| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| P111170-1g | 1g | 3 | $20.90 | |
| P111170-5g | 5g | 2 | $45.90 | |
| P111170-25g | 25g | 2 | $134.90 | |
| P111170-100g | 100g | 2 | $485.90 |
| Synonyms | 3-Hydroxy-5-hydroxymethyl-2-methylisonicotinaldehyde hydrochloride | P0559 | 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride | 3-Hydroxy-5-(hydroxymethyl)-2-methyl-isonicotinaldehyde hydrochloride | 3-Hydroxy-5-(hydroxymethyl)-2-methy |
|---|---|
| Specifications & Purity | ≥99% |
| Biochemical and Physiological Mechanisms | Pyridoxal hydrochloride interacts with cysteine of cathepsins and inhibits their activity. It elicits protective function in cornu Ammonis (CA) 1 neurons during ischemia.Pyridoxal hydrochloride is an endogenous metabolite. |
| Storage Temp | Protected from light,Store at -20°C,Argon charged |
| Shipped In | Ice chest + Ice pads |
| Product Description |
Pyridoxal hydrochloride is used in labeling of amino acids for their detection. It finds application in neurotransmitters, sphingolipids and aminolevulinic acid. It is also used as a nutritional agent. It is also applied in research studies like biochemical, drugs and in media supplements.
|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde;hydrochloride |
|---|---|
| INCHI | InChI=1S/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H |
| InChi Key | FCHXJFJNDJXENQ-UHFFFAOYSA-N |
| Canonical SMILES | CC1=NC=C(C(=C1O)C=O)CO.Cl |
| Isomeric SMILES | CC1=NC=C(C(=C1O)C=O)CO.Cl |
| WGK Germany | 2 |
| RTECS | UV1225000 |
| PubChem CID | 6171 |
| Molecular Weight | 203.62 |
| Beilstein | 3656994 |
| Reaxy-Rn | 3656994 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 I2212224 | Certificate of Analysis | Jun 19, 2024 | P111170 |
| I2212225 | Certificate of Analysis | Jun 19, 2024 | P111170 |
| I2212226 | Certificate of Analysis | Jun 19, 2024 | P111170 |
| I2212227 | Certificate of Analysis | Jun 12, 2024 | P111170 |
| B2419387 | Certificate of Analysis | Jan 30, 2024 | P111170 |
| B2419389 | Certificate of Analysis | Jan 30, 2024 | P111170 |
| B2419390 | Certificate of Analysis | Jan 30, 2024 | P111170 |
| I2321834 | Certificate of Analysis | Sep 14, 2023 | P111170 |
| I2321889 | Certificate of Analysis | Sep 14, 2023 | P111170 |
| I2321896 | Certificate of Analysis | Sep 14, 2023 | P111170 |
| K2127658 | Certificate of Analysis | Sep 11, 2023 | P111170 |
| K2127659 | Certificate of Analysis | Sep 11, 2023 | P111170 |
| K2127660 | Certificate of Analysis | Sep 11, 2023 | P111170 |
| B2120145 | Certificate of Analysis | Nov 14, 2022 | P111170 |
| B2120144 | Certificate of Analysis | Nov 14, 2022 | P111170 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 2 |
| RTECS | UV1225000 |
| Reaxy-Rn | 3656994 |
| Merck Index | 7978 |
| 1. Deng Hao-Hua, Yang Hui-Jing, Huang Kai-Yuan, Zheng Yi-Jing, Xu Ying-Ying, Peng Hua-Ping, Liu Yin-Huan, Chen Wei, Hong Guo-Lin. (2022) Antenna effect of pyridoxal phosphate on the fluorescence of mitoxantrone-silicon nanoparticles and its application in alkaline phosphatase assay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (17): (4877-4884). [PMID:35576012] [10.1007/s00216-022-04110-7] |
| 2. Hao-Hua Deng, Kai-Yuan Huang, Quan-Hui Fang, Ya-Ping Lv, Shao-Bin He, Hua-Ping Peng, Xing-Hua Xia, Wei Chen. (2020) Schiff base and Lewis acid-base interaction-regulated aggregation/dispersion of gold nanoparticles for colorimetric recognition of rare-earth Sc3+ ions. SENSORS AND ACTUATORS B-CHEMICAL, 311 (127925). [PMID:] [10.1016/j.snb.2020.127925] |
| 3. Q. Huang, Y. T. Chen, Y. W. Ren, Z. Y. Wang, Y. X. Zhu, Y. Zhang. (2018) A rapid and naked-eye visible rhodamine 6G-based chemosensor for sensitive detection of copper(II) ions in aqueous solution. Analytical Methods, 10 (47): (5731-5737). [PMID:] [10.1039/C8AY02019A] |
| 4. Su Yao, Gongke Li, Yanqing Liu, Shoulian Wei, Hongwu Wang, Xiqing Huang, Zetao Luo. (2018) Electrochemical detection of pyridoxal using a sonoelectrochemical prepared highly-oxidized carbon nanosheets modified electrode. SENSORS AND ACTUATORS B-CHEMICAL, 274 (324). [PMID:] [10.1016/j.snb.2018.07.106] |
