Noradrenaline bitartrate monohydrate - ≥98%(HPLC),USP, high purity , CAS No.108341-18-0

Item Number
N107258
Grouped product items
SKUSizeAvailabilityPrice Qty
N107258-200mg
200mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$60.90
N107258-250mg
250mg
4
$65.90
N107258-1g
1g
1
$216.90
N107258-5g
5g
2
$640.90
N107258-25g
25g
2
$2,884.90

Endogenous α adrenoceptor agonist

Basic Description

SynonymsNoradrenaline (as tartrate) | (-)-alpha-(Aminomethyl)-3,4-dihydroxybenzyl alcohol tartrate (1:1) (salt) monohydrate | Norepinephrine (Bitartrate) | 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)-,(2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt), monohydr
Specifications & PurityPharmPure™, USP, ≥98%(HPLC)
Biochemical and Physiological MechanismsL-Noradrenaline Bitartrate Monohydrate is a demethylated precursor of epinephrine (adrenaline). It is a sympathomimetic hormone produced by the adrenal gland.Autonomic nervous system neurotransmitter released by sympathetic nerve terminals.
Storage TempStore at 2-8°C
Shipped InWet ice
GradePharmPure™, USP
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator.
A demethylated precursor of epinephrine.

AI Insight

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid504762378
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504762378
IUPAC Name 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol;(2R,3R)-2,3-dihydroxybutanedioic acid;hydrate
INCHI InChI=1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1
InChi Key LNBCGLZYLJMGKP-LUDZCAPTSA-N
Canonical SMILES C1=CC(=C(C=C1C(CN)O)O)O.C(C(C(=O)O)O)(C(=O)O)O.O
Isomeric SMILES C1=CC(=C(C=C1[C@H](CN)O)O)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O.O
WGK Germany 3
RTECS DN6750000
Alternate CAS 51-40-1
PubChem CID 3047796
Molecular Weight 337.28
Beilstein 4078502

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
I1708040Certificate of AnalysisApr 09, 2025 N107258
A2509232Certificate of AnalysisApr 12, 2024 N107258
J2312161Certificate of AnalysisOct 19, 2023 N107258
J2312519Certificate of AnalysisOct 19, 2023 N107258
F2305664Certificate of AnalysisApr 27, 2023 N107258
F2305665Certificate of AnalysisApr 27, 2023 N107258
F2305667Certificate of AnalysisApr 27, 2023 N107258
F2305673Certificate of AnalysisApr 27, 2023 N107258
F2305674Certificate of AnalysisApr 27, 2023 N107258
D2324765Certificate of AnalysisMar 23, 2023 N107258
D2324794Certificate of AnalysisMar 23, 2023 N107258

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Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

WGK Germany 3
RTECS DN6750000

Related Documents

Reviews

Customer Reviews

Citations of This Product

1. Yingying Lei, Khaista Rahman, Xiaojian Cao, Bing Yang, Wei Zhou, Aikebaier Reheman, Luxia Cai, Yifan Wang, Rohit Tyagi, Zhe Wang, Xi Chen, Gang Cao.  (2023)  Epinephrine Stimulates Mycobacterium tuberculosis Growth and Biofilm Formation.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (24): (17370).  [PMID:38139199] [10.3390/ijms242417370]
2. Haiying Shen, Lianhua Dong, Yunhua Gao, Xia Wang, Xinhua Dai.  (2023)  Integrated Microwell Array-Based Microfluidic Chip with a Hand-Held Smartphone-Controlled Device for Nucleic Acid Detection.  ANALYTICAL CHEMISTRY,  95  (41): (15394–15399).  [PMID:37787984] [10.1021/acs.analchem.3c03525]
3. Yong Liu, Mingzhu Yang, Juanjuan Li, Wei Zhang, Xingyu Jiang.  (2019)  Plasma Treatment Conversion of Phenolic Compounds into Fluorescent Organic Nanoparticles for Cell Imaging.  ANALYTICAL CHEMISTRY,  91  (10): (6754–6760).  [PMID:31006238] [10.1021/acs.analchem.9b00837]
4. Xia Zhou, Miao Qin, Jun Zhu, Cong Wang, Guang Zhu, Hongyan Wang, Liangbao Yang.  (2018)  Rapid and sensitive surface-enhanced resonance Raman spectroscopy detection for norepinephrine in biofluids.  JOURNAL OF RAMAN SPECTROSCOPY,  50  (3): (314-321).  [PMID:] [10.1002/jrs.5519]
5. Xiaomin Cao, Miao Qin, Pan Li, Binbin Zhou, Xianghu Tang, Meihong Ge, Liangbao Yang, Jinhuai Liu.  (2018)  Probing catecholamine neurotransmitters based on iron-coordination surface-enhanced resonance Raman spectroscopy label.  SENSORS AND ACTUATORS B-CHEMICAL,  268  (350).  [PMID:] [10.1016/j.snb.2018.04.117]
6. Haiying Shen, Feng Qu, Yong Xia, Xingyu Jiang.  (2018)  Straightforward and Ultrastable Surface Modification of Microfluidic Chips with Norepinephrine Bitartrate Improves Performance in Immunoassays.  ANALYTICAL CHEMISTRY,  90  (6): (3697–3702).  [PMID:29478312] [10.1021/acs.analchem.7b05186]

