis	Dec 28, 2023	R431692
A2410350	Certificate of Analysis	Dec 28, 2023	R431692
A2410351	Certificate of Analysis	Dec 28, 2023	R431692
A2403056	Certificate of Analysis	Dec 15, 2023	R431692

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H413:May cause long lasting harmful effects to aquatic life H302:Harmful if swallowed
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P301+P312:IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.
WGK Germany	2
RTECS	VH6825000

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Reviews

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Bing Pang, Han Jin, Ning Liao, Junjun Li, Chunmei Jiang, Junling Shi. (2021) Vitamin A supplementation ameliorates ulcerative colitis in gut microbiota–dependent manner. FOOD RESEARCH INTERNATIONAL, 148 (110568). [PMID:34507723] [10.1016/j.foodres.2021.110568]

References

1. Roxana A Radu,Jane Hu,Jennifer Peng,Dean Bok,Nathan L Mata,Gabriel H Travis. (2008-05-14) Retinal pigment epithelium-retinal G protein receptor-opsin mediates light-dependent translocation of all-trans-retinyl esters for synthesis of visual chromophore in retinal pigment epithelial cells.. The Journal of biological chemistry, 283 ((28)): (19730-19738). [PMID:18474598]
2. Peter Coward,Marion Conn,Jie Tang,Fei Xiong,Anthony Menjares,Jeff D Reagan. (2008-10-28) Application of an allosteric model to describe the interactions among retinol binding protein 4, transthyretin, and small molecule retinol binding protein 4 ligands.. Analytical biochemistry, 384 ((2)): (312-320). [PMID:18952041]
3. M M Delgado-Zamarreño,M Bustamante-Rangel,M García-Jiménez,A Sánchez-Pérez,R Carabias-Martínez. (2008-10-31) Off-line coupling of pressurized liquid extraction and LC/ED for the determination of retinyl acetate and tocopherols in infant formulas.. Talanta, 70 ((5)): (1094-1099). [PMID:18970886]
4. Anne L Escaron,Michael H Green,Sherry A Tanumihardjo. (2008-12-02) Plasma turnover of 3,4-didehydroretinol (vitamin A2) increases in vitamin A-deficient rats fed low versus high dietary fat.. Journal of lipid research, 50 ((4)): (694-703). [PMID:19043141]
5. M M Marchenko,I A Shmarakov,M V Pasaĭliuk. (2009-02-21) [Effect of vitamin A provision on antineoplastic resistance in rats].. Voprosy pitaniia, 77 ((6)): (4-8). [PMID:19227855]
6. Akiko Maeda,Tadao Maeda,Marcin Golczak,Steven Chou,Amar Desai,Charles L Hoppel,Shigemi Matsuyama,Krzysztof Palczewski. (2009-03-24) Involvement of all-trans-retinal in acute light-induced retinopathy of mice.. The Journal of biological chemistry, 284 ((22)): (15173-15183). [PMID:19304658]
7. Tadao Maeda,Artur V Cideciyan,Akiko Maeda,Marcin Golczak,Tomas S Aleman,Samuel G Jacobson,Krzysztof Palczewski. (2009-04-03) Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.. Human molecular genetics, 18 ((12)): (2277-2287). [PMID:19339306]
8. Guangwen Tang,Jian Qin,Gregory G Dolnikowski,Robert M Russell,Michael A Grusak. (2009-04-17) Golden Rice is an effective source of vitamin A.. The American journal of clinical nutrition, 89 ((6)): (1776-1783). [PMID:19369372]
9. Mary Ann Asson-Batres,W Bradford Smith,Gale Clark. (2009-05-01) Retinoic acid is present in the postnatal rat olfactory organ and persists in vitamin A--depleted neural tissue.. The Journal of nutrition, 139 ((6)): (1067-1072). [PMID:19403718]
10. Tadao Maeda,Akiko Maeda,Gemma Casadesus,Krzysztof Palczewski,Philippe Margaron. (2009-05-02) Evaluation of 9-cis-retinyl acetate therapy in Rpe65-/- mice.. Investigative ophthalmology & visual science, 50 ((9)): (4368-4378). [PMID:19407008]
