Determine the necessary mass, volume, or concentration for preparing a solution.
Basic Description
| Synonyms | PYRIDOXAL HYDROCHLORIDE | 65-22-5 | Pyridoxal HCl | 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride | 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine hydrochloride | MFCD00012809 | 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde, hydro |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Pyridoxal hydrochloride interacts with cysteine of cathepsins and inhibits their activity. It elicits protective function in cornu Ammonis (CA) 1 neurons during ischemia.Pyridoxal hydrochloride is an endogenous metabolite. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description |
Pyridoxal hydrochloride is used in labeling of amino acids for their detection. It finds application in neurotransmitters, sphingolipids and aminolevulinic acid. It is also used as a nutritional agent. It is also applied in research studies like biochemical, drugs and in media supplements.
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AI Insight
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde;hydrochloride |
|---|---|
| INCHI | InChI=1S/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H |
| InChi Key | FCHXJFJNDJXENQ-UHFFFAOYSA-N |
| Canonical SMILES | CC1=NC=C(C(=C1O)C=O)CO.Cl |
| Isomeric SMILES | CC1=NC=C(C(=C1O)C=O)CO.Cl |
| WGK Germany | 2 |
| RTECS | UV1225000 |
| PubChem CID | 6171 |
| Molecular Weight | 203.62 |
| Beilstein | 3656994 |
| Reaxy-Rn | 3656994 |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 2 |
| RTECS | UV1225000 |
| Reaxy-Rn | 3656994 |
| Merck Index | 7978 |
Related Documents
Reviews
Customer Reviews
Citations of This Product
| 1. Deng Hao-Hua, Yang Hui-Jing, Huang Kai-Yuan, Zheng Yi-Jing, Xu Ying-Ying, Peng Hua-Ping, Liu Yin-Huan, Chen Wei, Hong Guo-Lin. (2022) Antenna effect of pyridoxal phosphate on the fluorescence of mitoxantrone-silicon nanoparticles and its application in alkaline phosphatase assay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (17): (4877-4884). [PMID:35576012] [10.1007/s00216-022-04110-7] |
| 2. Hao-Hua Deng, Kai-Yuan Huang, Quan-Hui Fang, Ya-Ping Lv, Shao-Bin He, Hua-Ping Peng, Xing-Hua Xia, Wei Chen. (2020) Schiff base and Lewis acid-base interaction-regulated aggregation/dispersion of gold nanoparticles for colorimetric recognition of rare-earth Sc3+ ions. SENSORS AND ACTUATORS B-CHEMICAL, 311 (127925). [PMID:] [10.1016/j.snb.2020.127925] |
| 3. Q. Huang, Y. T. Chen, Y. W. Ren, Z. Y. Wang, Y. X. Zhu, Y. Zhang. (2018) A rapid and naked-eye visible rhodamine 6G-based chemosensor for sensitive detection of copper(II) ions in aqueous solution. Analytical Methods, 10 (47): (5731-5737). [PMID:] [10.1039/C8AY02019A] |
| 4. Su Yao, Gongke Li, Yanqing Liu, Shoulian Wei, Hongwu Wang, Xiqing Huang, Zetao Luo. (2018) Electrochemical detection of pyridoxal using a sonoelectrochemical prepared highly-oxidized carbon nanosheets modified electrode. SENSORS AND ACTUATORS B-CHEMICAL, 274 (324). [PMID:] [10.1016/j.snb.2018.07.106] |
| 5. Qi Huang, Qingyou Zhang, Enze Wang, Yanmei Zhou, Han Qiao, Lanfang Pang, Fang Yu. (2016) A new “off–on” fluorescent probe for Al3+ in aqueous solution based on rhodamine B and its application to bioimaging. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 152 (70). [PMID:26196932] [10.1016/j.saa.2015.07.062] |
References
| 1. Deng Hao-Hua, Yang Hui-Jing, Huang Kai-Yuan, Zheng Yi-Jing, Xu Ying-Ying, Peng Hua-Ping, Liu Yin-Huan, Chen Wei, Hong Guo-Lin. (2022) Antenna effect of pyridoxal phosphate on the fluorescence of mitoxantrone-silicon nanoparticles and its application in alkaline phosphatase assay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (17): (4877-4884). [PMID:35576012] [10.1007/s00216-022-04110-7] |
| 2. Hao-Hua Deng, Kai-Yuan Huang, Quan-Hui Fang, Ya-Ping Lv, Shao-Bin He, Hua-Ping Peng, Xing-Hua Xia, Wei Chen. (2020) Schiff base and Lewis acid-base interaction-regulated aggregation/dispersion of gold nanoparticles for colorimetric recognition of rare-earth Sc3+ ions. SENSORS AND ACTUATORS B-CHEMICAL, 311 (127925). [PMID:] [10.1016/j.snb.2020.127925] |
| 3. Q. Huang, Y. T. Chen, Y. W. Ren, Z. Y. Wang, Y. X. Zhu, Y. Zhang. (2018) A rapid and naked-eye visible rhodamine 6G-based chemosensor for sensitive detection of copper(II) ions in aqueous solution. Analytical Methods, 10 (47): (5731-5737). [PMID:] [10.1039/C8AY02019A] |
| 4. Su Yao, Gongke Li, Yanqing Liu, Shoulian Wei, Hongwu Wang, Xiqing Huang, Zetao Luo. (2018) Electrochemical detection of pyridoxal using a sonoelectrochemical prepared highly-oxidized carbon nanosheets modified electrode. SENSORS AND ACTUATORS B-CHEMICAL, 274 (324). [PMID:] [10.1016/j.snb.2018.07.106] |
| 5. Qi Huang, Qingyou Zhang, Enze Wang, Yanmei Zhou, Han Qiao, Lanfang Pang, Fang Yu. (2016) A new “off–on” fluorescent probe for Al3+ in aqueous solution based on rhodamine B and its application to bioimaging. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 152 (70). [PMID:26196932] [10.1016/j.saa.2015.07.062] |