programmed cell death 1 ligand 1, programmed cell death 1 (CD279), CAS No.rp174805, programmed cell death 1 (CD279)

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    Item Number
    rp174805
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    rp174805-500μg
    500μg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,334.90
    rp174805-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $2,334.90

    Basic Description

    Product Nameprogrammed cell death 1 ligand 1, programmed cell death 1 (CD279), CAS No.rp174805
    GradeMoligand™
    Specifications & PurityMoligand™
    Mechanism of actionprogrammed cell death 1 (CD279)

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    CASrp174805

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    References

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    2. Greaves P, Gribben JG.  (2013)  The role of B7 family molecules in hematologic malignancy..  Blood,  121  (5): (734-44).  [PMID:23223433] [10.1021/op500134e]
    3. Tang PA, Heng DY.  (2013)  Programmed death 1 pathway inhibition in metastatic renal cell cancer and prostate cancer..  Curr Oncol Rep,  15  (2): (98-104).  [PMID:23263823] [10.1021/op500134e]
    4. Lu J, Lee-Gabel L, Nadeau MC, Ferencz TM, Soefje SA.  (2015)  Clinical evaluation of compounds targeting PD-1/PD-L1 pathway for cancer immunotherapy..  J Oncol Pharm Pract,  21  (6): (451-67).  [PMID:24917416] [10.1021/op500134e]
    5. Johnson DB, Rioth MJ, Horn L.  (2014)  Immune checkpoint inhibitors in NSCLC..  Curr Treat Options Oncol,  15  (4): (658-69).  [PMID:25096781] [10.1021/op500134e]
    6. Sasikumar PG, Ramachandra M.  (2017)  Small-molecule antagonists of the immune checkpoint pathways: concept to clinic..  Future Med Chem,  (12): (1305-1308).  [PMID:28771036] [10.1021/op500134e]
    7. Miao X, Xu R, Fan B, Chen J, Li X, Mao W, Hua S, Li B.  (2018)  PD-L1 reverses depigmentation in Pmel-1 vitiligo mice by increasing the abundance of Tregs in the skin..  Sci Rep,  (1): (1605).  [PMID:29371688] [10.1021/op500134e]
    8. Guzik K, Zak KM, Grudnik P, Magiera K, Musielak B, Törner R, Skalniak L, Dömling A, Dubin G, Holak TA.  (2017)  Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1..  J Med Chem,  60  (13): (5857-5867).  [PMID:28613862] [10.1021/op500134e]

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