| 5. Qi Huang, Qingyou Zhang, Enze Wang, Yanmei Zhou, Han Qiao, Lanfang Pang, Fang Yu. (2016) A new “off–on” fluorescent probe for Al3+ in aqueous solution based on rhodamine B and its application to bioimaging. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 152 (70). [PMID:26196932] [10.1016/j.saa.2015.07.062] |
| 1. Masoud Vedadi,Frank H Niesen,Abdellah Allali-Hassani,Oleg Y Fedorov,Patrick J Finerty,Gregory A Wasney,Ron Yeung,Cheryl Arrowsmith,Linda J Ball,Helena Berglund,Raymond Hui,Brian D Marsden,Pär Nordlund,Michael Sundstrom,Johan Weigelt,Aled M Edwards. (2006-10-13) Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.. Proceedings of the National Academy of Sciences of the United States of America, 103 ((43)): (15835-15840). [PMID:17035505] |
| 2. Eric Nurit,Bernard Lyan,Agnès Piquet,Gérard Branlard,Estelle Pujos-Guillot. (2015-02-24) Development of a LC-MS/MS method for the simultaneous screening of seven water-soluble vitamins in processing semi-coarse wheat flour products.. Analytical and bioanalytical chemistry, 407 ((12)): (3471-3479). [PMID:25701425] |
| 3. Lucia Carrano,Monica Abbondi,Paola Turconi,Gianpaolo Candiani,Flavia Marinelli. (2015-09-09) A Novel Microbisporicin Producer Identified by Early Dereplication during Lantibiotic Screening.. BioMed research international, 2015 (419383-419383). [PMID:26346738] |
| 4. Bachmann, et al.. (2021) Development of a LC-MS/MS method using stable isotope dilution for the quantification of individual B6 vitamers in fruits, vegetables, and cereals.. Analytical and Bioanalytical Chemistry, 412 (7237-7252). [PMID:32797304] |
| 5. Ashish A Kawale,Björn M Burmann. (2021-11-12) Characterization of backbone dynamics using solution NMR spectroscopy to discern the functional plasticity of structurally analogous proteins.. STAR protocols, 2 ((4)): (100919-100919). [PMID:34761231] |
| 6. Toshio Iwasaki,Rimma I Samoilova,Asako Kounosu,Daijiro Ohmori,Sergei A Dikanov. (2009-09-10) Continuous-wave and pulsed EPR characterization of the [2Fe-2S](Cys)3(His)1 cluster in rat MitoNEET.. Journal of the American Chemical Society, 131 ((38)): (13659-13667). [PMID:19736979] |
| 7. Deng Hao-Hua, Yang Hui-Jing, Huang Kai-Yuan, Zheng Yi-Jing, Xu Ying-Ying, Peng Hua-Ping, Liu Yin-Huan, Chen Wei, Hong Guo-Lin. (2022) Antenna effect of pyridoxal phosphate on the fluorescence of mitoxantrone-silicon nanoparticles and its application in alkaline phosphatase assay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (17): (4877-4884). [PMID:35576012] [10.1007/s00216-022-04110-7] |
| 8. Hao-Hua Deng, Kai-Yuan Huang, Quan-Hui Fang, Ya-Ping Lv, Shao-Bin He, Hua-Ping Peng, Xing-Hua Xia, Wei Chen. (2020) Schiff base and Lewis acid-base interaction-regulated aggregation/dispersion of gold nanoparticles for colorimetric recognition of rare-earth Sc3+ ions. SENSORS AND ACTUATORS B-CHEMICAL, 311 (127925). [PMID:] [10.1016/j.snb.2020.127925] |
| 9. Q. Huang, Y. T. Chen, Y. W. Ren, Z. Y. Wang, Y. X. Zhu, Y. Zhang. (2018) A rapid and naked-eye visible rhodamine 6G-based chemosensor for sensitive detection of copper(II) ions in aqueous solution. Analytical Methods, 10 (47): (5731-5737). [PMID:] [10.1039/C8AY02019A] |
| 10. Su Yao, Gongke Li, Yanqing Liu, Shoulian Wei, Hongwu Wang, Xiqing Huang, Zetao Luo. (2018) Electrochemical detection of pyridoxal using a sonoelectrochemical prepared highly-oxidized carbon nanosheets modified electrode. SENSORS AND ACTUATORS B-CHEMICAL, 274 (324). [PMID:] [10.1016/j.snb.2018.07.106] |
| 11. Qi Huang, Qingyou Zhang, Enze Wang, Yanmei Zhou, Han Qiao, Lanfang Pang, Fang Yu. (2016) A new “off–on” fluorescent probe for Al3+ in aqueous solution based on rhodamine B and its application to bioimaging. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 152 (70). [PMID:26196932] [10.1016/j.saa.2015.07.062] |
