NVP DPP 728 - ≥98%, high purity , CAS No.247016-69-9

Item Number

N274739

• Synonyms: NVP-DPP728 | NVP-DPP-728 | NVP-728 | 6-(2-((2-((2S)-2-Cyanopyrrolidin-1-yl)-2-oxo-ethyl)amino)ethylamino)pyridine-3-carbonitrile
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: Potent, selective, reversible dipeptidyl peptidase-IV (DPP-IV) inhibitor (K i = 11 nM). Antidiabetic agent in vivo .
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

NVP-DPP728 is a potent, reversible, nitrile-dependent inhibitor of dipeptidyl peptidase IV (DPP-IV). NVP-DPP728 can inhibit the amide lysozyme activity of human DPP-IV with Ki of 11 nM. NVP-DPP728 inhibits the degradation of glukagon-like peptide-1 (GLP-1), thereby enhancing the release of insulin to glucose intake. NVP-DPP728 can be used in diabetes research