Polyinosinic-polycytidylic acid potassium salt - 99% (less than 1% free nucleotides, TLC)，with buffer salts, high purity , CAS No.31852-29-6

Item Number

P169534

Grouped product items
SKU	Size	Availability	Price	Qty
P169534-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$101.90
P169534-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$405.90

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Basic Description

Synonyms	Poly (I:C), Poly(I) · Poly(C)
Specifications & Purity	≥99%(TLC), less than 1% free nucleotides,with buffer salts
Biochemical and Physiological Mechanisms	Transfection of Poly (I:C) into NIT-1 cells has been used as a model of intracellular dsRNA-induced β cell apoptosis. Eighteen hours post transfection, 45% of the cells were apoptotic with an increase in NF-kB, p50/p65 nuclear translocation, and cleavage
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Product Description： TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic–polycytidylic acid (Poly(I) • Poly(C)) is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.

Names and Identifiers

INCHI	InChI=1S/C10H13N4O8P.C9H14N3O8P.K/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);/t4-,6-,7-,10-;4-,6-,7-,8-;/m11./s1
InChi Key	KHPUABRWHJGXNJ-VRQAYDGLSA-N
Canonical SMILES	C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O.[K]
PubChem CID	137031716

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Lot Number	Certificate Type	Date	Item
J2106046	Certificate of Analysis	Jul 03, 2024	P169534

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Basic Description