| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| P425090-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $47.90 |
Sodium channel blocker. Specific DNA methyltransferase 1 inhibitor.
| Synonyms | procainamide hydrochloride | 614-39-1 | Procainamide Hcl | Pronestyl | Procapan | Procanbid | Procan | Procan SR | 4-amino-N-[2-(diethylamino)ethyl]benzamide hydrochloride | Pronestyl-Sr | Procainhydrochlorid | Procainii chloridum | Promide hydrochloride | Amidoprocaine | Cardiorytm |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Sodium channel blocker. Specific DNA methyltransferase 1 inhibitor (K i = 7.2 μM). Antiarrhythmic in vivo . Limited ability to cross the blood-brain barrier. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Action Type | BLOCKER |
| Mechanism of action | Sodium channel alpha subunit blocker |
| Product Description | Product Application: Procainamide hydrochloride (PAH) is suitable to investigate its binding behavior with human serum albumin and bovine serum albumin by fluorescence quenching study to understand the pharmacokinetic and pharmacodynamic mechanisms of PAH. |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | 4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride |
|---|---|
| INCHI | InChI=1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H |
| InChi Key | ABTXGJFUQRCPNH-UHFFFAOYSA-N |
| Canonical SMILES | CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl |
| Isomeric SMILES | CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl |
| RTECS | CV2295000 |
| PubChem CID | 66068 |
| Molecular Weight | 271.79 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| RTECS | CV2295000 |