11. Ehab I Taha,Saleh A Al-Suwayeh,Md Khalid Anwer. (2009-06-02) Preparation, in vitro and in vivo evaluation of solid-state self-nanoemulsifying drug delivery system (SNEDDS) of vitamin A acetate.. Journal of drug targeting, 17 ((6)): (468-473). [PMID:19480612]
12. Avash J Singh,Vadim Bronshtein,Minesh Khashu,Kyle Lee,James E Potts,James Friel,Philippe Chessex. (2010-03-11) Vitamin A is systemically bioavailable after intratracheal administration with surfactant in an animal model of newborn respiratory distress.. Pediatric research, 67 ((6)): (619-623). [PMID:20216104]
13. Richard A Ejoh,Joseph T Dever,Jordan P Mills,Sherry A Tanumihardjo. (2010-04-24) Small quantities of carotenoid-rich tropical green leafy vegetables indigenous to Africa maintain vitamin A status in Mongolian gerbils ( Meriones unguiculatus).. The British journal of nutrition, 103 ((11)): (1594-1601). [PMID:20412609]
14. Natalia Davydova,Erika Stippler,Ping Jin,Gabriel Giancaspro. (2010-04-30) Development and validation of a dissolution test method for vitamin A in dietary supplement tablets.. Journal of pharmaceutical and biomedical analysis, 53 ((3)): (295-301). [PMID:20427140]
15. Natalia Cernicchiaro,David L Pearl,Scott A McEwen,Henry N Zerby,Francis L Fluharty,Steve C Loerch,Michael D Kauffman,Jaime L Bard,Jeffrey T LeJeune. (2010-05-27) A randomized controlled trial to assess the impact of dietary energy sources, feed supplements, and the presence of super-shedders on the detection of Escherichia coli O157:H7 in feedlot cattle using different diagnostic procedures.. Foodborne pathogens and disease, 7 ((9)): (1071-1081). [PMID:20500082]
16. Emmanuel K Aklamati,Modest Mulenga,Stephen R Dueker,Bruce A Buchholz,Janet M Peerson,Emmanuel Kafwembe,Kenneth H Brown,Marjorie J Haskell. (2010-07-28) Accelerator mass spectrometry can be used to assess vitamin A metabolism quantitatively in boys in a community setting.. The Journal of nutrition, 140 ((9)): (1588-1594). [PMID:20660280]
17. Abad Khan,Muhammad I Khan,Zafar Iqbal,Yasar Shah,Lateef Ahmad,David G Watson. (2010-08-11) An optimized and validated RP-HPLC/UV detection method for simultaneous determination of all-trans-retinol (vitamin A) and alpha-tocopherol (vitamin E) in human serum: comparison of different particulate reversed-phase HPLC columns.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878 ((25)): (2339-2347). [PMID:20696624]
18. Sunatda Arayachukeat,Supason P Wanichwecharungruang,Thapakorn Tree-Udom. (2010-11-26) Retinyl acetate-loaded nanoparticles: dermal penetration and release of the retinyl acetate.. International journal of pharmaceutics, 404 ((1-2)): (281-288). [PMID:21093565]
19. Z Wojnarowska,M Paluch,P Wlodarczyk,L Hawelek,R Wrzalik,J Zioło,M Wygledowska-Kania,B Bergler-Czop,L Brzezinska-Wcislo,P Bujak. (2011-07-07) Nanoscale domains with nematic order in supercooled vitamin-A acetate: molecular dynamics studies.. Physical review. E, Statistical, nonlinear, and soft matter physics, 83 ((5 Pt 1)): (051502-051502). [PMID:21728535]
20. Hui-Jeong Jang,Sang-Hwal Yoon,Hee-Kyung Ryu,Jung-Hun Kim,Chong-Long Wang,Jae-Yean Kim,Deok-Kun Oh,Seon-Won Kim. (2011-08-02) Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system.. Microbial cell factories, 10 (59-59). [PMID:21801353]
21. L Valgimigli,S Gabbanini,E Berlini,E Lucchi,C Beltramini,Y L Bertarelli. (2012-04-21) Lemon (Citrus limon, Burm.f.) essential oil enhances the trans-epidermal release of lipid-(A, E) and water-(B6, C) soluble vitamins from topical emulsions in reconstructed human epidermis.. International journal of cosmetic science, 34 ((4)): (347-356). [PMID:22515469]
