| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| P433000-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $379.90 |
| Synonyms | 3'-amino-3'-deoxy-n(6),n(6)-dimethyladenosine | 0Q580U88V8 | Aminonucleoside | DTXSID7037264 | NSC 3056NSC 3056 | EINECS 200-388-3 | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL | AT25062 | Stylomycin ami |
|---|---|
| Specifications & Purity | 10 mg/mL in water |
| Biochemical and Physiological Mechanisms | Puromycin aminonucleoside is an aminonucleoside derivative of the known antibiotic puromycin. Puromycin aminonucleoside has been used in nephrology research, studying focal and segmental glomerulosclerosis, and in the induction of nephrosis in rats. Rats |
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | (2R,3R,4S,5S)-4-amino-2-[6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)oxolan-3-ol |
|---|---|
| INCHI | InChI=1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7-,9-,12-/m1/s1 |
| InChi Key | RYSMHWILUNYBFW-GRIPGOBMSA-N |
| Canonical SMILES | CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)N)O |
| Isomeric SMILES | CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)N)O |
| WGK Germany | 3 |
| PubChem CID | 6020 |
| Molecular Weight | 294.31 |
| Beilstein | 93902 |
| Pictogram(s) | GHS08 |
|---|---|
| Signal | Warning |
| Hazard Statements | H373:Causes damage to organs through prolonged or repeated exposure |
| Precautionary Statements | P501:Dispose of contents/container to ... P260:Do not breathe dust/fume/gas/mist/vapors/spray. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
Starting at $241.90
Starting at $48.90
| 1. Agnes B Fogo. (2003-04-22) Animal models of FSGS: lessons for pathogenesis and treatment.. Seminars in nephrology, 23 ((2)): (161-171). [PMID:12704576] |
| 2. Zhenmin Ni,Nosratola D Vaziri. (2003-07-11) Downregulation of nitric oxide synthase in nephrotic syndrome: role of proteinuria.. Biochimica et biophysica acta, 1638 ((2)): (129-137). [PMID:12853118] |
| 3. Alicia A McDonough,Daniel Biemesderfer. (2003-08-16) Does membrane trafficking play a role in regulating the sodium/hydrogen exchanger isoform 3 in the proximal tubule?. Current opinion in nephrology and hypertension, 12 ((5)): (533-541). [PMID:12920402] |
| 4. Khalil Udwan,Gaëlle Brideau,Marc Fila,Aurélie Edwards,Bruno Vogt,Alain Doucet. (2016-04-02) Oxidative Stress and Nuclear Factor κB (NF-κB) Increase Peritoneal Filtration and Contribute to Ascites Formation in Nephrotic Syndrome.. The Journal of biological chemistry, 291 ((21)): (11105-11113). [PMID:27033704] |
| 5. Jenny Sörensson,Anna Björnson,Maria Ohlson,Barbara J Ballermann,Börje Haraldsson. (2002-10-22) Synthesis of sulfated proteoglycans by bovine glomerular endothelial cells in culture.. American journal of physiology. Renal physiology, 284 ((2)): (F373-F380). [PMID:12388398] |
| 6. Marta Bermejo-Jambrina,Michael Blatzer,Paula Jauregui-Onieva,Teodor E Yordanov,Paul Hörtnagl,Taras Valovka,Lukas A Huber,Doris Wilflingseder,Wilfried Posch. (2020-09-15) CR4 Signaling Contributes to a DC-Driven Enhanced Immune Response Against Complement-Opsonized HIV-1.. Frontiers in immunology, 11 (2010-2010). [PMID:32922405] |
