Polyinosinic–polycytidylic acid sodium salt - 99% (less than 1% free nucleotides, TLC), high purity , CAS No.42424-50-0

Item Number

P170294

Grouped product items
SKU	Size	Availability	Price	Qty
P170294-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$79.90
P170294-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$253.90

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Basic Description

Specifications & Purity	≥99%(TLC), less than 1% free nucleotides
Biochemical and Physiological Mechanisms	Transfection of Poly (I: C) into NIT-1 cells has been used for intracellular dsRNA induction β A model of cell apoptosis. 18 hours after transfection, 45% of cells experienced apoptosis, and their NF kB, p50/p65 nuclear translocation, caspase 3 and 8 clea
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Note	Double-stranded homopolymer.The product requires ionic strength to maintain the double-strand structure. To prevent denaturation, reconstitute in solutions with physiological salt concentrations (e.g., saline solution). Reconstitution may require heating (50 °C) and cooling to achieve re-annealing.

Names and Identifiers

INCHI	InChI=1S/C10H13N4O8P.C9H14N3O8P.Na/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);/t4-,6-,7-,10-;4-,6-,7-,8-;/m11./s1
InChi Key	GETQKWBYQAUFQM-VRQAYDGLSA-N
Canonical SMILES	C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O.[Na]
PubChem CID	137229713

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Basic Description