22. Pilar Viñas,María Bravo-Bravo,Ignacio López-García,Manuel Hernández-Córdoba. (2013-01-08) Quantification of β-carotene, retinol, retinyl acetate and retinyl palmitate in enriched fruit juices using dispersive liquid-liquid microextraction coupled to liquid chromatography with fluorescence detection and atmospheric pressure chemical ionization-mass spectrometry.. Journal of chromatography. A, 1275 (1-8). [PMID:23290361]
23. Shally Awasthi,Richard Peto,Simon Read,Sarah Clark,Vinod Pande,Donald Bundy. (2013-03-19) Vitamin A supplementation every 6 months with retinol in 1 million pre-school children in north India: DEVTA, a cluster-randomised trial.. Lancet (London, England), 381 ((9876)): (1469-1477). [PMID:23498849]
24. Shally Awasthi,Richard Peto,Simon Read,Susan M Richards,Vinod Pande,Donald Bundy. (2013-03-19) Population deworming every 6 months with albendazole in 1 million pre-school children in North India: DEVTA, a cluster-randomised trial.. Lancet (London, England), 381 ((9876)): (1478-1486). [PMID:23498850]
25. Paul Garner,David Taylor-Robinson,Harshpal Singh Sachdev. (2013-03-19) DEVTA: results from the biggest clinical trial ever.. Lancet (London, England), 381 ((9876)): (1439-1441). [PMID:23498851]
26. Edward C Bell,Mathew John,Rodney J Hughes,Thu Pham. (2013-10-31) Ultra-performance liquid chromatographic determination of tocopherols and retinol in human plasma.. Journal of chromatographic science, 52 ((9)): (1065-1070). [PMID:24170122]
27. Adrienne McMahon,Scott Christiansen,Lynsey Shine,Calvin Loi,Dawn Dowell. (2013-11-29) Simultaneous determination of 13-cis and all-trans vitamin A palmitate (retinyl palmitate), vitamin A acetate (retinyl acetate), and total vitamin E (alpha-tocopherol and DL-alpha-tocopherol acetate) in infant formula and adult nutritionals by normal phase HPLC: first action 2012.10.. Journal of AOAC International, 96 ((5)): (1073-1081). [PMID:24282950]
28. Siwaporn Pinkaew,Rita Wegmuller,Emorn Wasantwisut,Pattanee Winichagoon,Richard F Hurrell,Sherry A Tanumihardjo. (2014-02-07) Triple-fortified rice containing vitamin A reduced marginal vitamin A deficiency and increased vitamin A liver stores in school-aged Thai children.. The Journal of nutrition, 144 ((4)): (519-524). [PMID:24500930]
29. Kara A Bresnahan,Christopher R Davis,Sherry A Tanumihardjo. (2014-04-09) Relative vitamin A values of 9-cis- and 13-cis-β-carotene do not differ when fed at physiological levels during vitamin A depletion in Mongolian gerbils (Meriones unguiculatus).. The British journal of nutrition, 112 ((2)): (162-169). [PMID:24709067]
30. Napaporn Riabroy,Sherry A Tanumihardjo. (2014-06-20) Oral doses of α-retinyl ester track chylomicron uptake and distribution of vitamin A in a male piglet model for newborn infants.. The Journal of nutrition, 144 ((8)): (1188-1195). [PMID:24944285]
31. Kaori Taguchi,Eiichiro Fukusaki,Takeshi Bamba. (2014-09-10) Simultaneous analysis for water- and fat-soluble vitamins by a novel single chromatography technique unifying supercritical fluid chromatography and liquid chromatography.. Journal of chromatography. A, 1362 (270-277). [PMID:25200530]
32. Maja Benković,Siniša Srečec,Igor Špoljarić,Gordan Mršić,Ingrid Bauman. (2014-11-08) Fortification of instant coffee beverages - influence of functional ingredients, packaging material and storage time on physical properties of newly formulated, enriched instant coffee powders.. Journal of the science of food and agriculture, 95 ((13)): (2607-2618). [PMID:25377798]