References

1. Yang B et al..  (2021)  Locus coeruleus anchors a trisynaptic circuit controlling fear-induced suppression of feeding..  Neuron,  109  (5): (823-838.e6).  [PMID:33476548]
2. Gao XJ et al..  (2020)  Multi-in-One: Multiple-proteases, One-hour-shot Strategy for Fast and High-coverage Phosphoproteomic Investigation..  Anal Chem,      [PMID:32479063]
3. Honda K et al..  (2021)  On-tissue polysulfide visualization by surface-enhanced Raman spectroscopy benefits patients with ovarian cancer to predict post-operative chemosensitivity..  Redox Biol,  41  (101926).  [PMID:33752108]
4. Rajalingam D et al..  (2021)  Workplace bullying increases the risk of anxiety through a stress-induced ß2-adrenergic receptor mechanism: a multisource study employing an animal model, cell culture experiments and human data..  Int Arch Occup Environ Health,  94  (8): (1905-1915).  [PMID:34076732]
5. Yingying Lei, Khaista Rahman, Xiaojian Cao, Bing Yang, Wei Zhou, Aikebaier Reheman, Luxia Cai, Yifan Wang, Rohit Tyagi, Zhe Wang, Xi Chen, Gang Cao.  (2023)  Epinephrine Stimulates Mycobacterium tuberculosis Growth and Biofilm Formation.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (24): (17370).  [PMID:38139199] [10.3390/ijms242417370]
6. Haiying Shen, Lianhua Dong, Yunhua Gao, Xia Wang, Xinhua Dai.  (2023)  Integrated Microwell Array-Based Microfluidic Chip with a Hand-Held Smartphone-Controlled Device for Nucleic Acid Detection.  ANALYTICAL CHEMISTRY,  95  (41): (15394–15399).  [PMID:37787984] [10.1021/acs.analchem.3c03525]
7. Yong Liu, Mingzhu Yang, Juanjuan Li, Wei Zhang, Xingyu Jiang.  (2019)  Plasma Treatment Conversion of Phenolic Compounds into Fluorescent Organic Nanoparticles for Cell Imaging.  ANALYTICAL CHEMISTRY,  91  (10): (6754–6760).  [PMID:31006238] [10.1021/acs.analchem.9b00837]
8. Xia Zhou, Miao Qin, Jun Zhu, Cong Wang, Guang Zhu, Hongyan Wang, Liangbao Yang.  (2018)  Rapid and sensitive surface-enhanced resonance Raman spectroscopy detection for norepinephrine in biofluids.  JOURNAL OF RAMAN SPECTROSCOPY,  50  (3): (314-321).  [PMID:] [10.1002/jrs.5519]
9. Xiaomin Cao, Miao Qin, Pan Li, Binbin Zhou, Xianghu Tang, Meihong Ge, Liangbao Yang, Jinhuai Liu.  (2018)  Probing catecholamine neurotransmitters based on iron-coordination surface-enhanced resonance Raman spectroscopy label.  SENSORS AND ACTUATORS B-CHEMICAL,  268  (350).  [PMID:] [10.1016/j.snb.2018.04.117]
10. Haiying Shen, Feng Qu, Yong Xia, Xingyu Jiang.  (2018)  Straightforward and Ultrastable Surface Modification of Microfluidic Chips with Norepinephrine Bitartrate Improves Performance in Immunoassays.  ANALYTICAL CHEMISTRY,  90  (6): (3697–3702).  [PMID:29478312] [10.1021/acs.analchem.7b05186]

Solution Calculators