NNC 55-0396 dihydrochloride - ≥99%, high purity , CAS No.357400-13-6

  • ≥99%
Item Number
N274718
Grouped product items
SKUSizeAvailabilityPrice Qty
N274718-5mg
5mg
2
$157.90
N274718-10mg
10mg
2
$256.90
N274718-25mg
25mg
2
$578.90
N274718-50mg
50mg
2
$899.90
N274718-100mg
100mg
2
$1,444.90

Highly selective T-type Ca 2+ channel blocker

Basic Description

SynonymsNNC 55-0396 dihydrochloride | AKOS024457020 | Cyclopropanecarboxylic acid, (1S,2S)-2-(2-((3-(1H-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, dihydrochloride | HY-50722 | rac-(1R,2R)-2-(2-(
Specifications & Purity≥99%
Biochemical and Physiological MechanismsHighly selective T-type Ca 2+ channel blocker. IC 50 values are 6.8 and >100 μM for Ca v 3.1 T-type channels and HVA currents, respectively. Crosses the blood-brain barrier.
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

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Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid504769145
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504769145
IUPAC Name [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] cyclopropanecarboxylate;dihydrochloride
INCHI InChI=1S/C30H38FN3O2.2ClH/c1-20(2)28-24-13-12-23(31)19-22(24)14-15-30(28,36-29(35)21-10-11-21)16-18-34(3)17-6-9-27-32-25-7-4-5-8-26(25)33-27;;/h4-5,7-8,12-13,19-21,28H,6,9-11,14-18H2,1-3H3,(H,32,33);2*1H/t28-,30-;;/m0../s1
InChi Key BCCQNBXHUMKLFW-HNQRYHMESA-N
Canonical SMILES CC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)C5CC5)C=C(C=C2)F.Cl.Cl
Isomeric SMILES CC(C)[C@H]1C2=C(CC[C@@]1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)C5CC5)C=C(C=C2)F.Cl.Cl
PubChem CID 22084904
Molecular Weight 564.6

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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5 results found

Lot NumberCertificate TypeDateItem
B2307754Certificate of AnalysisNov 14, 2023 N274718
B2307755Certificate of AnalysisNov 14, 2023 N274718
B2307757Certificate of AnalysisNov 14, 2023 N274718
B2307770Certificate of AnalysisNov 14, 2023 N274718
B2307774Certificate of AnalysisNov 14, 2023 N274718

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