33. Alexandra C Weaver,M Todd See,Sung Woo Kim. (2014-12-24) Protective effect of two yeast based feed additives on pigs chronically exposed to deoxynivalenol and zearalenone.. Toxins, 6 ((12)): (3336-3353). [PMID:25533517]
34. Ulrike Taschler,Renate Schreiber,Chandramohan Chitraju,Gernot F Grabner,Matthias Romauch,Heimo Wolinski,Guenter Haemmerle,Rolf Breinbauer,Rudolf Zechner,Achim Lass,Robert Zimmermann. (2015-03-04) Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells.. Biochimica et biophysica acta, 1851 ((7)): (937-945). [PMID:25732851]
35. Erina Kitagawa,Tatsuya Yamamoto,Kohei Yamamoto,Tomoyuki Nakagawa,Takashi Hayakawa. (2015-03-18) Accumulation of lipid in rat liver was induced by vitamin B₆ deficiency and was ameliorated by supplemental phosphatidylcholine in the diet.. Bioscience, biotechnology, and biochemistry, 79 ((8)): (1320-1326). [PMID:25775923]
36. Robin D Clugston,Li-Shin Huang,William S Blaner. (2015-05-20) Chronic alcohol consumption has a biphasic effect on hepatic retinoid loss.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29 ((9)): (3654-3667). [PMID:25985802]
37. C K Parr,Y Liu,C M Parsons,H H Stein. (2015-05-29) Effects of high-protein or conventional canola meal on growth performance, organ weights, bone ash, and blood characteristics of weanling pigs.. Journal of animal science, 93 ((5)): (2165-2173). [PMID:26020312]
38. J C González-Vega,C L Walk,H H Stein. (2015-05-29) Effects of microbial phytase on apparent and standardized total tract digestibility of calcium in calcium supplements fed to growing pigs.. Journal of animal science, 93 ((5)): (2255-2264). [PMID:26020322]
39. K L Little,B M Bohrer,T Maison,Y Liu,H H Stein,D D Boler. (2015-05-29) Effects of feeding canola meal from high-protein or conventional varieties of canola seeds on growth performance, carcass characteristics, and cutability of pigs.. Journal of animal science, 93 ((3)): (1284-1297). [PMID:26020905]
40. Daniela Lima,L Filipe C Castro,Inês Coelho,Ricardo Lacerda,Manuel Gesto,Joana Soares,Ana André,Ricardo Capela,Tiago Torres,António Paulo Carvalho,Miguel M Santos. (2015-06-20) Effects of Tributyltin and Other Retinoid Receptor Agonists in Reproductive-Related Endpoints in the Zebrafish (Danio rerio).. Journal of toxicology and environmental health. Part A, 78 ((12)): (747-760). [PMID:26090559]
41. G A Casas,H H Stein. (2015-10-07) Effects of microbial phytase on the apparent and standardized total tract digestibility of phosphorus in rice coproducts fed to growing pigs.. Journal of animal science, 93 ((7)): (3441-3448). [PMID:26440013]
42. Ling Zhang,Xiaoyang Ren,Eckhard Alt,Xiaowen Bai,Shaoyi Huang,Zhengming Xu,Patrick M Lynch,Mary P Moyer,Xian-Feng Wen,Xiangwei Wu. (2010-03-30) Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis.. Nature, 464 ((7291)): (1058-1061). [PMID:20348907]
43. Kajal Babamiri,Reza Nassab. (2010-05-06) Cosmeceuticals: the evidence behind the retinoids.. Aesthetic surgery journal, 30 ((1)): (74-77). [PMID:20442078]
44. Bing Pang, Han Jin, Ning Liao, Junjun Li, Chunmei Jiang, Junling Shi. (2021) Vitamin A supplementation ameliorates ulcerative colitis in gut microbiota–dependent manner. FOOD RESEARCH INTERNATIONAL, 148 (110568). [PMID:34507723] [10.1016/j.foodres.2021.110568]

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